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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

The number of people worldwide who die from suicide is declining but one person still kills themselves every 40 seconds, according to new figures from the World Health Organization, which said countries needed to do more to stop these preventable deaths.Between 2010 and 2016, the global suicide rate decreased by 9.8%, the UN health body said in its second report on the issue. The only region to see an increase was the Americas."Every death is a tragedy for family, friends and colleagues. Yet suicides are preventable. We call on all countries to incorporate proven suicide prevention strategies into national health and education programs in a sustainable way," said WHO Director-General, Dr. Tedros Adhanom Ghebreyesus.WHO said close to 800,000 people die by suicide every year, more than those lost to malaria, breast cancer, or war and homicide, calling it a "serious global public health issue." It said only 38 countries had suicide prevention strategies.Suicide rates were higher than the global, age-standardized average -- 10.5 per 100,000 people -- in Africa, Europe and Southeast Asia.Worldwide, more men killed themselves than women, WHO said, with 7.5 suicide deaths per 100,000 women and 13.7 suicides per 100,000 men. The only countries where the suicide rate was estimated to be higher in women than men were Bangladesh, China, Lesotho, Morocco, and Myanmar."While 79% of the world's suicides occurred in low- and middle-income countries, high-income countries had the highest rate, at 11.5 per 100,000" people, WHO said."Nearly three times as many men as women die by suicide in high-income countries, in contrast to low- and middle-income countries, where the rate is more equal," the WHO statement said."Suicide was the second-leading cause of death among young people aged 15-29 years, after road injury. Among teens aged 15-19 years, suicide was the second-leading cause of death among girls (after maternal conditions) and the third-leading cause of death in boys, after road injury and interpersonal violence."WHO said one way to bring down the global suicide rate would be to limit access to pesticides, which -- along with hanging and firearms -- are the most common method of suicide. For example, in Sri Lanka, a series of bans on highly hazardous pesticides led to a 70% decrease in suicides, saving an estimated 93,000 lives from 1995 and 2015. Similarly, in South Korea, a ban on the herbicide paraquat was followed by a 50% decrease in suicide deaths from pesticide poisoning from 2011-2013.Other steps the WHO said have helped reduce suicides include educating the media on how to report responsibly on suicide, identifying people at risk early and helping young people build skills that help them cope with life stresses.World suicide prevention day is September 10. 2815

The father of a South Carolina fifth-grader who died last week after a fight at her elementary school is demanding answers over his daughter's death. 161

The EU27 has agreed that it will accept the UK's request for a #Brexit flextension until 31 January 2020. The decision is expected to be formalised through a written procedure.— Donald Tusk (@eucopresident) October 28, 2019 235

The acting head of Immigration and Customs Enforcement, Mark Morgan, provided some details Wednesday on plans to execute an operation targeting families who have gone through their legal proceedings."If you're here illegally, then you should be removed," Morgan told reporters during a call. "And in this case, that includes families."President Donald Trump tweeted Monday night that ICE was preparing to deport "millions" of undocumented immigrants next week, but he fell short of offering details. The vague announcement was striking, given the figure and the decision to disclose an operation prior to its execution.Morgan on Wednesday refrained from providing a time frame or details on the scope of the operation. The intent, Morgan said, is to deter migrants from coming to the US-Mexico border, and the operation is expected to include families who are on an expedited court docket. It remains unclear if the President was referring to this operation in his tweet.Last year, the Executive Office for Immigration Review, which oversees the nation's immigration courts, announced that it had begun tracking family cases filed by the Department of Homeland Security in 10 immigration court locations: Atlanta, Baltimore, Chicago, Denver, Houston, Los Angeles, Miami, New Orleans, New York and San Francisco.The cases are being expedited to try to process the families in under a year.Morgan said ICE had worked closely with the Department of Justice on the family expedited docket and that the "results were very disappointing." He claimed that some families haven't attended their immigration hearings, saying, "They're going through a thorough due process as part of the immigration process, they're just refusing to show up."Additionally, in February, ICE sent around 2,000 letters to families who already had received final orders of removal by judges in absentia, asking them to self-report to local ICE offices by March to comply with the orders, Morgan said.Morgan, who took over the director role in an acting capacity weeks ago, stressed that there hasn't been a shift in direction for the agency but rather a continuation of its policy not to exclude any demographic for arrest and deportation.CNN 2224