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When you leave the big cities and head out to lesser populated areas of the United States, you realize President-elect Joe Biden may have won but President Donald Trump still enjoys plenty of support. "Since I was 18, I voted for Democrats, every time, but this year I voted for Trump," Scott Will, a new Trump voter in Westmoreland County, Pennsylvania, said. "My dad, he is a Joe Biden fan. He is calling me and teasing me about," Will said jokingly. While Trump is projected to lose the 2020 election, he did set voting records. Thus far, Trump has received more than 10 million more votes than four years ago. That is more votes than any American presidential candidate in history, except Biden. CHANGING REGIONS POLITICALLY While he lost the election, Trump did improve his margins in several key areas around the country. In Kenosha County, Wisconsin, Trump did 3% better. In Miami-Dade County, Florida, Trump did `12% better. And in Mahoning County, Ohio Trump actually flipped this county for the first time since Eisenhower. For perspective, this county, which includes Youngstown, Ohio, went for the Obama/Biden ticket in 2008 by 30 points. "The funny thing here is Trump stole the Democratic message. Can the Democrats steal it back?" Paul Sracic, a political scientist at Youngstown State University, said. Sracic said in defeat, Trump's legacy maybe forever changing politically places like Youngstown. Sracic said old trade deals, like NAFTA, were particularly toxic in this part of Ohio and voters rewarded Trump for getting rid of it and promising old jobs would come back. "Trump didn’t create these voters, they were waiting for Trump," Sracic said.WILL THESE VOTERS RESPECT BIDEN? At Thanos Restaurant in Mahoning County, Ohio, diners here know how Trump changed this area's politics. Ken Morrow eats here twice a day. In 2016, he voted for Bernie Sanders. In 2020 he voted for Trump. "For me, it's confusing," Morrow said, commenting on the election results and Trump's refusal to concede. His advice to Biden? "We need a lot of good paying jobs around here, everything is gone," Morrow said. Every Trump voter we spoke with said they would respect Biden come January 20th."I am very conservative," Jean Hasey said. "He’s going to be my president because I'm an American and a patriot," Hasey added. But she said -- uniting the country may be a tall task. "I think it’s going to be hard, very very hard," Hasey added. 2447

While families prepare to sit down together this Thanksgiving, there are many people across the country who aren't as fortunate. Charities and homeless shelters that normally prepare a warm Thanksgiving meal for those in need are having to make some changes this year due to the pandemic."The importance of Thanksgiving is not these big celebrations with the bells and whistles -- of course it is incredible to be able to be there with one another -- but it's really about providing that meal for those who are experiencing homelessness. And so, we really focused on how to still be able to provide that meal during Thanksgiving to those people," says Nicole Tschetter with the Denver Rescue Mission.The Denver Rescue Mission usually has a large banquet and celebration with the Colorado Governor and other prominent members of the community coming out to bring attention to homelessness, and serve hot meals to those in need. This year, the organization is scaling down, serving meals at two smaller locations."The people that are eating there are the people that are staying at those specific locations," says Tschetter.Tschetter still expects the Denver Rescue Mission will serve several thousand meals this Thanksgiving, just in a safe, physically distant manner.Union Station Homeless Services in Los Angeles County is serving many of their Thanksgiving meals "to go.""It's both a to-go meal for the pre-prepared ones or a fix-it-yourself, kind of like a grocery box full of lunch. So, whichever is the easiest for people. We want people to be able to share meals with their friends or family in their safe bubble and this provides two opportunities for people to get food," says Union Station Homeless Services CEO Anne Miskey.Miskey says they have fewer volunteers than normal this year, but the need they're seeing is great. A need not just for food or shelter but also human kindness."How do we recognize other people’s humanity? How do we have touch points even if we can’t physically touch people or get closer than 6 feet? How do we continue to show people we care, we’re here, we continue to help and support you," says Miskey.Tschetter recalls the story of a prior guest of the Denver Rescue Mission."It makes the world of a difference to be able to sit down and have food and, you know, I don’t remember the last time I had a warm meal and to just feel loved and feel a sense of dignity and a sense of normalcy is just such a huge thing for people who are experiencing homelessness," says Tschetter.These organizations are recognizing the importance of giving back and appreciating all we have to be thankful for in the midst of a pandemic. 2663

With a coronavirus vaccine still months off, companies are rushing to test what may be the next best thing: drugs that deliver antibodies to fight the virus right away, without having to train the immune system to make them.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. Vaccines work by tricking the body into thinking there’s an infection so it makes antibodies and remembers how to do that if the real bug turns up.But it can take a month or two after vaccination or infection for the most effective antibodies to form. The experimental drugs shortcut that process by giving concentrated versions of specific ones that worked best against the coronavirus in lab and animal tests.“A vaccine takes time to work, to force the development of antibodies. But when you give an antibody, you get immediate protection,” said University of North Carolina virologist Dr. Myron Cohen. “If we can generate them in large concentrations, in big vats in an antibody factory ... we can kind of bypass the immune system.”These drugs are believed to last for a month or more and could give quick, temporary immunity to people at high risk of infection, such as health workers and housemates of someone with COVID-19. If they proved effective and if a vaccine doesn’t materialize or protect as hoped, the drugs might eventually be considered for wider use, perhaps for teachers or other groups.They’re also being tested as treatments, to help the immune system and prevent severe symptoms or death.“The hope there is to target people who are in the first week of their illness and that we can treat them with the antibody and prevent them from getting sick,” said Dr. Marshall Lyon, an infectious disease specialist helping to test one such drug at Emory University in Atlanta.Having such a tool “would be a really momentous thing in our fight against COVID,” Cohen said.Vaccines are seen as a key to controlling the virus, which has been confirmed to have infected more than 20 million people worldwide and killed more than 738,000. Several companies are racing to develop vaccines, but the results of the large final tests needed to evaluate them are months away.The antibody drugs are “very promising” and, in contrast, could be available “fairly soon,” said Dr. Janet Woodcock, a U.S. Food and Drug Administration official who is leading government efforts to speed COVID-19 therapies. Key studies are underway and some answers should come by early fall.One company, Eli Lilly, has already started manufacturing its antibody drug, betting that studies now underway will give positive results.“Our goal is to get something out as soon as possible” and to have hundreds of thousands of doses ready by fall, said Lilly’s chief scientific officer, Dr. Daniel Skovronsky.Another company that developed an antibody drug cocktail against Ebola — Regeneron Pharmaceuticals Inc. — now is testing one for coronavirus.“The success with our Ebola program gives us some confidence that we can potentially do this again,” said Christos Kyratsous, a Regeneron microbiologist who helped lead that work.Regeneron’s drug uses two antibodies to enhance chances the drug will work even if the virus evolves to evade action by one.Lilly is testing two different, single-antibody drugs — one with the Canadian company AbCellera and another with a Chinese company, Junshi Biosciences. In July, Junshi said no safety concerns emerged in 40 healthy people who tried it and that larger studies were getting underway.Others working on antibody drugs include Amgen and Adaptive Biotechnologies. The Singapore biotech company Tychan Pte Ltd. also is testing an antibody drug and has similar products in development for Zika virus and yellow fever.“I’m cautiously optimistic” about the drugs, said the nation’s top infectious diseases expert, Dr. Anthony Fauci. “I’m heartened by the experience that we had with Ebola,” where the drugs proved effective.What could go wrong?— The antibodies may not reach all of the places in the body where they need to act, such as deep in the lungs. All the antibody drugs are given through an IV and must make their way through the bloodstream to wherever they’re needed.— The virus might mutate to avoid the antibody — the reason Regeneron is testing a two-antibody combo that binds to the virus in different places to help prevent its escape.Skovronsky said Lilly stuck with one antibody because manufacturing capacity would essentially be cut in half to make two, and “you will have less doses available.” If a single antibody works, “we can treat twice as many people,” he said.— The antibodies might not last long enough. If they fade within a month, it’s still OK for treatment since COVID-19 illness usually resolves in that time. But for prevention, it may not be practical to give infusions more often than every month or two.A San Francisco company, Vir Biotechnology Inc., says it has engineered antibodies to last longer than they usually do to avoid this problem. GlaxoSmithKline has invested 0 million in Vir to test them.Giving a higher dose also may help. If half of antibodies disappear after a month, “if you give twice as much, you will have two months’ protection,” Lilly’s Skovronsky said.— The big fear: Antibodies may do the opposite of what’s hoped and actually enhance the virus’s ability to get into cells or stimulate the immune system in a way that makes people sicker. It’s a theoretical concern that hasn’t been seen in testing so far, but large, definitive experiments are needed to prove safety.“As best as we can tell, the antibodies are helpful,” Lyon said.___Marilynn Marchione can be followed on Twitter: @MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 5919

When it comes to educating America's children, how much of a difference could million make? Could it send a second grader on a school trip to the museum, or provide updated equipment to a class of budding scientists?It can. In fact, it can do it 35,647 times.Ripple, a cryptocurrency and international payment company, has donated million in cryptocurrency to DonorsChoose.org, a donation platform that connects people to classroom needs across the country. With the money, Donors Choose was able to fulfill every single classroom project request on its site -- 35,647 requests in all, from 28,210 teachers at 16,561 public schools."It's fair to say there's never been a day that this many classroom dreams have come true," Donors Choose founder Charles Best told CNN.The Colbert bumpThe massive donation is the culmination, or grand finale, if you will, of the site's #BestSchoolDay project. Two years ago, Stephen Colbert, who is a member of the Donors Choose board of directors, announced he was going to pay for every school project request in his home state of South Carolina.His act of kindness set off a movement that became known as #BestSchoolDay."More than 50 actors, athletes and philanthropists were inspired to fund classrooms in their states," Best told CNN. "Together, those 50-plus people gave more than million, and to use, that represented the idea of a best school day."Best says the response has been overwhelming -- in a good way."An outpouring of joy would not be an overstatement," he said.The Ripple effectBest says when the organization connected with Ripple, the cryptocurrency management company was "inspired to think of the impact" of such a significant gift."At Ripple, we care about giving back to our community and we collectively value the importance of quality education in developing the next generation of leaders," Ripple's SVP of Marketing Monica Long said in a statement."DonorsChoose.org's track record speaks for itself — they are highly effective at improving the quality of education and the experience of teachers and students across America. We're proud to work with them to support classroom needs across the country."According to Ripple's company site, the donation will affect approximately 1 million public school students.Best says the "classroom projects" requested on the site represent specific missions or activities that teachers have for their students."It's a public schoolteacher requesting a classroom library. A field trip. A set of art supplies. A pair of microscopes. It's about requesting experiences or tools to provide a student learning experience," he said."We believe in the wisdom of the front lines," Best added. "Hardworking, passionate teachers know their students' needs better than anyone else in the school environment. If we can tap into their needs, we can unleash smarter solutions and empower those people on the front lines."  2956

With Georgia playing a key role in this year’s presidential election, Democrats in the state are reminding voters to check the status of their ballot before a 5 p.m. Friday deadline.Voters in Georgia have until then to “cure” their ballot as the state has a rule that allows people who have their ballot rejected for administrative reasons, such as forgetting a signature, to fix their ballot. Ballots not cured by 5 p.m. Friday are thrown out.Georgia is not the only state that allows for ballot curing. According to the National Association of State Legislatures, 18 states have rules that allow voters to correct errors such as signature discrepancies. While in some states, the deadline to fix such discrepancies has passed, in other states, voters have up to three weeks to fix their ballot depending on the state.Other close states that allow ballot curing include Nevada and Arizona. Nevada gives voters seven days to correct a signature discrepancy. Arizona gives voters five days to make a correction.Pennsylvania is a state that does not have a process for ballot curing. According to WPVI-TV, some counties allowed voters to cure their ballot, prompting a lawsuit from Republicans. According to WPVI, nearly 1,600 voters in Bucks County had their ballot rejected, many for not properly placing their ballot inside of the “secrecy envelope," as voters in Pennsylvania are required to place their ballot inside an unmarked envelope, which is placed inside a marked envelope.In most states that permit ballot curing, elections officials are to notify voters of the discrepancy immediately. But with thousands of ballots being counted, there are questions on whether election officials are able to reach all voters.Stacey Abrams, a prominent Georgia Democrat who had an unsuccessful bid for governor in 2018, launched a website “CheckMyBallot.net” which allows voters in key battleground states to check the status of their mail-in or provisional ballot.What voters aren’t able to do through vote curing is change their vote. 2040