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SAN DIEGO (KGTV) — It's a new season with new threads for the San Diego Padres.The Padres unveiled new home and away sets of uniforms sporting the team's classic brown colors during a fashion show-style event at Petco Park Saturday.Third baseman Manny Machado, first baseman Eric Hosmer, and shortstop Fernando Tatis Jr. were on hand to model the new look the Friars take into 2020. Two styles of the new uniforms featured a return to pinstripes, one on a white base reading "Padres" and the other on dark gray reading "San Diego." The third uniform was brown with gold "San Diego" across the chest and dark gray pants. 627

SAN DIEGO (KGTV) -- Millions of dollars have been raised and spent in the race to fill the seat for the 50th Congressional District.According to a recently released 10News/Union-Tribune scientific poll, Democrat Ammar Campa-Najjar and Republican Darrell Issa have emerged as the favorites to represent East County's 50th Congressional District.Federal Election Commission (FEC) records show Issa is currently leading in the money game as well. 451

SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) — Kids, parents, and youth sports leaders held a protest in front of the San Diego County Administration Building on Saturday to voice their concerns over the state’s regulations regarding games and competitions.Currently, under California coronavirus restrictions, youth sports can practice, as long as six feet of social distancing can be maintained, but they can't play games. People who gathered Saturday said the lack of games is taking a toll on the youth.“Thank you for honoring our safety but I think our mental health is important as well and for that to be good and top-notch, we need to be allowed to play our sports and escape from life,” said 7th grader Zoey Hagan, who stood with other girls in her soccer club.Bob Turner is both Executive Director of Presidio Soccer League and President of the Southern California Youth Soccer Association and said the athletes should be able to play games. He said they have created safety plans, including spacing out the times of games and shortening games to avoid crowds, only allowing one parent for each athlete, and also requiring masks of all referees, parents, and substitute players. Turner said they’ve sent countless letters and filled-out petitions to the state, but have not gotten a response. A spokesperson for San Diego County said the county has also been asked about plans for youth sports. They also asked the state and have not heard about what’s next.“This is small potatoes to them compared to a lot of the other things opening but it is our youth and what’s more important than our kids. We’re destroying these kids with what’s happening through the schools and now we’re taking this away. This is the only outlet some of these kids have,” said Turner.At Saturday’s protest, speakers took turns sharing their personal experiences. One parent questioned why other businesses can operate, but these athletes can’t play games.“It is infuriating to me that we’ll open up beaches, we’ll open up Home Depot, we’ll open up restaurants. These people can make their money. We can take care of the adults and make sure they’re doing well, but our kids are sequestered?” he said, addressing the crowd.After a handful of speakers comprised of parents and athletes took to the podium, a group of young athletes held a 'what about us' banner and marched around the admin building while chanting "let us play." 2394

SAN DIEGO (KGTV) — King tides are expected to hit San Diego County's coastline starting this weekend.The high tide event is forecasted to begin Sunday, Nov. 15, and last through Monday, Nov. 16, according to the California King Tides Project. Another round of king tides is also expected next month from Dec. 13 through Dec. 15.High tide is set to steadily rise through the weekend, with Friday's high tide reaching 6.9 feet ahead of Saturday's 7.3-foot high tide. Sunday and Monday will see high tide reach 7.5 feet, before gradually decreasing through the remainder of the week, according to Tide Forecast.FORECAST: Latest 10News weather forecast for San Diego County"King tide" is the term used to refer to the natural occurrence of higher than normal tide caused by the alignment of the gravitational pull between the sun, moon, and Earth. While the tide event isn't an everyday occurrence, it is a natural one.According to the California King Tides Project, king tides are generally the highest tides of the year. The group says that understanding king tides help plan for higher sea levels in the future, though the event is not caused by a rise in sea levels."King Tides are the highest high tides of the year, about a foot or two higher than average tides, which corresponds to the one to two foot rise in sea level expected during the next few decades. When you observe the King Tides, imagine seeing these tides (and the associated flooded streets, beaches, and wetlands) almost daily," according to the group.While the event has the ability to produce lively imagery of tide crashing onshore, beach-goers are warned to be careful when near the shoreline, especially if they're near an area prone to erosion. Coastal flooding, affecting businesses and residences, can also occur during these high tide events. 1827