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SAN DIEGO (KGTV) - California’s Republicans are hoping to grow the party’s numbers in the state despite current odds.Roughly a quarter of California’s voters are registered Republican and in San Diego the GOP is seeing people jump ship.The San Diego GOP has lost thousands of voters in the last year with San Diego County Voter Registrar reporting 491,783 Republicans in May of 2018— compared to a little more 500,000 in May 2017.“A lot of that is the bullying or the stereotyping that goes on with being a conservative,” said Justin Clark, a 19-year-old conservative running for state assembly in Los Angeles, “you have a lot of people not wanting to identify as conservative, but a large portion of those 'undeclared to say' voters are.”The number of undeclared voters in San Diego is 476,186 in 2018 compared to approximately 461,000 just a year ago.“Whether your for or against the two-party system is irrelevant,” said Clark, “but its how those people feel. It’s why those decline to state numbers keep going up because they want to stay with them, they want to identify as them.”Among the California GOP’ers convening in San Diego the first weekend in May are other young faces.Morgan Murtaugh is a 25-year-old former news anchor running for Congress in California’s 53rd District, which is currently held by incumbent Democrat Susan Davis.Murtaugh says she’s gotten death threats over her conservative political leanings.“I mean my grandparents immigrated here from Mexico,” said Murtaugh, “I’m Mexican and I’m a woman. People look at me and they’re like ‘how are you identifying as a Republican they hate you?’ They don’t.”Murtaugh says she and other young Republicans are trying to break the stigma they say is a fabrication of the other side.“I want to change that assumption, said Murtaugh, “I want people to see that we can be for equal love, and we can be pro-environment. I really just hope we can get past these labels at some point.”There are 1.6 million registered voters in San Diego with more than 611,000 Democrats. 2043

SAN DIEGO (KGTV) -- Bail was set at million Thursday at an arraignment for the suspect in an officer-involved shooting in Logan Heights. Police say 30-year-old 170

SAN DIEGO (KGTV) - Anyone touched by Alzheimer's knows how painful the disease is. "It's affected my family. It's affected most families. It's such a prevalent disease. As people get older, it becomes quite likely this will become an issue," said Paul Aisen, director of USC's Alzheimer's Therapeutic Research Clinic (ACTC).Aisen's team began their research in San Diego many years ago and teamed up with USC about four years ago. He's spent over 30 years trying to solve Alzheimer's mysteries and is leading the upcoming clinical trial.Aisen says the large-scale study is the culmination of decades of work from scientists worldwide."Our focus lately has been trying to alter the disease, prevent it, or significantly slow its progression. How should we do that? We think attacking amyloid early is the most promising approach," said Aisen. Researchers believe sticky amyloid deposits, which form on the brain later in life, start the Alzheimer's process. Aging, genetics, and lifestyle factors can all contribute to amyloid build-up.The worldwide clinical trial aims to target amyloid. A drug called BAN2401 will be delivered intravenously, designed to bind to the sticky amyloid. The binding neutralizes beta amyloid and helps "tag" it, so the immune system can recognize it and clear it from the brain. A previous phase 2 study showed that BAN2401 removes brain amyloid and possibly slows cognitive decline.They're seeking participants over 50 who are not yet showing symptoms of Alzheimer's but do have elevated amounts of amyloid on their brain. Researchers can determine that through a PET scan or spinal tap. "We think that the most promising approach of all is to take a vigorous attack on amyloid while the brain is still functioning normally. And we can see amyloid in people many years before they develop the symptoms of Alzheimer's."Investigators hope that by treating a patient with BAN2401 very early in the disease, before symptoms occur, it will significantly slow disease progression. "If we're successful, it will have a huge impact on human health," said Aisen. There will be 100 sites worldwide for the study, including major cities like San Diego and Los Angeles. Study participants will receive treatment for four years, given either the drug or a placebo. Results are expected in seven years, Aisen says. If you or a loved one wants to participate, learn more here.Screening will officially begin in May. 2438

SAN DIEGO (KGTV) - At least one person is dead after a collision in Sorrento Valley early Saturday.A field of debris marked the site of the collision on northbound Interstate 5 at the I-805 connector. California Highway Patrol officers the crash included a white Toyota Tacoma and a red Honda.The driver of the Honda died at the scene. CHP officials said they believe that person was driving the wrong way and may have been under the influence of alcohol - multiple beer cans were found in the vehicle.The driver of the Toyota was taken to a nearby hospital with serious injuries. Officials said  He was in his truck with his dog at the time of the crash. The man's dog was taken to a nearby animal hospital, though its condition is not known.RELATED: Updating San Diego traffic conditionsA motorcycle seen in the wreckage was originally in the bed of the pickup truck, according to CHP officials.Three lanes on I-5 were shut down while crews investigate and clean up the scene 1010

SAN DIEGO (KGTV) — As the coronavirus pandemic has left many San Diegans in need.From hospitals to food banks to neighbors, there are plenty of ways to lend a hand.HOW TO HELPHospitals: Many local hospitals are reeling from the coronavirus pandemic, mainly with a lack of personal protection equipment. One way to support hospitals is to donate gear. Many San Diego hospitals are accepting donations for masks, gloves, eye wear, hand sanitizer, food, money, and more to support the health care industry at this time. LinkMany have also started making masks for health care workers. To help contribute, find out more.Blood donations are also in critical need. To donate blood, visit the Red Cross San Diego or San Diego Blood Blank.Seniors: There are a number of ways to help out local seniors who are under self-isolation during the coronavirus pandemic. One of the easiest ways is logging on to NextDoor and connecting with neighbors to talk or help out if they need a hand. LinkIn San Diego, locals can also help out Serving Seniors, a non-profit that delivers meals to low-income seniors, by making a dontion. LinkFood: Local food banks are also in need of support — food, money, and volunteers — to response to needy San Diegans during the COVID-19 pandemic. To make a donation to the San Diego Food Bank, click here.Restaurants: Local restaurants are some of the hardest hit businesses during the coronavirus pandemic. A simple way to help them out is to continue supporting them. The #TakeOutChallenge supports the campaign to continue eating at local establishments. LinkAs part of 10News' We're Open San Diego initiative, you can search for businesses that are remaining open and continue lending your support during this tough time. LinkSmall businesses/Nonprofits: The San Diego Foundation has set up a Community Response Fund to help local nonprofits, who can in turn support small businesses and individuals affected by the coronavirus. Individuals, businesses, and foundations can make monetary contributions to support the fund. To make a contribution, click here. 2086