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LOS ANGELES, April 2 (Xinhua) -- People taking antidepressants may be more likely to develop thicker arteries which may raise the risk of heart disease and stroke, a new study suggests.Depression can heighten the risk for heart disease, but the effect of antidepressant use is separate and independent from depression itself, according to the study make public by the American Association for the Advancement of Science (AAAS) on Saturday.The data suggest that antidepressants may combine with depression for a negative effect on blood vessels, said study first author Amit Shah, MD, a cardiology fellow at Emory University School of Medicine.Study findings will be presented on April 5 at the American College of Cardiology meeting in New Orleans, according to the AAAS.The study included 513 middle-aged male twins who both served in the U.S. military during the Vietnam War. Twins are genetically the same but may be different when it comes to other risk factors such as diet, smoking and exercise, so studying them is a good way to distill out the effects of genetics.Researchers measured carotid intima-media thickness - the thickness of the lining of the main arteries in the neck -- by ultrasound. Among the 59 pairs of twins where only one brother took antidepressants, the one taking the drugs tended to have higher carotid intima-media thickness (IMT), even when standard heart disease risk factors were taken into account.The effect was seen both in twins with or without a previous heart attack or stroke. A higher level of depressive symptoms was associated with higher IMT only in those taking antidepressants."One of the strongest and best-studied factors that thickens someone's arteries is age, and that happens at around 10 microns per year," Shah said. "In our study, users of antidepressants see an average 40 micron increase in IMT, so their carotid arteries are in effect four years older."Antidepressants' effects on blood vessels may come from changes in serotonin, a chemical that helps some brain cells communicate but also functions outside the brain, Shah said."I think we have to keep an open mind about the effects of antidepressants on neurochemicals like serotonin in places outside the brain, such as the vasculature. The body often compensates over time for drugs' immediate effects," Shah said. " Antidepressants have a clinical benefit that has been established, so nobody taking these medications should stop based only on these results. This isn 't the kind of study where we can know cause and effect, let alone mechanism, and we need to see whether this holds up in other population groups."
CARACAS, March 30 (Xinhua) -- The number of confirmed cases of the A/H1N1 influenza in Venezuela has risen to 482 this year, Health Minister Eugenia Sader said on Wednesday.According to the latest report, the state of Merida in southeastern Venezuela has 189 A/H1N1 influenza cases, the biggest number ever reported, which was followed by the Capital District of Caracas with 112 cases. The other 181 cases were confirmed in 17 of 24 Venezuelan states.The first case for this year was reported in Merida earlier this month.Sader said that the Venezuelan government was trying to prevent the spread of the disease. Some 3 million people have been vaccinated against the virus.Three patients infected with the A/H1N1 influenza virus have died in the country this year, according to Sader.The A/H1N1 influenza can cause deadly pneumonia if it is not treated early.
SAN FRANCISCO, March 21 (Xinhua) -- Microsoft on Monday sued Barnes & Noble, claiming patent infringement by the largest book retailer in the United States.Microsoft said it filed legal actions on Monday in both the U.S. International Trade Commission and the U.S. District Court of the Western District of Washington against Barnes & Noble, as well as Foxconn and Inventec, two manufacturers of Barnes & Noble's devices.According to Microsoft, the actions focus on the patent infringement by Barnes & Noble's Nook e-reader and tablet, both of which run Google's Android operating system.The patents at issue cover a range of functionality embodied in Android devices that are essential to the user experience, including natural ways of interacting with devices by tabbing through various screens to find the information they need, surfing the Web more quickly and interacting with documents and e-books, Microsoft said in a press release."The Android platform infringes a number of Microsoft's patents, and companies manufacturing and shipping Android devices must respect our intellectual property rights," Horacio Gutierrez, Microsoft's corporate vice president and deputy general counsel, was quoted by the press release as saying.Writing in a separate company blog post, Gutierrez said that the latest actions bring to 25 the total number of Microsoft patents in litigation for infringement by Android smartphones, tablets and other devices.He noted that Microsoft has established a licensing program to address Android's ongoing infringement, and leading Android smartphone manufacturer HTC has taken a license under this program.Amazon.com also signed a patent license with Microsoft last year covering its Kindle e-reader, he added."Unfortunately, after more than a year of discussions, Barnes & Noble, Foxconn and Inventec have so far been unwilling to sign a license, and therefore, we have no other choice but to bring legal action to defend our innovations," Gutierrez said in the blog post.
PYONGYANG, Feb. 14 (Xinhua) -- Kim Yong Nam, president of the Presidium of the Supreme People's Assembly of the Democratic People's Republic of Korea (DPRK), met Chinese Minister of Public Security Meng Jianzhu here on Monday.Kim said it was the consistent stand of the Worker's Party of Korea (WPK) and the government and the firm will of the people to develop the traditional DPRK-China friendship generation after generation.The DPRK is sincerely happy to see the great achievement China has made and wish that the Chinese people make even more progress, Kim said.Meng, also a State Councilor, said the traditional friendship between the two neighboring countries has strengthened through the ages. He expressed his expectations of inheriting the friendship, deepening communications and cooperation in various areas and promoting the China-DPRK friendship.Ri Yong Ho, Presidium of Political Bureau of Central Committee of WPK and chief of the Korean People's Army General Staff, also met Meng on the same day.Ju Sang Song, a member of the Political Bureau of Central Committee of the WPK and Minister of People's Security, met Meng on Sunday. The two achieved consensus on making more efforts to develop cooperation and communications on public security to make active contributions to the traditional China-DPRK friendship. An agreement on cooperation between the the two security ministries was signed after the meeting.Meng arrived at Pyongyang on Sunday at the invitation of Ju Sang Song.
BEIJING, March 17 (Xinhuanet) -- A new study has shown that gene therapy can reduce symptoms in patients with Parkinson's, media reports said Thursday.The study, published in the journal Lancet Neurology, is the first to show positive results in a test of gene therapy against a sham operation in 45 U.S. Parkinson's patients.The treated group showed a 23.1 percent improvement on a scale of Parkinson's symptoms six months after treatment, compared to a 12.7 percent improvement for patients who received sham surgery, according to the published research."Gene therapy is no longer just a theory," said Michael Kaplitt, a neurosurgeon at New York-Presbyterian Hospital and Weill Cornell Medical Center, and one of the study authors. "We are getting much closer to a reality where this treatment can be offered to patients."In patients with Parkinson's disease, their brains get overactive after losing the normal supply of a chemical called GABA. The new treatment, gene therapy, works by inserting billions of copies of a gene into patients' brains that helps them produce more GABA.Kaplitt said the results might spur similar treatments for other brain disorders like Alzheimer's, epilepsy and depression.