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OCEANSIDE (CNS) - A pedestrian was hit and killed while crossing an Oceanside highway late Saturday night, police said.The crash was reported to police shortly before 10 p.m. Saturday at the intersection of state Route 76 and Douglas Drive, according to Oceanside police Sgt. Rick Davis.Officers found a man lying unresponsive in eastbound lanes of Route 76.Davis said according to witness statements and evidence at the crash scene, investigators believe the pedestrian was crossing Route 76 from north to south against a red light, and was hit by a car heading east on the highway with a green light.The driver, who was not injured, immediately stopped and waited for police to arrive, Davis said. Police did not suspect alcohol or drugs were factors in the crash.The name of the victim was not immediately released. 826

Once a COVID-19 vaccine is approved by the Food and Drug Administration, it will face another hurdle before being distributed in California.Governor Gavin Newsom announced Monday he has created a scientific safety review workgroup who will “independently review the safety and efficacy of any vaccine that received FDA approval for distribution,” according to his office.The workgroup is part of California’s COVID-19 vaccine distribution plan, which was submitted to the CDC on Friday. Every state was asked to submit an initial distribution plan to the Centers for Disease Control and Prevention in anticipation of when a vaccine will be widely available. 665

ONTARIO, Calif. – Even a coronavirus diagnosis couldn’t stop one California couple from saying “I do.”Lauren Delgado told NBC News that she tested positive for COVID-19 just five days before her wedding day and her marriage certificate was going to expire soon.So, Lauren and her fiancé, Patrick, replanned their nuptials and held their ceremony outside her mother’s home in Ontario, where the bride was quarantining.Like out of a Disney princess movie, Lauren sat at a second story window as she married the love of her life who stood below with the couple's masked loved ones.The couple’s wedding photographer, Jessica Jackson, captured the unusual yet beautiful moment when Lauren and Patrick exchanged vows. During the Nov. 20 ceremony, the bride and groom held a decorated ribbon in place of each other’s hands.“Yesterday was an actual COVID wedding and we had an actual COVID bride, but through the very extreme and rough circumstances, Lauren and Patrick still exchanged vows, rings, and an undying love for one another!” Jackson wrote on Facebook with the couple’s wedding photos.The couple wasn't able to physically spend their wedding night together, but Lauren told NBC that they ended the night by virtually watching a Netflix movie together and eating a Postmates dinner.The couple says they hope to celebrate their marriage with a larger ceremony once a COVID-19 vaccine is introduced and it’s safe to do hold big gatherings. 1447

On Tuesday, the U.S. State Department downgraded its travel warning for Mexico.The current land-border closure agreement between the U.S. and Mexico is due to expire on Sept. 21.The U.S.'s southern neighbor is no longer under a Level 4 "Do Not Travel" warning, the state department said.It's now been downgraded to Level 3 "Reconsider Travel" status.The agency says travelers still cannot go to:- Colima state due to crime - Guerrero state due to crime. - Michoacán state due to crime.- Sinaloa state due to crime.- Tamaulipas state due to crime and kidnapping.According to USA Today, travelers can fly to Cancun, Cozumel, and Cabo San Lucas, even without a negative COVID-19 test or quarantine. 703

One COVID-19 vaccine in development may be ready for review in December.Executives at Novavax say they are enrolling volunteers for a second phase of clinical trials now. The data should be ready for review within a few months.Phase 1 data showed the two-dose vaccine in healthy adults produced antibodies in all participants. Tenderness and pain were the most frequent local symptoms.When the first COVID-19 vaccines are approved, we won't know a whole lot about their safety.“We’re going to learn as we go along. There are numerous case studies in our experience where, as vaccines were rolled out, we were quite confident with the safety profile, but that evolves,” said Dr. Jon Andrus, adjunct professor at George Washington University’s Milken Institute School of Public Health.“I think that these vaccines will be safe in the sense that they won’t cause a serious or permanent adverse event when tested in 10,000, 15,000, 20,000people,” said Dr. Paul A. Offit with the Children’s Hospital of Philadelphia. “Hopefully, that will also be true in post approval when it’s tested and seen in 20 million, 30 million people.”Based on other vaccine history, a COVID-19 vaccine will likely produce some sort of adverse reaction. It could be minor typical injection site issues or something more serious.Back in the 1950s, the very first massive polio vaccination program was stopped because it paralyzed some children and killed a handful.In the 70s, the swine flu vaccine caused a very small amount of rare neurological cases. There are other issues like an allergic reaction or seizure.Still though, experts say vaccines are one of the greatest advances in modern medicine in preventing unnecessary deaths.“There is no better cost-effective intervention that medical science has to offer with the exception of safe water and sanitation, so when you look at our life expectancy, vaccines have been incredibly important,” said Andrus.The Vaccine Injury Litigation Clinic handles cases of vaccine-related injuries and deaths. They have on average just over 600 people per year receive payouts from the National Vaccine Injury Compensation Program. But they admit vaccine injuries are still rare compared to the overall numbers of administered vaccines every year.The Centers for Disease Control and Prevention (CDC) says for every 1 million doses of vaccines that were distributed, one person was compensated. 2413