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WASHINGTON, March 22 (Xinhua) -- A long-term study by Greek researchers has shown the effectiveness of replacing bone marrow, purposely destroyed by chemotherapy, with autologous (self) stem cells in treating people with aggressive forms of multiple sclerosis (MS).The study was published on Tuesday in Neurology, the medical journal of the American Academy of Neurology.For the treatment, chemotherapy drugs are used to kill all of the patient's blood cells, including the immune cells that are believed to be attacking the body's own central nervous system. Bone marrow stem cells removed from the patient are purified and transplanted back into the body, which saves life by replacing the blood cells and also is proposed to "reboot" the immune system.A human embryonic stem cell line derived at Stanford University is seen in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The study followed 35 people for an average of 11 years after transplant. The study involved people with rapidly progressive MS who had tried a number of other treatments for MS with little or no effect. All were severely disabled by the disease, with an average score of six on a scale of disease activity that ranges from zero being a normal neurological examination to 10 meaning death due to MS.A score of six means able to walk with a cane or crutch; a seven is mainly in a wheelchair. All had worsened by at least one point on the scale in the year prior to the transplant.After the transplants, the probability of participants having no worsening of their disease for 15 years was 25 percent. The probability was higher -- 44 percent -- for those who had active brain lesions, which are a sign of disease activity, at the time of the transplant.For 16 people, symptoms improved by an average of one point on the scale after the transplant, and the improvements lasted for an average of two years. The participants also had a reduction in the number and size of lesions in their brains. Two people (six percent) died from complications related to the transplant at two months and 2-1/2 years post-transplant.Study author Vasilios Kimiskidis, of Aristotle University in Thessaloniki, Greece, noted that more research is needed on this treatment, including studies that compare people receiving the treatment to a control group that does not receive the treatment."Keeping that in mind, our feeling is that stem cell transplants may benefit people with rapidly progressive MS," he said. "This is not a therapy for the general population of people with MS but should be reserved for aggressive cases that are still in the inflammatory phase of the disease."
BEIJING, March 17 (Xinhuanet) -- A new study has shown that gene therapy can reduce symptoms in patients with Parkinson's, media reports said Thursday.The study, published in the journal Lancet Neurology, is the first to show positive results in a test of gene therapy against a sham operation in 45 U.S. Parkinson's patients.The treated group showed a 23.1 percent improvement on a scale of Parkinson's symptoms six months after treatment, compared to a 12.7 percent improvement for patients who received sham surgery, according to the published research."Gene therapy is no longer just a theory," said Michael Kaplitt, a neurosurgeon at New York-Presbyterian Hospital and Weill Cornell Medical Center, and one of the study authors. "We are getting much closer to a reality where this treatment can be offered to patients."In patients with Parkinson's disease, their brains get overactive after losing the normal supply of a chemical called GABA. The new treatment, gene therapy, works by inserting billions of copies of a gene into patients' brains that helps them produce more GABA.Kaplitt said the results might spur similar treatments for other brain disorders like Alzheimer's, epilepsy and depression.
BEIJING, Jan. 19 (Xinhua) -- China's central government on Wednesday called on local authorities to step up efforts to ensure a stable market supply of daily necessities, such as food and clothing, as freezing weather continues to plague south and southwest China.The Ministry of Commerce required local government departments to guide companies to increase supplies such as rice, edible oil, meat and vegetables.It also required local departments to closely watch market changes and release reserves of commodities when necessary, said a statement on its website.The statement said the government of southwest China's Chongqing Municipality has urged local supermarkets to maintain the prices of 10 types of vegetables that are affordable to the public, while authorities in the rain and snow-battered Guizhou and Hunan provinces guided logistics companies and wholesales markets to take measures to insure supplies.The Ministry of Agriculture on Wednesday also ordered local departments to expand areas for growing vegetables when conditions allow, as agricultural experts were also sent to fields to help farmers save their crops.The country's meteorological authority forecast Wednesday that over the next three days, heavy snow and icy rain would continue in provinces and municipalities including Guizhou, Hubei, Hunan, Jiangxi, and Chongqing.
SYDNEY, Jan. 25 (Xinhua) -- Huawei Technologies, on Monday asked a U.S. District Court to prevent Motorola from illegally transferring Huawei's intellectual property (IP) to Nokia Siemens Networks ("NSN"), officials of Huawei told Xinhua in Sydney, Australia on Tuesday.As a leading player in providing next generation telecommunications network solutions, Huawei took this action as NSN seeks to complete its 1.2 billion U.S. dollars acquisition of Motorola's wireless network business.Since 2000, Huawei and Motorola have had a cooperative relationship in the radio access network and core network businesses, where Motorola has resold Huawei wireless network products to customers under the Motorola name. During this period, Motorola was provided with products and confidential Huawei IP developed by Huawei's team of more than 10,000 engineers.Since the July 2010 announcement by NSN of its purchase of Motorola's wireless network business, Huawei has tried to ensure that Motorola does not transfer this confidential information to NSN.According to officials of Huawei, Motorola's failure to adopt measures sufficient to ensure that Huawei's proprietary information remains confidential has compelled the company to file for the appropriate legal protection of its rights.The officials said Huawei respects the rights of intellectual property holders and is equally committed to the protection of its own innovations and intellectual property.Nearly half of Huawei's 100,000 plus employees are engaged in research and development and Huawei allocates an average of 10 percent of all revenues to R&D annually. By the end of 2010, Huawei had applied for 49,040 essential patents on a global basis.
LOS ANGELES, April 29 (Xinhua) -- Clinical and teaching microbiology laboratories are linked with a nationwide salmonella outbreak in the United States that has killed one person and sickened dozens of others, health officials confirmed on Friday.Since August, about 73 people in 35 states have been sickened by salmonella bacteria, and some of those cases involve a strain of Salmonella typhimurium sold commercially to laboratories, officials from the Centers for Disease Control and Prevention (CDC) said in remarks published by msnbc.com.Illnesses have been tied to laboratories from Alaska to New York, with most reporting one or two cases. Five cases have been reported in Washington state and four in Minnesota.The first illness occurred late August and the most recent cases were reported March 8, according to the CDC.The patients include employees and students of the laboratories, as well as children in the homes of people who work or study at the labs.Patients ranged in age from less than one to 91, with a median age of 24, the CDC said.Cases that developed after March 19 may not yet be included in the total because of the lag time in assessing and reporting illness, said the report.CDC officials warned that bacteria used in the labs can be transmitted through contaminated lab coats, pens, notebooks, car keys and other items brought into the labs.The CDC is working with local and state health departments, the American Society for Microbiology and the Association of Public Health Laboratories to track the outbreak, the report said.Salmonella infections typically result in diarrhea, fever and abdominal cramps. They can be dangerous in very young children or people with compromised immune systems.