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LAKESIDE, Calif. (KGTV) -- Officials with the Lakeside Union School District confirmed the closure of Winter Gardens Elementary School due to a COVID-19 outbreak.In a letter sent to families and school personnel Thursday, LUSD Superintendent Dr. Andy Johnsen acknowledged that “there have been 12 positive cases identified at Winter Gardens over the last two weeks” and because of the outbreak, the campus on 8501 Pueblo Rd. would be closed for 15 days starting Dec. 4.The school’s Extended School Services (ESS) will also be shut down.Dr. Johnsen said they closed the school Friday as, "all of the other cases we've had up until this point no other person has been identified as a close contact."Winter Gardens Elementary will proceed with distance learning from Dec. 4-18, according to Dr. Johnsen. The initial plan is to reopen the campus for in-person learning on Jan. 4.Dr. Johnsen noted that “staff members and students that may have come into close contact with the positive individuals have been directly contacted by San Diego County Public Health with further instructions.”“Because of how COVID-19 spreads, public health officials have indicated that all of us should consider ourselves as being potentially exposed,” Dr. Johnsen said in the letter.Dr. Johnsen said the infections likely originated off-campus. A La Jolla Immunologist agreed with that theory, saying on the molecular level adults are more likely to pass the virus to each other and not get it from children.Dr. Johnsen said the 12 infections is out of 308 students and staff combined. He said public health officials recommend closing schools when they reach a 5% infection threshold.He said students and staff were wearing masks, socially distant and the district hired cleaning staff to sanitize high touch points each hour and classrooms overnight. When the school reopens, Dr. Johnsen said they will not make any changes to their protocol, adding the district and public health officials support the procedures they have in place.Johnsen would not identify how many students and staff each were infected, due to privacy laws. 2115

LEMON GROVE, Calif. (KGTV) - An explosive fire broke out Wednesday afternoon at a home in Lemon Grove, Heartland Fire officials said.The flames erupted at 1783 Dupont Drive just before 4 p.m. and were accompanied by explosions, according to firefighters. When crews arrived at the scene, the home was 50 percent engulfed in flames.The Sheriff's Department told 10News neighboring homes were evacuated due to the safety risk.Crews at the scene resuscitated a cat in the front yard, 10News reporter Matt Boone said. It ran away after crews helped it.No one was injured.There was no immediate word on the cause of the fire. 628

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched."  6969

LA JOLLA, Calif. (KGTV)— Scientists all over the world are now studying last night’s 7.1M earthquake near Ridgecrest, CA. Seismologists say we should be expecting another big quake in the near future. It seemed like deja vu — a 6.4M followed by a 7.1M, just one day later. “Some people would like to call them separate events, but I don’t think they are separate events,” UCSD Seismologist Dr. Debi Kilb said. Kilb believes neither jolt was a foreshock or an aftershock. She considers these two quakes “mainshocks,” in what is called a “doublet sequence.”“Because the space and time of these earthquakes are so close together, we are beginning to call them an earthquake doublet. So that includes the pair of 6.4 earthquake and the 7.1 earthquake,” Dr. Kilb said. Not only did it shake for several seconds, tremors were also felt from across the state, and even in Arizona. Like the first big earthquake on July 4, the 7.1M was another rare one. The quake was not along a known fault line. Instead, scientists say this may map out a brand new fault.“It was a right lateral fault, meaning that the [earth’s] material on this [east] side moved to the right and down and the material on this [west] side moved up,” Dr. Kilb said. Luckily, California’s most massive quake in 20 years occurred in a rural area, meaning injuries and damages were minimal. But Dr. Kilb says living in California, we are never completely out of the woods. “We live in earthquake country,” Dr. Kilb said. “And earthquakes happen all the time, and they will often be a surprise. Right now the reporting is that there is a one in 20 chance that we will have another 7.0M or greater.” 1664

LAUSANNE, Switzerland — Breakdancing has been confirmed as an official Olympic sport. The International Olympic Committee’s pursuit of urban events to lure a younger audience saw street dance battles officially added to the medal events program at the 2024 Paris Games. The IOC executive board also confirmed skateboarding, sport climbing and surfing for Paris. Those three sports will make their Olympic debuts at the Tokyo Games which were postponed because of the coronavirus pandemic. Ahead of the announcement, International Olympic Committee president Thomas Bach praised the additions, describing them during an interview in 2019 as events that will make the Summer Games "more gender balanced, more youthful and more urban."Breaking, the preferred term by those who practice breakdancing, actual made its Olympic debut already. It was part of the 2018 Summer Youth Games in Buenos Aires. The Tokyo opening ceremony is July 23, 2021. Paris organizers need time to prepare and so the IOC kept its schedule to confirm the 2024 sports this month. 1058