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The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722

The U.S. has now seen two straight weeks in which at least 100,000 people are confirmed to have contracted COVID-19 each day.On Monday, the U.S. reported 166,000 new cases of the virus, marking the 14th consecutive day with 100,000 or more new cases of the virus, according to a database kept by Johns Hopkins University.The last day new cases totaled less than 100,000 was on Nov. 2. Since then, about 1.9 million Americans have contracted the virus, the rolling 7-day average of hospitalizations across the country has increased from 50,000 to 65,000 and daily deaths on a rolling 7-day average have ticked up from 824 a day to 1,114 a day.That 14-day time span has also seen seven days in which record numbers of new cases were reported. The current record was set on Friday when 177,000 people in the U.S. were confirmed to have contracted COVID-19.The current spike in caseloads has led hospitals across the country to become inundated with patients, overwhelming resources. The COVID Tracking Project reports that most of those hospitalizations are occurring in the Midwest, where rural hospitals in places like Iowa and South Dakota are running short on bed space.The current standard was predicted in June by Dr. Anthony Fauci, the nation's highest-ranking infectious disease expert. During a Senate hearing, Fauci stunned lawmakers by predicting that the U.S. could reach a point where 100,000 people were being infected each day if "disturbing trends" continued.Fauci's comments in June came during a summer spike in cases which saw infection rates top out at about 77,000 new cases each day.The current spike in cases comes as drugmakers like Pfizer and Moderna have reported encouraging results in vaccine trial results. While both vaccine candidates are on track for Emergency Use Authorization by the end of 2020, the drug likely won't be widely available to the general public for several months — Fauci has predicted that a vaccine will be widely available in the U.S. by April. 2002

The St. Louis Police Department is investigating one of their own after he issued a ticket to a man who honked at him.According to an interview in the Riverfront Times, Scott Smith was on his way back to work when he honked at a car stopped at a green light. Video shot by the driver and given to the RFT shows a very tense interaction.The car was an unmarked police car. When pulled over, Smith says "seriously?"The officer than replies "Seriously, is your horn stuck?" to which Smith replies "Is your brake stuck?"That's when the officer cusses at the driver asking again "Is your f-ing horn stuck?"He demands to see his driver's license.Smith says he will, but asks for what."I'll tell you what, you can either show your driver's license or you'll get a ticket and I'll tow your car and lock you up," said the officer.Once again Smith asks why he's been pulled over and the officer says it is for a traffic violation."For honking at someone who's stopped at a green light?" Smith asks. He then calls the situation "f-ing ridiculous." "Well you know what? Maybe you shouldn't be a f-ing a-hole," the officer responds.The officer issued the driver a ticket, but the city counselor's office reportedly will not prosecute it, saying they do not believe it should be pursued."The Department has launched an Internal Affairs investigation into the incident you are inquiring about. At this point, it would be premature for the Department to comment on an ongoing investigation before it concludes," a St. Louis Police spokesperson said.  1557

The Vatican released a letter Monday from Pope Francis directly addressing for the first time the latest accusations of sexual abuse by priests. Here is the full text of the letter. 189

The United States Army has announced the Guillen family is entitled to receive a variety of Army benefits after Spc. Vanessa Guillen's death was determined to be "in the line of duty."Army officials say the Guillen family was briefed on Tuesday, October 20 on the results of the line of duty investigation into Spc. Guillen's death.The investigation concluded that her death was in the line of duty. This determination allows the Guillen family to receive Army benefits due to Spc. Guillen's service.The Army says these benefits typically include compensation to immediately help the family with expenses, a funeral with full military honors, the Servicemembers’ Group Life Insurance, and final pay and allowances.A line of duty determination is conducted for all soldier deaths.Officials say the III Corps leadership remains in contact with the Guillen family to keep them informed of the additional actions being taken at Fort Hood, and what policies are being revised to ensure Army culture continues to put people first and honors Spc. Guillen's life.This story was first reported by Sydney Isenberg at KXXV in Waco, Texas. 1135

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