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WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday revoked its approval of Avastin for treating the breast cancer after concluding that the drug has not been shown to be safe and effective for that use.Avastin will still remain on the market as an approved treatment for certain types of colon, lung, kidney and brain cancer."After reviewing the available studies it is clear that women who take Avastin for metastatic breast cancer risk potentially life-threatening side effects without proof that the use of Avastin will provide a benefit, in terms of delay in tumor growth, that would justify those risks," FDA Commissioner Margaret Hamburg said in a statement. "Nor is there evidence that use of Avastin will either help them live longer or improve their quality of life. "Avastin's risks include severe high blood pressure; bleeding and hemorrhaging; heart attack or heart failure; and the development of perforations in different parts of the body such as the nose, stomach, and intestines.Avastin was approved for metastatic breast cancer in February 2008 under the FDA's accelerated approval program, which allows a drug to be approved based on data that are not sufficiently complete to permit full approval. After the approval, the drug's sponsor, Genentech, completed two additional clinical trials and submitted the data from those studies to the FDA. These data showed only a small effect on tumor growth without evidence that patients lived any longer or had a better quality of life compared to taking standard chemotherapy alone -- not enough to outweigh the risk of taking the drug.FDA's Center for Drug Evaluation and Research, which is responsible for the approval of this drug, ultimately concluded that the results of these additional studies did not justify continued approval and notified Genentech it was proposing to withdraw approval of the indication.Genentech did not agree with the Center's evaluation of the data and, following the procedures set out in FDA regulations, requested a hearing on the Center's withdrawal proposal, with a decision to be made by the Commissioner. That two-day hearing, which took place June 28-29, included recommendations from the FDA 's Oncologic Drugs Advisory Committee, voting 6-0 in favor of withdrawing approval of Avastin's breast cancer indication.
BEIJING, Jan. 8 (Xinhua) -- China started the Spring Festival peak travel season Sunday, with tens of millions of passengers, mainly migrant workers and college students, on the move in the world's largest seasonal migration.The Spring Festival, or Chinese Lunar New Year, fall on Jan. 23 this year. It is the most important traditional Chinese festival for family reunions.A total of 3.16 billion passenger trips are expected during the 40-day peak travel season, or Chunyun (Spring transportation) in Chinese, up 9.1 percent from a year earlier, according to the National Development and Reform Commission.

WASHINGTON, Nov. 24 (Xinhua) -- A new study suggests that the rate of global warming from doubling of atmospheric carbon dioxide may be less than the most dire estimates of some previous studies.Authors of the study, which was funded by the National Science Foundation and published online on Thursday in the journal Science, say that global warming is real and that increases in atmospheric CO2 will have multiple serious impacts. However, the most Draconian projections of temperature increases from the doubling of CO2 are unlikely."Many previous climate sensitivity studies have looked at the past only from 1850 through today, and not fully integrated paleoclimate date, especially on a global scale," said Andreas Schmittner, an Oregon State University researcher and lead author on the Science article. "When you reconstruct sea and land surface temperatures from the peak of the last Ice Age 21,000 years ago -- which is referred to as the Last Glacial Maximum -- and compare it with climate model simulations of that period, you get a much different picture.""If these paleoclimatic constraints apply to the future, as predicted by our model, the results imply less probability of extreme climatic change than previously thought," Schmittner added.Scientists have struggled for years trying to quantify "climate sensitivity" -- which is how the Earth will respond to projected increases of atmospheric carbon dioxide. The 2007 IPCC report estimated that the air near the surface of the Earth would warm on average by two to 4.5 degrees (Celsius) with a doubling of atmospheric CO2 from preindustrial standards. The mean, or " expected value" increase in the IPCC estimates was 3.0 degrees; most climate model studies use the doubling of CO2 as a basic index.The researchers based their study on ice age land and ocean surface temperature obtained by examining ices cores, bore holes, seafloor sediments and other factors. When they first looked at the paleoclimatic data, the researchers only found very small differences in ocean temperatures then compared to now."Our study implies that we still have time to prevent that from happening, if we make a concerted effort to change course soon," said Schmittner.
BEIJING, Dec. 2 (Xinhua) -- China cannot use its 3.2 trillion U.S. dollars in foreign exchange reserves to rescue other countries, a senior diplomat said on Friday."The argument that China should rescue Europe does not stand, as reserves are not managed that way," Vice Foreign Minister Fu Ying said at the Lanting forum, a gathering of Chinese officials, scholars and social groups held by the Ministry of Foreign Affairs to discuss international issues and foreign policy."China is not absent from international efforts to rescue Europe; it has been a positive and healthy participant," Fu said.Since the outbreak of the European financial crisis, China has dispatched more than 30 procurement delegations to Europe, helping to boost imports from the continent, Fu said.Fu added that there are many misunderstandings about the use of China's foreign reserves. "Foreign reserves are not domestic income or money that can be disposed of by the premier or finance minister," she said."Foreign reserves are akin to savings, and their liquidity should be ensured," Fu said."Foreign reserves are not revenue and cannot be relocated randomly. Under this circumstance, China should take the prospect of yields into consideration if it invests its foreign reserves," said Tian Dewen, an analyst at the Institute of European Studies at the Chinese Academy of Social Sciences.However, the outlook for the economic situation in the eurozone is currently uncertain, Tian said.Fu said China learned a lesson about the importance of foreign reserves during the Asian financial crisis of the late 1990s. ' "Reserves cannot be used domestically to alleviate poverty or taken abroad for development support," she said.She said that the way in which foreign reserves are managed should be in line with the principles of "safety, liquidity and proper profitability.""China's purchases of European bonds, International Monetary Fund bonds and U.S. bonds are also based on those principles," Fu said.Fu also said that China has no intention to gain profit by leveraging financial instruments."China will make efforts to overcome the crisis with Europe and the international community in the future," Fu said."As for the current turbulence in European markets, an authoritative voice is necessary in restoring market confidence. However, voices are diversified in Europe due to its political framework," said Chen Xin, an analyst at the Institute of European Studies at the Chinese Academy of Social Sciences.Fu also reviewed achievements made in trade and investment cooperation between the two sides."It is normal for Europe to strengthen its economic cooperation with China in the process of conquering its difficulties, although it is not proper to add negative political implications," Fu said.She urged Europe not to politicize China's foreign investments."Successful investment should be reciprocal. We hope our economic activities are not interpreted from a political prospective and are not imbued with political interests. We should follow market economy principles," Fu saidFu also took time to single out media reports about the crisis that she believes have been overtly political."Many European countries have shown their understanding and support for us, but there have also been some negative reports," Fu said."We should treat each other with a moderate and impartial mentality. That will make bilateral relations easier to handle," Fu said.She cited an investment bid by a Chinese company in Iceland that was turned down by the country's government.Zhongkun, a private Chinese real estate company founded in 1995, planned to buy 300 square km of land in Iceland to build a high-end resort with a total investment of 200 million U.S. dollars.However, Iceland's Interior Ministry rejected the bid, citing the size of the area of land involved and the fact that there is no precedent in Iceland for foreign countries to purchase large tracts of land.
BEIJING, Jan. 15 (Xinhua) -- The winning of Ma Ying-jeou and Kuomintang (KMT) in Saturday's elections may open new chances for the peaceful development of cross-Strait relations.The results of the elections have indicated that the peaceful development of the cross-Strait relations is a correct path and has been widely recognized by the Taiwan people.Any persons and any political parties of Taiwan should follow this trend, so that they could earn recognition and support.Moreover, the victory of Ma and the KMT may represent a new opportunity for the development of the cross-Strait relations.With joint efforts of the two sides to fortify and enhance the existing mutual trust, there will be a even brighter prospect and further progresses in the cross-Strait talks, exchanges and cooperation.However, the two sides should be wary that the situation in the island is still complicated and the "Taiwan independence" stance will continue to haunt the cross-Strait relations development.There are still some long-term disputes and divergences existing between the two sides that await resolving.This year's elections were carried out under a background in which the cross-Strait relations have been significantly improved. The positive effects of the peaceful development of the cross-Strait relations have fully emerged.Over the past four years, the two sides of the Taiwan Strait have established a political mutual trust based on opposition to the "Taiwan independence" stance and adherence to the "1992 Consensus."The two sides resumed regular talks between the mainland's Association for Relations Across the Taiwan Straits (ARATS) and the Taiwan-based Straits Exchange Foundation (SEF) in 2008.The opening of "three direct links" of cross-Strait mail, trade, air and shipping services, has also pushed forward the cross-Strait economic cooperation into a brand-new stage.These achievements have brought about real benefits to the people on both sides of the Strait, especially the people in Taiwan.The cross-Strait economic cooperation has also helped the island's economy to buoy up from blows of the global financial crisis.The peaceful development of the cross-Strait ties have won a widespread support among the Taiwan people and it is also appreciated by the international community.During the election campaigns, whether to stick to the 1992 Consensus became a major field of cross fires among candidates. Ma had stood out and gained positive momentum with his cross-Strait policies.Numbers of Taiwanese notables, business tycoons as well as the small and medium-sized enterprise owners and the grassroots people have also expressed their stance for the "1992 Consensus" and their aspiration for further peaceful development of the cross-Strait ties.Under the public's pressure, the Democratic Progressive Party and its candidate Tsai Ing-wen have to lower their voices for "Taiwan independence."But their denial of the "1992 Consensus" and the stance of "one country on each side" could not abate the people's doubts and worries and finally led to their failure in the elections.Judged from the election, peaceful development of cross-Strait relations have developed from a concept to reality, benefitting people from different backgrounds and recognized by the public.
来源:资阳报