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SYDNEY, July 1 (Xinhua) -- Breastfeeding mothers should limit their use of codeine-containing painkillers to four days as they can cause harm, an Australian doctor warned on Friday.The warning is being discussed at a meeting of anesthetists in Sydney."New mothers should limit their use of codeine-containing painkillers to no more than four days and, if they feel drowsy while taking this medication, cease its use and have their baby examined by a doctor for signs of drowsiness," Sydney's Royal North Shore Hospital anesthetist Dr. Gavin Pattullo said."This is because codeine needs to be metabolized by the liver into morphine to offer pain relief and this liver conversion process is very unpredictable," Pattullo said."Some patients' livers produce large amounts of morphine after taking codeine, causing drowsiness, while others fail to produce any morphine at all."Pattullo said for breastfeeding mothers, a large dose of morphine could make its way into the baby and result in the baby's death by overdose."While new mums shouldn't be unnecessarily alarmed, they need to be aware that codeine-containing painkillers in certain circumstances can cause harm," he said.Breastfeeding mothers are being advised to see a doctor if their baby gets sleepy while taking the painkillers.

LOS ANGELES, June 9 (Xinhua) -- The edge of our solar system may not be smooth, but filled with a turbulent sea of magnetic bubbles approximately 100 million miles (160 million kilometers) wide, NASA's Jet Propulsion Laboratory (JPL) said on Thursday.The finding was based on observations from NASA's Voyager spacecraft, humanity's farthest deep space sentinels, said JPL in Pasadena, Los Angeles.While using a new computer model to analyze Voyager data, scientists found the sun's distant magnetic field is made up of bubbles which are created when magnetic field lines reorganize, said JPL.The new model suggests the field lines are broken up into self- contained structures disconnected from the solar magnetic field, according to JPL."The sun's magnetic field extends all the way to the edge of the solar system," said astronomer Merav Opher of Boston University. "Because the sun spins, its magnetic field becomes twisted and wrinkled, a bit like a ballerina's skirt. Far, far away from the sun, where the Voyagers are, the folds of the skirt bunch up."Like Earth, our sun has a magnetic field with a north pole and a south pole. The field lines are stretched outward by the solar wind, a stream of charged particles emanating from the star that interacts with material expelled from others in our corner of the Milky Way galaxy.Understanding the structure of the sun's magnetic field will allow scientists to explain how galactic cosmic rays enter our solar system and help define how the star interacts with the rest of the galaxy.The Voyager spacecraft, more than nine billion miles (14 billion kilometers) away from Earth, are traveling in a boundary region. In that area, the solar wind and magnetic field are affected by material expelled from other stars in our corner of the Milky Way galaxy.Launched in 1977, the Voyager twin spacecraft have been on a 33- year journey. They are en route to reach the edge of interstellar space. JPL built the spacecraft and continues to operate them.

WELLINGTON, June 7 (Xinhua) -- Scientists in New Zealand have developed a new drug to fight previously untreatable hypoxic cancer tumors, which form in areas of the body starved of oxygen.The researchers at the Auckland University have entered an agreement for the clinical development of CEN-209, which was developed over 10 years of research, said a statement from the university Tuesday.CEN-209 was designed to enhance the effectiveness of radiotherapy and chemotherapy in solid hypoxic tumors, which were resistant to standard cancer therapies, said the statement. In lung cancer patients for example, about half of tumors had hypoxic regions.The new drug worked by damaging the DNA of hypoxic cancer cells, while leaving normal, healthy tissues alone.CEN-209 was designed and created by researchers at the university's Auckland Cancer Society Research Centre (ACSRC), using computer models of drug transport within tumors to accurately predict the anti-tumor activity of the drugs."Our computer models of drug transport developed in-house allowed the synthetic chemists to test their design theories and considerably shortened the discovery process," said Associate Professor Michael Hay, who led the ACSRC research chemists."CEN-209 improves markedly on previous agents in this class in terms of its ability to penetrate tumors, and this is reflected by its improved activity in the laboratory, when combined with long or short courses of radiotherapy," said researcher Professor Bill Wilson.Under the agreement between the university's Auckland UniServices Ltd. and California-based Centella Therapeutics, Inc., a subsidiary of Varian Medical Systems, Inc., Centella will have exclusive rights to CEN-209, which it will develop and trial with Cancer Research UK.The work on CEN-209 is the culmination of a program initiated with funding from the U.S. National Cancer Institute, and more recently from the Maurice Wilkins Centre for Biodiscovery. Ongoing preclinical research on CEN-209 and a backup compound was funded by grants from the Auckland Medical Research Foundation, Genesis Oncology Trust and Health Research Council of New Zealand, said the statement.

WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.

BRUSSELS, May 31 (Xinhua) -- A deadly outbreak of E.coli linked to contaminated cucumbers is sending Europe on high alert, as death toll from the disease climbed to 16 till Tuesday.So far, 15 people have reportedly died and more than 300 were seriously ill from infections linked to tainted vegetables in Germany. Experts said the numbers are expected to increase in the coming week."We hope the number of cases will go down but we fear it will worsen," said Oliver Grieve, spokesperson with the University Medical Center Schleswig where most German victims are being treated.The German government has identified the pathogen as hemolytic-uremic syndrome (HUS), a serious complication of a type of E. coli known as Shiga toxin-producing E.coli (STEC). The bacteria could damage blood cells and kidneys, and hence cause deaths.A woman in her 50s was confirmed to be the first fatal victim out of Germany by a local hospital on Tuesday. Officials at the hospital in Boras, southwestern Sweden, said the woman, who had recently traveled to Germany, was admitted on May 29.Swedish health authorities already said on Sunday that 36 people, all linked to travel in northern Germany, had been confirmed to have infected with E.coli, whereas cases were also reported in France, the Netherlands, Denmark and Britain.It was the second food scare for European consumers this year. In January, highly toxic dioxin was found in eggs, poultry and pork products across Germany.

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