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One person has been confirmed dead after a huge fire engulfed and destroyed an apartment building in the Brazilian city of Sao Paulo early Tuesday, according to state-run news agency Agencia Brasil.The dramatic fire broke out on the fifth floor of the 26-story building, which collapsed in a fireball an hour and a half later, according to the Brazilian Civil Defense.Seven other buildings were evacuated in the surrounding area. The blaze started at 1:36 a.m., according to a Sao Paulo Fire Department spokesman.The building was owned by the federal government and had previously served as the headquarters of the Federal Police. At the time of the fire it was occupied by low-income families who were part of the Front for Fighting for Housing, a social organization that advocates for fair housing, Agencia Brasil reported. 834

Ocasek was born in Baltimore. He and friend Benjamin Orr played in a number of bands before eventually officially forming the Cars in 1976. They released their self-titled debut album in 1978, which featured the hit singles “Good Times Roll,” “My Best Friend’s Girl,” and “Just What I Needed.” Following five more albums and hits like “Drive” and “Shake It Up,” the group broke up in the late 1980s.Starting with 1982’s Beatitude and ending with 2005’s Nexterday, Ocasek released a series of solo albums. He was also a producer of albums by artists including Weezer, Bad Brains, Suicide, Guided By Voices, No Doubt, the Cribs, Bad Religion, and others.The musician and producer was also a pop culture fixture beyond music. He made a memorable appearance in John Waters’ Hairspray as a painter. He was an artist in real life, too, and his work was shown in galleries. He also wrote books, including the 1992 poetry collection Negative Theater. He was a regular guest on “The Colbert Report,” once calling out Todd Rundgren on the show (at a time when Rundgren was fronting the Cars under the name “the New Cars”). He appeared on the 1140

One COVID-19 vaccine in development may be ready for review in December.Executives at Novavax say they are enrolling volunteers for a second phase of clinical trials now. The data should be ready for review within a few months.Phase 1 data showed the two-dose vaccine in healthy adults produced antibodies in all participants. Tenderness and pain were the most frequent local symptoms.When the first COVID-19 vaccines are approved, we won't know a whole lot about their safety.“We’re going to learn as we go along. There are numerous case studies in our experience where, as vaccines were rolled out, we were quite confident with the safety profile, but that evolves,” said Dr. Jon Andrus, adjunct professor at George Washington University’s Milken Institute School of Public Health.“I think that these vaccines will be safe in the sense that they won’t cause a serious or permanent adverse event when tested in 10,000, 15,000, 20,000people,” said Dr. Paul A. Offit with the Children’s Hospital of Philadelphia. “Hopefully, that will also be true in post approval when it’s tested and seen in 20 million, 30 million people.”Based on other vaccine history, a COVID-19 vaccine will likely produce some sort of adverse reaction. It could be minor typical injection site issues or something more serious.Back in the 1950s, the very first massive polio vaccination program was stopped because it paralyzed some children and killed a handful.In the 70s, the swine flu vaccine caused a very small amount of rare neurological cases. There are other issues like an allergic reaction or seizure.Still though, experts say vaccines are one of the greatest advances in modern medicine in preventing unnecessary deaths.“There is no better cost-effective intervention that medical science has to offer with the exception of safe water and sanitation, so when you look at our life expectancy, vaccines have been incredibly important,” said Andrus.The Vaccine Injury Litigation Clinic handles cases of vaccine-related injuries and deaths. They have on average just over 600 people per year receive payouts from the National Vaccine Injury Compensation Program. But they admit vaccine injuries are still rare compared to the overall numbers of administered vaccines every year.The Centers for Disease Control and Prevention (CDC) says for every 1 million doses of vaccines that were distributed, one person was compensated. 2413

OCEANSIDE, Calif. (KGTV) -- A woman was arrested in Oceanside after trying to smuggle methamphetamine with her 7-year-old in the car. Border Patrol agents pulled the woman over near the Oceanside Harbor Interstate 5 exit just after 4 p.m. Tuesday. After becoming suspicious of the driver’s behavior, agents found more than 48 pounds of the drug inside a duffle bag in the trunk. RELATED: Woman tries to smuggle drugs into the U.S. with five kids in van, CBP saysThe drugs, according to Border Patrol, have an estimated street value of more than ,000. The 26-year-old driver, a Mexican national with a valid tourist visa, was arrested for felony drug trafficking. The minor child was placed in the care of local child protective services. RELATED: Border Patrol finds drugs hidden in child's car seatSince Oct. 1, 2019, the agency says it has seized more than 750 pounds of methamphetamine worth more than ,427,000. 928

Oklahoma teachers will continue their walkout for a sixth day Monday, maintaining their pressure on state legislators for increased education funding.The teachers were granted a pay raise last month but say the state's school facilities, equipment and textbooks are rundown, outdated or in short supply and more spending is needed.At least 58 of the state's 500-plus school districts -- including those in Oklahoma City and Tulsa -- will be closed Monday because of the walkout, CNN affiliate KOCO reported. 515

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