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Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

Happy Bobby Bonilla Day, New York Mets fans.The former major league baseball player gets a check for nearly .2 million Mets every July 1.Not a bad retirement plan.Under his contract, he gets the check every year until 2035, when he'll be 72.The Mets wanted to part ways with Bonilla in 1999, but he still had million left on his contract.Mets owner Fred Wilpon negotiated a deal to defer payments until 2011, followed by the annual payments, plus, an 8% annual interest rate.Why the deferment?So the Mets could invest the money with now-disgraced financier Bernie Madoff for a big return.But it turned out Madoff was running the most notorious Ponzi scheme in history, and the Mets ended up among the victims.In total, Bonilla will end up with .8 million because of Wilpon's huge bad call.And in 2012, Wilpon paid 2 million to Madoff victims' fund after auditors found he actually profited from the Ponzi scheme. 931

Harmless Halloween decor or something more?Residents in a Phoenix neighborhood say they were alarmed to see their neighbor's display featuring four bloodied sheets hanging from a tree with nooses around the necks.One woman said she's offended by the decorations and feels they are extremely inappropriate."My most generous assessment is that it is a defiant, very racist act to make people feel unwelcome in this community, and it's heartbreaking," neighbor Amanda Gilmore said.Phoenix-based KNXV spoke to the homeowner, who said the decorations were simply up for a Halloween party and he did not anticipate the reactions from his neighbors. He took down the display after hearing the objections. 720

From the value meals and dollar menus, fast-food restaurants know how to do it fast and cheap. However, over the past decade, prices have been slowly going up.Datassential, a research company studying restaurant menu trends, found median fast-food hamburger prices have jumped by 54 percent.   At McDonald’s, a Double Quarter Pounder with Cheese meal will cost you almost . At Burger King, the Ultimate Bacon Cheeseburger meal is almost . So, what’s behind the hike in prices?  Well, if you're a fan of places like Chipotle and Five Guys, that's why.A burger and fries at a Five Guys will cost you around . Casual restaurants like Five Guys have become so popular that fast-food joints like Burger King and McDonald’s realize consumers are willing to pay a few bucks more for food.  Additionally, fast-food workers are finally getting paid a bit more, so in order to offset that cost, chains are charging more for food.But despite the rise in prices, the chains still offer a quick meal and serve up great deals throughout the year. 1077

Happening now: a new eruption of Kīlauea inside Halema?uma?uSee live webcams inside Halema?uma?u, courtesy of USGS Hawaiian Volcano Observatory: https://t.co/Yf1Kc3AeJ9 pic.twitter.com/bsNmt3ZTUg— Hawaii Volcanoes NPS (@Volcanoes_NPS) December 21, 2020 266