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As questions arise over when a coronavirus vaccine should be granted FDA approval, the leaders of several major pharmaceutical companies announced they have signed a pledge not to rush the development of a vaccine.The companies, AstraZeneca, BioNTech, GlaxoSmithKline, Johnson, Merck, Moderna, Novavax, Pfizer and Sanofi, released a joint statement on Tuesday confirming the pledge.The pledge includes the following points:Always make the safety and well-being of vaccinated individuals our top priority.Continue to adhere to high scientific and ethical standards regarding the conduct of clinical trials and the rigor of manufacturing processes.Only submit for approval or emergency use authorization after demonstrating safety and efficacy through a Phase 3 clinical study that is designed and conducted to meet requirements of expert regulatory authorities such as FDA.Work to ensure a sufficient supply and range of vaccine options, including those suitable for global access.There has been pressure on both the FDA and manufactures to develop and approve a vaccine for the coronavirus. There have been more than 190,000 coronavirus-related deaths in the US since March, and the economic impact of the virus has cost millions of jobs.While most developed countries have not had the same public health pain as the US, the economic impact of the virus has been felt worldwide. The International Monetary Fund estimates a nearly 5% loss in global GDP in 2020.In Russia, the country claimed to begin distributing a coronavirus vaccine despite US-based vaccine candidates likely being months away from being able to demonstrate efficacy.The pressure domestically has also ratcheted up as President Donald Trump has suggested a vaccine could be ready by this fall’s presidential election."We're going to have a vaccine very soon... maybe even before a very special date, you know what date I'm talking about,” Trump said on Monday.In late August, the CDC told states to begin to prepare distributing a vaccine by Nov. 1. But Surgeon General Jerome Adams said that just because states will be ready to help distribute a vaccine on Nov. 1 does not mean a vaccine will be ready by then."We've always said that we're hopeful for a vaccine by the end of this year or the beginning of next year,” Adams told Good Morning America."We want to make sure states are available to distribute it," he added.The companies signing on the pledge said that the FDA has strict protocols for vaccine candidates. A typical vaccine trial takes one to three years, but the companies believe only a safe and effective vaccine will be granted approval.“FDA has established clear guidance for the development of COVID-19 vaccines and clear criteria for their potential authorization or approval in the US,” the companies wrote in the pledge. “FDA’s guidance and criteria are based on the scientific and medical principles necessary to clearly demonstrate the safety and efficacy of potential COVID-19 vaccines. More specifically, the agency requires that scientific evidence for regulatory approval must come from large, high quality clinical trials that are randomized and observer-blinded, with an expectation of appropriately designed studies with significant numbers of participants across diverse populations.” 3296

BALTIMORE — It's not just the news of a Free Little Library being vandalized that is turning heads in a Baltimore community. The narration of the crime itself is worth its weight in laughter."I thought it was hilarious when I sped it up and cut it," said Jacqui Cummings. "I said to myself, 'you don't need to fight over it, just make a joke of it.'"The initial vandalism happened on November 7th around 8 p.m. outside Notre Maison Connects. The non-profit focuses on empowering youth while supporting families and strengthening communities.Cummings is the founder of the organization. She said when she first saw the damage, she shed a tear."I did because I do a lot of work myself," she said.Cummings is no stranger to hands-on-work. Not only did she do metal-work to create the Free Little Library, she's experienced in hard labor, helping build day-care centers in other countries."I love giving back and educating," she said.In light of the vandalism Cummings launched a community book drive. So far more than 200 books have been donated."Some are children’s level books and some adult books," said Cummings " There are different books for all levels and I like that variety."This story originally reported by Dave Detling on WMAR2News.com. 1254

As users of Facebook log on to to the social media platform today, they may get a notice that apps they or their Facebook friends have used have been banned from it.It's a tool put in place to let users know Facebook is working to protect their data and provide awareness of previous potential data losses.Facebook's press page was once filled with announcements about new features to order food and connect to friends in virtual reality.Now it's almost entirely devoted to addressing Facebook's crisis of confidence. 525

As protests reached unprecedented levels on Wednesday, bolstered by professional athletes sitting out sporting events, Republicans offered a full-throated backing of police officers during Night 3 of the Republican National Convention.Featured on Wednesday, Michael McHale of the National Association of Police Organizations, went after the Biden campaign, who he claimed is “anti-police.”“I’m proud that the overwhelming majority of American police officers are the best of the best and put their lives on the line without hesitation. And good officers need to know their elected leaders and the department brass have their backs,” said McHale.Meanwhile, unrest unfolded in Kenosha, Wisconsin, following the shooting of Jacob Blake. Blake was shot seven times by Rusten Sheskey, a Kenosha Police officer who has since been placed on administrative leave.Investigators, speaking for the first time since Sunday's incident, declined to press charges on Wednesday against Sheskey despite the massive protests. Joining in the protests were athletes from the NBA, MLB and MLS, who took the unprecedented step to boycott playing as players demanded action against the officer who shot Blake. As the fourth night of demonstrations ensued in Kenosha, amid a summer of protests demanding changes to policing, Sen. Marsha Blackburn, R-Tenn., decried protests.“I'm talking about the heroes of our law enforcement and armed services. Leftists try to turn them into villains. They try to cancel them. But I'm here to tell you that these heroes can’t be canceled.,” Blackburn said.Mike Pence, accepting the GOP nomination for a second term as vice president Wednesday, tried to thread the needle between offering support for law enforcement while understanding the pain many Black Americans are experiencing. "We don’t have to choose between supporting law enforcement and standing with African American neighbors," Pence said.While Republicans multiple times claimed that Biden would defund policing, Biden has said he opposes defunding police departments. 2052

AUSTIN, Texas — A Texas man is making a statement by writing the names of 1,400 Black Americans who have died at the hands of police in the United States on his car.20-year-old Jeremiah Hindberg says he used a database to research Black Americans who have died at the hands of police in the U.S. and came up with 1,400 names.He wrote each one on his vehicle with a silver sharpie.Hindberg says he is using his car in hopes to start a conversation on what the Black Lives Matter movement means to him."A lot of sadness. I cried in my garage for hours," Hindberg said.It took several days to write the names, with George Floyd and Breonna Taylor on the hood."This is my representation of BLM," Hindberg said. "Some group of people that's being treated unfairly, and that should be fixed."Hindberg says the violence he and his father witnessed during the protests in Austin back in late May moved him more than anything he's ever experienced.The two served as medics and helped bring aid to injured protesters.He says many protesters were hurt by "less lethal" rounds fired by police, including his father who was shot in the arm and is still recovering from nerve damage today."It changed who my dad was fundamentally as a person," Hindberg saidAs a food delivery driver, Hindberg says reaction to the car ranges from being cursed out in grocery store parking lots to more warm moments of gratitude."She just looked at me in the eye, and said thank you so much she started to tear up and cry," Hindberg said, describing moments that remind him why he did this to his car. "Somebody knows that they're cared for. They're not just another number, they're not just another person."This story was originally published by KXXV in Waco, Texas. 1743

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