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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.

SAN FRANCISCO, Dec. 15 (Xinhua) -- Microsoft on Thursday announced that it will automatically upgrade the Internet Explorer (IE) to the latest version to give Windows customers more protection against malicious software.According to the company's blog post, starting from Australia and Brazil next January, users of Windows XP, Vista and Windows 7 will get the IE updates if they have turned on automatic updating via Windows Update.Microsoft said the industry has been moving toward automatic updates as a norm since the biggest online threat these days is social engineering malware typically targeting outdated software like Web browsers.Automatic upgrades, also called silent updates for displaying no messages or windows during the progress, has been deployed by Google's Chrome and Mozilla's Firefox. It can ensure users have the newest versions of the browser, and therefore is seen as a big improvement to Internet security.According to the Microsoft Security Intelligence Report released in October, 99 percent of all attacks during the first half of 2011 came from unpatched but known vulnerabilities, and 90 percent of infections were attributed to vulnerability exploitation that had a security update available from the software vendor for more than a year.In the latest research data from Web analytics company StatCounter, Microsoft's IE has a strong lead with 40.63 percent of global browser market share, followed by 25.7 percent of Chrome and 25.23 percent of Firefox.

PARIS, Oct. 15 (Xinhua) -- Faced with new problems such as sovereign debt and downward risks, all countries should work together to enhance coordination on macroeconomic policies to guard economic growth and financial stability with respective effort, Chinese delegates said Saturday here at the G20 Financial Ministers Meeting.The global economy is challenged by new difficulties which require all countries to join hands in fighting all sorts of protectionism either in trade or in investment, according to a statement issued by the Chinese delegation led by Chinese Financial Minister Xie Xuren and Central Bank Governor Zhou Xiaochuan.China suggested that leading developed countries should ensure economic recovery and financial stability in short term, while in the medium term enhance fiscal solidarity, accelerate structural reform and refrain the negative impact of macroeconomic policies.Meanwhile, China also stressed that the emerging countries should make their own contribution to tackle the problems. "The emerging markets should promptly take flexible and effective macroeconomic measures in order to control slowdown and tackle with impacts from inflation and capital flows," the statement said.Emerging economies "should also quicken their pace on structural reform in a bid to realize stable and faster growth," the statement added.During the two-day meeting, G20 financial leaders gathering in Paris welcomed the progress the Europe made on the eurozone debt issue on Saturday, but meanwhile expected the euro area to rely more on itself with bigger bailout fund to avoid contagion.

BEIJING, Nov. 19 (Xinhua) -- China on Saturday again called for appropriately addressing the alleged plot to assassinate the Saudi Arabian Ambassador to the United States.Foreign Ministry Spokesman Liu Weimin made the remarks in a written statement in Beijing.The UN General Assembly on Friday adopted a resolution titled "Terrorist Attacks on Internationally Protected Persons," expressing deep concern over the assassination plot and calling on Iran "to comply with all of its obligations under international law."Liu said China abstained from the vote on the resolution, because the case is highly complicated and sensitive at present and relevant parties still have different views on the issue.He said any conclusion or action must be based on comprehensive, impartial, objective and transparent investigation and substantial evidence."Before facts are checked out, parties should adopt a prudent attitude, refrain from jumping to conclusions, and avoid actions that may complicate and worsen the situation," he said.He said China hopes those countries concerned will continue to appropriately address the issue through dialogue and make joint efforts to maintain peace and stability in the Middle East and the Gulf Region.Liu also reaffirmed that China opposes all forms of terrorism, and always stands for compliance with international law and the basic norms governing international relations in handling state-to-state relations as well as the effective protection of the safety of diplomatic personnel.Chinese Permanent Representative to the United Nations Li Baodong previously addressed the UN General Assembly on Friday in order to explain China's position on the issue after he abstained from voting on the draft resolution.

来源：资阳报