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Moderna is asking American regulators to allow emergency use of its COVID-19 vaccine. It says its final results show the vaccine is 94% effective.The drug maker says it had 196 COVID-19 cases so far in its study. It says 185 of those participants received the placebo, while 11 got the real vaccine. The 30 people who became seriously ill in the trial didn't get the vaccine.FDA advisors are expected to look at all the evidence on December 17. They'll be checking out Pfizer’s vaccine on December 10.Pfizer and Moderna's success with their COVID-19 trials could impact how vaccines are made in the future.It has to do with how they work. They use what's called messenger RNA (mRNA) technology. The virus' genetic code is injected into the body so it can instruct cells on what antibodies to produce.It hasn't been approved to be used in a commercial vaccine before.“In the future, it's clearly going to be tough to beat RNA vaccines for speed and that's a wonderful thing. Just this demonstration of how incredibly fast they can move has been great. How effective they can be, I think will depend on a particular disease,” said Shane Crotty, Ph.D. with the La Jolla Institute for Immunology.Crotty says the narrowest application for this vaccine technology in the future is a similar situation where there's a new emerging virus."The mRNA vaccine has been tried for other infectious diseases and they have been investigated for cancer. There's a whole area of trying to vaccine against cancer, which has kind of been an elusive target,” said Dr. Alessandro Sette with the La Jolla Institute for Immunology.A big question with an mRNA vaccine is how long its protection will last. While there is encouraging findings, there's no historical comparison to look at.A big thing experts say has helped with a vaccine is there has been a lot of money put towards manufacturing before we even knew it would work.Click here to learn more about mRNA vaccines. 1958

NASHVILLE, Tenn. (AP) -- Comedian D.L. Hughley announced he's tested positive for COVID-19, following his collapse onstage during a performance in Nashville, Tennessee.In a video posted to Twitter on Saturday, Hughley said he was tested while being treated for exhaustion and dehydration after passing out at Zanies on Friday.He said the COVID-19 diagnosis was surprising because he was otherwise asymptomatic. He plans to quarantine in his Nashville hotel room for 14 days.The rest of the 57-year-old's shows at the Zanies club were canceled.In addition to stand-up comedy, Hughley is an actor, author and television and radio host. 641

More than 228,000 pounds of Hormel Spam and other canned meat products are being recalled because they might contain shards of metal, according to the US Department of Agriculture.The department's Food Safety Inspection Service said Saturday that the problem was discovered after four customers complained of metal objects in canned Hormel products. The FSIS did not say how the pieces of metal might have gotten into the products.Throughout the US, 12-ounce metal cans labeled "SPAM Classic" with the designation "EST. 199N" should not be eaten because of a risk of minor oral injuries, FSIS said. The cans have a "Best By" date of February 2021 and carry the following production codes: F020881, F020882, F020883, F020884, F020885, F020886, F020887, F020888 and F020889.Possibly contaminated cans of meat were also distributed in Guam. These 12-ounce metal cans contain "Hormel Food Black-Label Luncheon Loaf." The recalled cans are marked "Best By" February 2021 and carry the production codes F02098 and F02108.The products should be immediately thrown away or returned to the place of purchase, FSIS said. In a statement, Hormel said it was recalling the products "out of an abundance of caution," and that "the health and safety of consumers is our top concern."In 2016, Hormel voluntarily recalled 40 cases of Dinty Moore Beef Stew -- also because of possible contamination by "extraneous materials."The US-based Hormel Foods Corporation sells products in more than 70 countries. 1504

MILWAUKEE -- Six cars were damaged Friday when light poles fell across traffic lanes on I-43 near Milwaukee.According to the Milwaukee County Sheriff's Office, the driver of a red pick-up truck heading northbound hit both of the light poles in the median just before 3:30 p.m. A witness at a law firm off Hampton Avenue said she saw the truck drive up onto the median and hit one pole, before continuing on to hit a second. "Unfortunately one of them kind of struck the side of the car, put a hole in the door, took a mirror out," said Jim Lovering, whose daughter called him after swerving to avoid the two poles.Lovering's 7-month-old grandson was also in the car. "Just missed the windshield, which was a blessing," said Lovering. The camera caught deputies taking away the driver of the red truck in handcuffs. Authorities have not yet released any information confirming an arrest, or possible charges. The accident caused backups for miles during rush hour, as crews worked to remove the poles from the roadway. No one in any of the cars was injured. "It was just nice that she had the space to maneuver and without hitting anybody else or causing any further damage," said Lovering. "It could be potentially you know a serious accident. Thank God it didn't happen."  1341

National security adviser H.R. McMaster has agreed to resign and will be replaced by former US ambassador and Fox News analyst John Bolton, President Donald Trump announced in a tweet on Thursday."I pleased to announce that, effective 4/9/18, @AmbJohnBolton will be my new National Security Advisor. I am very thankful for the service of General H.R. McMaster who has done an outstanding job & will always remain my friend. There will be an official contact handover on 4/19.""The two have been discussing this for some time. The timeline was expedited as they both felt it was important to have the new team in place, instead of constant speculation," a White House official said. "This was not related to any one moment or incident, rather it was the result of ongoing conversations between the two."Bolton is a stalwart of Republican national security circles known for his hawkish views."After 34 years of service to our nation, I am requesting retirement from the U.S. Army effective this summer after which I will leave public service. Throughout my career it has been my greatest privilege to serve alongside extraordinary servicemembers and dedicated civilians," McMaster said in a statement released by the White House."I am thankful to President Donald J. Trump for the opportunity to serve him and our nation as national security advisor. I am grateful for the friendship and support of the members of the National Security Council who worked together to provide the President with the best options to protect and advance our national interests," the statement said. 1589

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