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WASHINGTON, March 4 (Xinhua) -- New data suggest that the epilepsy drug Topamax (topiramate) and its generic versions increase the risk for the birth defects cleft lip and cleft palate in babies born to women who use the medication during pregnancy, the U.S. Food and Drug Administration (FDA) said Friday in a statement.Before prescribing topiramate, approved to treat certain types of seizures in people who have epilepsy, health care professionals should warn patients of childbearing age about the potential hazard to the fetus if a woman becomes pregnant while using the drug, the FDA said.Topiramate also is approved to prevent migraine headaches, but not to relieve the pain of migraines."Health care professionals should carefully consider the benefits and risks of topiramate when prescribing it to women of childbearing age," said Russell Katz, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Alternative medications that have a lower risk of birth defects should be considered."Cleft lip and cleft palate, collectively called oral clefts, are birth defects that occur when parts of the lip or palate do not completely fuse together early in the first trimester of pregnancy, a time when many women do not know they are pregnant.The defects range from a small notch in the lip to a groove that runs into the roof of the mouth and nose, possibly leading to problems with eating, talking, and to ear infections. Surgery often is performed to close the lip and palate and most children do well after treatment.Data from the North American Antiepileptic Drug (AED) Pregnancy Registry indicate an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy. Infants exposed to topiramate as a single therapy experienced a 1.4 percent prevalence of oral clefts, compared with a prevalence of 0.38 percent - 0.55 percent in infants exposed to other antiepileptic drugs.Infants of mothers who did not have epilepsy and were not being treated with other antiepileptic drugs had a prevalence of 0.07 percent. Similar data from the United Kingdom Epilepsy and Pregnancy Register supported the North American AED Pregnancy Registry data.According to the FDA, before starting topiramate, pregnant women and women of childbearing potential should discuss other treatment options with their health care professional.

JOHANNESBURG, March 23 (Xinhua) -- Cervical cancer ranks as the second most frequent cancer among women in South Africa.Recent information from a World Health Organization (WHO) and ICO Information Center on Human Papilloma virus (HPV) and Cervical Cancer 2010 report shows that 16.84 million South African women aged 15 years and older are at risk of developing cervical cancer.Current estimates indicate that every year 5,743 women are diagnosed with cervical cancer and more than 3,000 die from the disease.About 21 percent of women in the general South African population are estimated to harbor cervical HPV infection at any given time, and 62.8 percent of invasive cervical cancers are attributed to HPV subtypes 16 or 18."Concern is growing as there appears to be an increasing epidemic of papillomavirus-induced disease involving not only the cervix but elsewhere in the female genital tract and anogenital region," said Professor Martin Hale, head of the Department of Anatomical Pathology at the University of the Witwatersrand (Wits) in Johannesburg and the National Health Laboratory Service.The South African population and people from Africa in general have high incidences of the HPV subtypes 16 or 18 according to Professor Hale. He is not entirely sure why but is of the opinion that the infection rate can be lowered."The common theory is that HPV is transmitted through sexual intercourse. If treated like a sexual disease and the necessary precautions are taken during sex the infection rate can be lowered, " Hale told Xinhua in an interview on Wednesday.HPV is also exacerbated as a result of the HIV pandemic and cause a rapid progression of premalignant dysplasia to invasive cancer in HIV positive patients.Hale believes the limited access to information and resources make it easy for the condition to thrive.However, according to Hale, a debate is still raging on how, to whom and whether the vaccine should be administered.Black women are at higher risk of contracting HPV and subsequent cervical cancer. Other risk factors that increase susceptibility include age of first intercourse, the number of children per woman, and a weakened immune system, to name a few."To avoid getting cervical cancer get the vaccine against HPV 16 and 18 infection before starting to be sexually active, have protected sex and go for regular screenings," he told Xinhua.

YANGON, May 6 (Xinhua) -- A five-day Myanmar traditional medicine exhibition is underway in Myanmar's former capital of Yangon beginning Thursday, aimed at promoting the development of the country's traditional medicines and disseminating medical knowledge to the public.With over 120 booths, traditional medicine producing companies are displaying their traditional medicine products and producing accessories as well as giving traditional treating service and medical education talks.As the Myanmar traditional medicine is playing a more and more important role in treating diseases in the country, the government urges traditional medicine practitioners to protect and preserve them from depletion and extinction and to ensure their perpetual existence.Myanmar is conducting research on treatment of major diseases -- diabetes, hypertension, malaria, tuberculosis, diarrhea and dysentery through traditional medicine.To do research more effectively and on a wider scale to have the Myanmar traditional medicine standardized, the country holds traditional medicine practitioners conference every year to introduce the country's traditional medicines and its medical practices and the last conference, which was the 11th, took place in Nay Pyi Taw in December 2010.At the same time, the practitioners are also urged to strive for the promotion of the standard of Myanmar traditional medicine to reach international level.

BEIJING, Feb. 14 (Xinhua) -- Chinese President Hu Jintao met with delegates from the national Party building society here Monday.Vice president Xi Jinping and He Guoqiang, secretary of the Central Commission for Discipline Inspection (CCDI) of the Communist Party of China (CPC), were also present at the occasion in the Great Hall of the People.The delegates were here to attend the fifth national congress of the national Party building society which was established in 1992.Addressing the meeting Monday, Li Yuanchao, head of the Organization Department of the CPC Central Committee, called on all the party building research staff to keep focusing on their study and be innovative in thinking about party building theory so as to strengthen party building in a more scientific way.The society revised its constitution and re-elected members of its council at Monday's meeting.

SAN FRANCISCO, April 8 (Xinhua) -- YouTube on Friday launched YouTube Live, a homepage for live content on the site and a new live-streaming platform.As part of the service, the world's largest video-sharing website introduced a new browse page, www.youtube.com/live, where users can view live events and add upcoming events to their calendars.YouTube said it would gradually roll out a live streaming beta platform, which will allow certain YouTube partners with accounts to stream live content on the website.The new service will "integrate live streaming capabilities and discovery tools directly into the YouTube platform for the first time," YouTube said in a blog post.U.S. media recently reported that YouTube is planning a major overhaul and is negotiating with Hollywood and music producers for materials to offer on a lineup of new channels, with the aim to compete with broadcast and cable television.

来源：资阳报