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LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.

BERLIN, Aug. 28 (Xinhua) -- Mercedes-Benz, the world leading luxury car producer, celebrates the 125th anniversary of its invention of automobile with what it claimed the largest gathering ever, at the former Tempelhof airport in Berlin on the weekend.The Mercedes-Benz Club and Mercedes-Benz enthusiasts greet visitors with some 1,800 well-assorted Mercedes-Benz-branded vehicles, ranging from vintage and classic passenger cars to a variety of historic commercial vehicles, on a vast open areas of 250,000 square metres of the abandoned Tempelhof airport, which was closed in 2008.It took Mr. Lauritzen and his wife two days' drive of their cherised wecker of Mercedes-Benz Cabriolet B. 320.W 142.-3,4l to reach here for taking part in the pageant."It is a long journey, but we are happy to be here to see more class cars and more friends with same interests," Mrs Lauritzen said.Owners take the opportunity to present their lovingly cared-for vehicles, which include a number of truly rare items of automotive history, to the Berlin public.The couple of Mr. Kerner drove their red Mercedes-Benz 170Dba, a made-in-1952 model with a range of special and unique designs which are very rarely seen now, over journey of 155 km from Bitterfeld to join in the gala."I'm fond of driving my classic car of Benz," said Mrs Kerner, despite it can run maximally at a speed of 50 to 80 km per hour, "but I truly enjoy the diesel engine sounds and the historic feeling it evokes."The legendary Silver Arrows, dating from the 1930s and 1950s, are also presented from the Mercedes-Benz Classic collection for demonstration drives."The brilliant history of the Silver Arrows will be brought to life with a demonstration of their impressive engine sound and incredible driving dynamics," said Michael Bock, head of Mercedes-Benz Classic and Director of Mercedes-Benz Museum GmbH."It is not often that these racing cars are driven in public, so this will be a true highlight of the program of events in Tempelhof."During the grand show, visitors are also accessible to first-hand experiences of the latest technologies applicable in the future for in passenger cars, commercial vehicles and racing cars."Some 125 years ago, Carl Benz submitted his patent application for the Benz Patent Motor Car to the Patent Office in Berlin", the organizer appealed to the visitors, saying now Mercedes-Benz is returning to Berlin to celebrate together with Berliners.

BEIJING, Sept. 6 (Xinhuanet) -- NASA will launch on Thursday twin lunar orbiters built to map the gravity of Earth's moon in unprecedented detail, media reported Tuesday.The twin lunar probes, Graili-A and Graili-B, will blast off from Florida's Cape Canaveral Air Force Station at 8:37 a.m. EDT and at 9:16 a.m. EDT respectively Thursday, according to NASA.The Grail twins will travel three to four months to get to the moon under a slower but more economical plan.Artist concept of GRAIL mission. Grail will fly twin spacecraft in tandem orbits around the moon for several months to measure its gravity field in unprecedented detail.The two spacecrafts will reach the moon around New Year's Day when they will begin to probe the moon's composition from the crust to the core, according to NASA.The data collected by the probes will be used to better understand the moon's evolution and formation, NASA scientists said.Researchers will also use the twin probes to pinpoint the best landing sites for future explorations.The mission, from start to finish, costs 496 million U.S. dollars. The two Grail probes will crash into the moon after its mission.

CANBERRA, Aug. 17 (Xinhua) -- Australian scientist on Wednesday said his international research team has discovered the trick on how butterfly learn to change its wing pattern to avoid being eaten by birds.The Amazonian butterfly, Heliconius numata, has learnt to carry out a single genetic switch to alter its wing pattern so it appears to be another bad-tasting butterfly that birds will avoid.Dr. Siu Fai (Ronald) Lee from the Department of Genetics and Bio21 Institute at Australia's University of Melbourne was part of the international research team, which was led by scientists at Centre National de la Recherche Scientifique (CNRS) and the University of Exeter in United Kingdom.Dr. Lee said the historical mystery had puzzled researchers for decades."Charles Darwin was puzzled by how butterflies evolved such similar patterns of warning coloration," Dr. Siu Fai (Ronald) Lee from the Department of Genetics and Bio21 Institute at the University of Melbourne told Western Australia Today."We have now solved this mystery, identifying the region of chromosome responsible for changing wing pattern."He said the research team identified a genetic switch known as a supergene, which allowed the butterfly to morph into several different forms, allowing one species to mimic another."It is amazing that by changing just one small region of the chromosomes, the butterfly is able to fool its predators by mimicking a range of different butterflies that taste bad," he said."The butterflies rearrange this supergene DNA like a small pack of cards, and the result is new wing patterns. It means that butterflies look completely different but have the same DNA."There are other butterflies doing similar tricks, but this is the most elegant one."I was just fascinated by how elegant they were."He said the discovery proves that small chromosomal changes can preserve successful gene combinations, and thus help a species to adapt.The findings of the study are published on August 14 in the international journal Nature.

WARSAW, June 2 (Xinhua) -- A possible second E. coli infection patient has been hospitalized in Szczecin, northwestern Poland, Health Minister Ewa Kopacz said Thursday.The man, who recently returned to Poland from Germany, has been diagnosed with exudative diarrhea and is currently being tested for E. coli bacteria.Poland's first E. coli case, a 29-year-old woman permanently residing in Germany and diagnosed with the bacteria over a week ago, is currently in the same hospital.Kopacz said sanitary teams were running E. coli checks countrywide, especially on marketplaces and in warehouses.The E. coli epidemic originated in Germany, where it has taken 17 lives. One death has so far occurred in Sweden, bringing the total death toll to 18.