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JOHANNESBURG (AP) — Health authorities are poised to declare the African continent free of the wild poliovirus after decades of effort. The declaration on Tuesday leaves Pakistan and neighboring Afghanistan as the only countries thought to still have the wild poliovirus. "Today we are also celebrating another public health triumph: the eradication of wild poliovirus in Africa," said Director-General Dr. Tedros Adhanom Ghebreyesus with the World Health Organization. "This is an incredible achievement, and a much-needed cause for celebration."The World Health Organization says this is just the second time a virus has been eradicated in Africa, after smallpox four decades ago. However, the announcement doesn’t mean Africa is polio-free. Cases of vaccine-derived polio are still sparking outbreaks. Still, health authorities see the declaration as a rare glint of good news in Africa amid the coronavirus pandemic and another Ebola outbreak in Congo that has infected 100 people. 993

Kevin Costner is well on his way to becoming Montana's state mascot.With three seasons of "Yellowstone" under his rusty belt buckle, he's back in the Big Sky State in "Let Him Go," playing a similarly tough rancher. Having reinvented himself as a Great Plains tough guy who speaks softly and hits hard, he simmers with a steadfast self-confidence molded into latent angst that he lets surface up at key times.In the film, he plays George Blackledge, a former lawman who has retired to his Montana ranch along with his wife, Margaret (Diane Lane). Their grown son dies, leading their daughter-in-law to run off with their grandson in search of a new life with an abusive husband who is part of a notorious family of criminals. Not content to let that slide, they set off on a hunt for their grandchild, pickup truck, and pistols at the ready.Costner, who is in top form, finds an excellent partner in Lane, who shows a hard-edged exterior that shelters a heart filled with courage and compassion. Margaret and George are the adorable older couple next door who happens to be up for cross-country road trips with trespassing and shootouts on the agenda.Danger lurks around every corner, but the couple relies on their experience and boldness to power through, using their wits to outmatch their ruthless opponents.They also fight among themselves. Margaret calls George out on his macho bravado and shows a savvy for dangerous situations that he seems to lack. Watching the characters operate together, informed by decades of marriage, is one of the film's joys.Director Thomas Bezucha, who is best known for the lighthearted rom-com "The Family Stone," shows a deft dramatic touch here, with a slow-burn drama that recovers from a lazy start to evolve into a suspense-packed thriller.With strong supporting roles from the likes of Booboo Stewart, Lesley Manville, and Will Brittain, "Let Him Go" is a solid, Golden Years revenge fantasy that filled with thrills and sticks to your ribs. If Costner keeps making TV and films as strong as this, he shouldn't let this Montana passion go.RATING: 3 stars out of 4.Phil Villarreal TwitterPhil Villarreal FacebookPhil Villarreal Amazon Author PagePhil Villarreal Rotten Tomatoes 2228

Just weeks ahead of the midterm elections, U.S. election databases are coming under attack.A new report finds election hacking attempts have been building since April. One troubling note: the government does not know who is behind the attacks.“Well, it is worrisome. The more we know, the better,” says John Fortier, with the Bipartisan Policy Center. “But I also do think, in the world that we have, we are going to have unknown actors, whether foreign or domestic, making attempts to get into systems.”The good news is that, so far, Homeland Security says none of the attacks have been successful.Fortier thinks that's a sign of enhanced election security and better communication between election officials.“I think we are in a better place now to identify those threats and communicate those threats between federal and local and state election officials, and I think that's a step up,” Fortier says.As the midterms approach, the head of Homeland Security says the government will also be using other security tools, including sensors that allow federal officials to see inside state computer systems in order to detect if there are signs of hacking attempts.“Our network security sensors will cover 90 percent of registered voters,” says Secretary of Homeland Security Kirstjen Nielsen. “And on election day, we'll be in full force and hosting a virtual nationwide situation room to assist our partners.Experts continue to insist that voter databases, like registration information, is more at risk than hackers being able to change actual votes. 1559

Kentucky's statewide primary is Tuesday, and those wanting to vote in person could be in for a long wait. Louisville and Lexington, the state's two largest cities, each have only one in-person polling location.The state's primary was postponed more than a month because of the coronavirus pandemic, and elections officials allowed all voters to vote by mail using absentee ballots. They have also cut down the list of in-person voting locations to just 170 statewide. According to the Kentucky secretary of state, they typically have around 3,700 polling locations. The changes have prompted responses from politicians, celebrities and activists who accuse the state of voter suppression. 697

LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871

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