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SAN DIEGO (KGTV) -- Deadly crashes rose in San Diego in 2018, according to a new report by the National Highway Traffic Safety Administration. According to the report, there were 240 deadly crashes in San Diego County in 2018.In 2017, 223 deadly crashes were reported countywide, the agency said. According to the data, January and July were the deadliest months in 2018, each with 28 fatal crashes. RELATED: San Diego rain could lead to more crashes on wet roadsThe month with the least fatalities was May in 2018. The report didn’t specify why exactly certain months had more deadly crashes than others. The U.S. as a whole, however, saw fewer deadly crashes, showing a 2.4 percent decline from 37,473 in 2017 to 36,560.The agency says 2018 marked the second year in a row of reduced crash fatalities. RELATED: San Diego not the worst US city to drive in, but not the best either“This is encouraging news, but still far too many perished or were injured, and nearly all crashes are preventable, so much more work remains to be done to make America’s roads safer for everyone,” U.S. Transportation Secretary Elaine L. Chao said. Also promising: the data show that deadly crashes among children 14 and younger declined more than 10 percent while alcohol-impaired driving fatalities decreased 3.6 percent. 1313

SAN DIEGO (KGTV) -- As coronavirus cases increase across the country, there is a concern about staffing in hospitals across Southern California.Not only are hospitals dealing with patients they typically see during this time of year, COVID-19 patients are adding stress to thinning resources.“If these trends continue, we’re going to have to much more dramatic—arguably drastic—action,” said Governor Gavin Newsom during a news conference on Monday.Currently, 74 percent of ICU beds are occupied in Southern California. State health officials protect it to be at 107 percent capacity by December 24th.“I have a guarded concern about the direction that we’re moving in,” said nurse practitioner Samantha Gambles Farr of the rising cases.Gambles Farr said she is not only worried about staffing numbers, but also the physical and mental health of her colleagues. “The staffing issues have always been something that we've dealt with in the ICU because of the critical acuteness of our patients and the burnout of staff,” she said. ‘In these unprecedented times with COVID in the pandemic, what we're seeing is that nurses are picking up a lot more overtime and shifts.”Early in the pandemic, the state created the California Health Corps. It asked for those with health care experience to help during the COVID-19 outbreak. Thousands, including retired workers and nursing students, volunteered to help. However, only 900 people are currently ready to be deployed, according to a recent story by the Sacramento Bee.In New York. Governor Andrew Cuomo has already asked for help from retired health care workers.“It’s not like we can then call on our colleagues from another state to help us because they’re dealing with the exact same issue,” Gambles Farr said. 1766

SAN DIEGO (KGTV) - California ranked first in the U.S. for most fun states in a WalletHub survey.States were evaluated on factors that make fun a way of life. The top states offered a variety of activities for everyone to find a source of enjoyment.Cost was a consideration, too. WalletHub compared states for indicators of a good time that isn’t too expensive.Here’s how California breaks down, per capita: 415

SAN DIEGO (KGTV) — As the elderly population is told to stay home to protect themselves from coronavirus, a group like ElderHelp is necessary. ElderHelp has been helping seniors with anything from giving rides to grocery shopping for decades. Now, they have adapted to COVID-19 restrictions, with a system where volunteers pick up groceries from the nonprofit's hub, then drive the food and supplies to the seniors’ homes to deliver without contact.ElderHelp has seen a 773% increase in requests for service since the pandemic began and now completes 522 deliveries on average every week.Carol Greene is one of the seniors who has food delivered to her San Diego home and said the communication with the staff brightens her days.“I look at ElderHelp as all the sunshine. You might be at home on your normal, boring day at times and whoop there’s the phone,” she said.They just received a 0,000 grant from the San Diego Foundation but say they are still always in need of both donations and volunteers, especially in light of the recent increase in demand.Nicole Darling has been volunteering with ElderHelp since 2003 and said the seniors appreciate the food, but always seem to enjoy the interaction as well, especially during a time of isolation.“It’s a small amount of effort to make a huge amount of good for people who are really vulnerable and alone,” said Darling. 1382

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

来源：资阳报