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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

Detroit has one of the highest violent crime rates in America, according to the FBI.The challenges here have opened the door for a growing industry: private security. “The landscape is growing, because there is a greater need for protection than ever before,” says Dale Brown. “Our mission is to protect that person’s business from a violent encounter."Brown is the founder of the 394

NASHVILLE, Tenn. – In Nashville, Tennessee, music is everywhere and everything. Whether at a Honky Tonk on world-famous Broadway or at a dive bar on Demonbreun, musicians are playing with a passion and singing their hearts out. But after a natural disaster recently rocked Music City, USA, some musicians there are having a tough time getting back to making music “What they’ve used to earn a living and chase a dream is gone now,” said 452

Three Metro-North Railroad workers have been suspended for turning a storage room under Manhattan's Grand Central Terminal into an unauthorized “man cave” with a television, a refrigerator, a microwave, a futon couch and more.A Metropolitan Transportation Authority Inspector General investigation found that Metro-North managers were unaware of the hideaway in a storage room located behind a locked door, beneath Track 114.Railroad officials said Thursday that a wireman, a carpenter foreman and an electrical foreman have been suspended without pay pending disciplinary hearings.Inside the room, investigators found personal property and evidence that implicated the three employees. This included a receipt with the wireman's name on it, a streaming device connected to a hotspot associated with the carpenter foreman's phone, personal calendars, and a pull-up bar with a shipping sticker reading the name of the electrical foreman.The Office of the MTA Inspector General launched the investigation after learning of complaints about the room from anonymous tips, the MTA said.Metro-North President Catherine Rinaldi released the following statement Thursday: The behavior described in the IG’s report is outrageously inappropriate and is not consistent with Metro-North’s values and the commitment that we have to providing safe, reliable and cost-efficient service to our customers. All three employees were immediately suspended without pay and are being disciplined in accordance with their collective bargaining agreements. Officials said the hidden space presented a fire hazard because rescue workers would have had difficulty accessing an unmapped room. Mark Sundstrom contributed to this report, originally appearing on PIX11.com. 1777

If actor Scott Baio gets his way, Utah's first lady may soon be Joanie Cunningham and senatorial staff meetings will be held in the bathroom at Al's.A day after Sen. Mitt Romney criticized President Donald Trump's moves to hold up election results, Baio tweeted Friday that he might move to Utah and challenge for his seat.Baio, a staunch supporter of Trump and the Republican Party, mentioned the state's beautiful golf courses and said that after he plays "a few rounds," he'll unseat Romney. The actor known for his role in the sitcoms "Happy Days" and "Charles in Charge" went on to accuse Ann Romney of canceling a luncheon in Beverly Hills and keeping the campaign money for her husband. According to the star of "Bugsy Malone," his own wife is still waiting for her ,600 refund for the luncheon.Baio took umbrage to Romney's tweet Thursday that said "It is difficult to imagine a worse, more undemocratic action by a sitting American President" following Trump's efforts to undermine the presidential election that has been awarded to Joe Biden.If Baio chooses to follow through and challenge Romney, he'll have to wait a few years. Romney won't be up for re-election until 2024. Hey @MittRomney, beautiful golf courses in Utah......maybe I'll move there, play a few rounds and unseat you. P.S. My wife is still waiting for her 00 refund. Remember your wife canceled that Beverly Hills political luncheon fundraiser? But your campaign kept the money. https://t.co/ZMBZVZw3zZ— Scott Baio (@ScottBaio) November 20, 2020 This article was written by KSTU. 1595

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