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TORONTO (AP) — The NHL believes all seven Canadian teams will be able to start the season playing in their home arenas.NHL Deputy Commissioner Bill Daly said Thursday the league believes it is clear to play in Canada during the second wave of the COVID-19 pandemic after discussions with the five provincial governments with NHL teams to try to gain approval to start Jan. 13.The NHL realigned its divisions for the season so that the North Division — which features all seven Canadian teams — would not have to cross the U.S.-Canada border, which remains closed to non-essential travel until at least Jan. 21.The league released its schedule Wednesday, with each team playing 56 games instead of the usual 82.On Tuesday, the league released its coronavirus-related protocols, which include coaches must wear masks at all times while behind the bench, owners can't have face-to-face meetings with players, and teams can only travel with up to 50 people, according to the Associated Press.The AP also reported that the league had asked the players not to go to restaurants, bars, and clubs and not have outside guests at their homes. 1140

Thomas Lane, one of the four former Minneapolis officers arrested in connection with the death of George Floyd, posted bail on Wednesday according to jail records.Lane was among the three officers who were charged with aiding and abetting a murder. The fourth officer, Derek Chauvin, was charged with murder.Lane's bail was set at 0,000 following his arrest last week.Lane was on his fourth day with the Minneapolis Police when Floyd died in his custody. The four officers were fired one day after Floyd’s death.Floyd died after Chauvin held a knee to Floyd’s neck for nearly nine minutes. 600

The Boston Red Sox made sure to savor their Game 4 win over the New York Yankees in the American League Division Series on Tuesday.The Red Sox played Frank Sinatra's edition of "New York, New York," a staple at Yankee Stadium, as they celebrated advancing to the American League Championship Series.Boston was merely returning the favor after Yankees star Aaron Judge had the song echoing throughout the inside of Fenway Park following New York's Game 2 victory on Saturday.The Yankees nearly erased what had been a 4-0 deficit Tuesday. They scored two runs in the ninth inning off Red Sox closer Craig Kimbrel and had the tying and go-ahead runs on base when Gleyber Torres grounded out to end the game.The Red Sox are headed to the ALCS for the first time since their World Series victory in 2013.  833

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

Today has been a trying day for our family. We’re thankful to everyone who has reached out with their concerns. Our daughter is in good care at Arnold Palmer Hospital and is doing well. My wife was also treated for her injury and has been released from the hospital. At this time, we ask for privacy as we focus on our daughter’s recovery. 347