濮阳东方医院男科治疗早泄很不错(濮阳东方妇科医院好不好) (今日更新中)

SAN DIEGO (KGTV) — The back-to-back announcements of promising clinical trial results from Pfizer and Moderna may usher in a new era for vaccine technology.Both companies have candidates that rely on a new kind of vaccine strategy: RNA. Preliminary data show both candidates are more than 90 percent effective.On the surface, the vaccine candidates look like any other you’ve taken. They work by training your body to build up defensive weapons against a virus, like antibodies and T-cells.But instead of training your body by introducing a killed virus or a fragment of a virus, the vaccines from Moderna and Pfizer introduce a set of instructions called messenger RNA enclosed in a little blob of fat.“The key concept of RNA is that they’re messages, and they’re meant as short-term messages,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.Crotty said there are 5,000 to 10,000 messages within a cell at any given time.Once administered, the mRNA in the vaccine instructs some of your cells to make the coronavirus’ signature spike protein. The spike protein on the surface of the coronavirus allows it to infiltrate and hijack cells.Even though the spike protein is just one of about 25 genes the virus has, preliminary results from the clinical trials suggest it is enough material to train the immune system without making the recipient sick.Crotty likened the process of training the immune system to spotting a sedan. If the coronavirus is a car, the spike protein might be the door.“There's no way that car door could turn into a whole car, but it's enough of a piece of a car for your immune system to recognize that car if it saw it again,” he said.Scientists started by sequencing the virus’ DNA from a sick patient, then encoding that genetic sequence into an mRNA instruction molecule that can be read by the manufacturing part of cells.From there, Dr. Crotty said it’s a bit like the messenger app Snapchat.The mRNA gets injected into the body, sending temporary instructions to your cells that last for a while, then disappear. mRNA does not genetically modify cells, he stressed.“They’re around as messages for some period of time and then they go away, and the cells get back to their normal job of reading their own messages instead of reading the messages you’re injecting in the vaccine,” he said.The concept has been around since the 1990s, but there are currently no RNA vaccines on the market for any pathogen, so Dr. Crotty said it’s hard to estimate how long their protective effects will last.Some vaccines offer a lifetime of protection, like the measles vaccine. Others offer decades of protection. The flu vaccine only lasts about six months.Dr. Crotty said the length of protection depends on how fast the virus mutates and how long the immune cells survive in the body.But even if the COVID-19 vaccine turns out to need an annual update, he’s optimistic. The best feature of RNA vaccines is that they can be quickly reprogrammed.Both Moderna and Pfizer are still in their Phase 3 trials, but they expect to finish them by December. Together, they estimate they’ll have enough doses for about 35 million people by the end of this year, primarily for healthcare workers and high-risk individuals. 3250

SAN DIEGO (KGTV) -- Technical problems at the state level impacted the California Department of Public Health's ability to accurately report COVID-19 cases."We are committed to the medium- and long-term to address these foundational data issues so that we can approve our importance and our customer service," California Gov. Gavin Newsom said on Monday.According to the state, the data system they use failed, and that led to inaccurate case numbers and case positivity rates. That failure prevented counties from having some of the data they need to monitor and respond to the virus in local communities, such as contact tracing.The state says that about two weeks ago, a server outage created a delay in lab records coming into the reporting system. At the same time, they realized they weren't getting data from one of the largest commercial reporting labs for about five days."Just thanking all Californians for their patience as we continue to make sure we're sharing this accurate COVID-19 data," said Secretary of California Health and Human Services Dr. Mark Ghaly. "We know how critical it is for planning at the local level for all Californians to feel confident about the trends and where we're heading."Counties across the state felt the impact of the data inaccuracies. Local leaders use numbers and science to guide decision-making.But are counties having any issues with the numbers at the local level?In Kern County, public health officials were asked at the end of July if they're 100% sure no one is getting double-counted for positive COVID-19 tests."That answer would be no…we do get cases that we hear that their addresses are mismatched, they've been counted in another county, they were tested and are in another county, and we are still waiting for that information to flow through so I'm not comfortable saying that we're 100% sure that we aren't duplicating any cases," Kern County Public Health Department Lead Epidemiologist Kim Hernandez said.Public health said less than 18.4 cases were reported inaccurately.Kern County Chief Administrative Officer Ryan Alsop told 23ABC News, "The data and duplication that you are asking about is not a reason we are on the state’s monitoring list."With questions about accuracy at the state level and those raised in Kern County, reporter Adam Racusin asked officials in San Diego and San Luis Obispo counties how confident they are in the daily numbers they report to the public."I'm quite confident our numbers are accurate," said San Diego County Public Health Officer Dr. Wilma Wooten. "We have web CMR, and our tests are not all phoned through CalREDIE system. Our test results are reported directly to the county. The only issue which you already know about is the glitch with Quest."A spokesperson for San Luis Obispo County said they are confident in the number of positive cases reported.A spokesperson for the county said, "When it comes to duplicates, they regularly run data queries on positive case results to search for duplicates. On occasion duplicates have been detected and counts adjusted appropriately."The spokesperson also noted, "With regard to the total number of tests (positive and negative), some individuals may receive multiple tests over time. We do not classify those as duplicates but rather they are counted as distinct testing events. That is to say, if one is tested five times, that will show with five distinct test results. All that said, some locations/labs are not reporting ALL their test results (both negative and positive) through our reporting system. Some are only reporting positive tests. So, there may be some under-reporting of negative tests. Consequently, we are confident that the number of positive case reports is correct, although the number of negative results (and by extension) the number of total tests run, may be somewhat under reported."The California Department of Public Health did not respond to multiple requests for comment about data accuracy and duplicate counting. 4011

SAN DIEGO (KGTV) - The California Attorney General’s office sent a warning to HiCaliber Horse Rescue in Valley Center, days after a Team 10 investigation into the group’s practices.The rescue is delinquent with the Registry of Charitable Trusts for failing, in part, to submit its 2016 taxes, according to the Attorney General’s office.HiCaliber told Team 10 investigator Jennifer Kastner it was honest mistake that’s being addressed.RELATED: Questions of fraud and abuse at prominent horse rescueThe group told 10News it received an extension on its 2016 taxes because of a personal emergency.The rescue recently came under fire for euthanasia and questionable fundraising practices. 692

SAN DIEGO (KGTV) - Teachers are quickly adapting to online lesson plans to engage their students.Third grade teacher Carlisa Flanders said Friday was the first day she'd been back to school since Grant K-8 shut its doors March 13 due to coronavirus concerns.Flanders said the day the school closed was hectic and stressful, "we had a couple hours to hussle. I put together two weeks of work, took as much as I could went home and hunkered down."She was emotional thinking of the future, wondering when she was going to see her students again and when school would reopen.Tuesday was the day she was able to go online, using a program called Zoom, and video conference with her students. She said 18 of the 21 students have been attending school this week.Friday morning, their homework assignment was to bring one thing to share. Many of her students showed off their pets."The majority of my focus is going to be making sure I stay connected with my students, making sure they feel the love," she said, gesturing at a board behind her with the words, 'Good Morning! You are awesome! You are loved!' written in different colored markers.Flanders said right now class is optional and labeled as enrichment. She said Thursday she read a book to the kids.Parents, like mom Leona Smith, said the social interaction from class is exactly what her son has been missing, "that connection he has, and the bonds that he has with his friends and his teacher it's like no other.""I think we forget how much school and their friends and their teachers are part of their everyday life," Smith said.Mrs. Flanders has been working tirelessly to bridge boundaries with online education, "I am now texting, communicating with friends I now have in Georgia, in Texas, in Oregon who are also third grade teachers and I'm collaborating virtually with strangers but their hearts are in the exact same place as mine and we're all just like try this, try this, try this."She said her tech savvy students are also stepping up teaching her tricks, like starting a chat and sharing pictures through the program. 'Our first lesson was how to mute and unmute the microphone,' Mrs. Flanders said.Friday was emotional. Mrs. Flanders said she was glad to go back to school and see fellow teachers' cars in the parking lot, but could only wave hello from a distance. "I got to go back to school for 20 minutes, I got my charts, I got our class mascot, this is happy," she said holding a rainbow hedgehog stuffed animal. She said she also grabbed a large stack of books.She was also happy to get back a semblance of a routine, saying class will start online officially on April 27."Oh gosh, it's mind boggling to think how these grades will actually count towards them finishing the third grade year," Mrs. Flanders said concerned.She's focusing instead on each lesson and the positive impact she can make on her students."At the end of every school day I usually hug, high-five or fist bump my kids, so our first Zoom, we decided this is our new way of hugging," She said making an 'air-hug' gesture, "So to all of you here's a hug. We'll get through this."The San Diego Unified School District said schools will be soft launching online education April 6. That way they can connect students in need with computers and WiFi, so everyone is ready for the hard launch April 27. That means teachers will assign tasks that will be graded.The district said if a student cannot connect online, they will not be penalized and their grade will be frozen. 3523

SAN DIEGO (KGTV) - The Food and Drug Administration has recalled several types of tattoo ink after determining they were contaminated with bacteria. One of them is the popular black ink made by Dynamic Color. The FDA found that two of their lots tested positive for microorganisms. The recall includes all bottles of Scalpaink SC, Scalpaink PA, and Scalpaink AL basic black tattoo inks manufactured by Scalp Aesthetics. One lot of Color Art’s red Solid Ink-Diablo was also included. Tattoo shops across the country were contacted through their local health departments about the recall. One of the largest tattoo parlors in San Diego, SD Tattoo, says they got the email Wednesday morning and immediately searched through their inks.They did have the Dynamic black ink, but tattoo artist Nicki Ninteman said, "We checked all the lot numbers and all of ours are clean, so we’re good."She said they didn't have either of the other two brands in the shop.According to the FDA, people who have been tattooed with contaminated ink can experience rashes or lesions of red papules. If untreated, contaminated ink can also cause permanent scarring. For more information one the FDA recall, visit their website. 1209

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