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Three students who gave their lives when a gunman opened fire inside a Florida high school will be awarded Medal's of Heroism by the U.S. Army, a spokesperson told Scripps station WFTS in Tampa.According to the U.S. Army, "The Medal of Heroism is a U.S. military decoration awarded by the Department of the Army to a JROTC Cadet who performs an act of heroism. The achievement must be an accomplishment so exceptional and outstanding that it clearly sets the individual apart from fellow students or from other persons in similar circumstances. The performance must have involved the acceptance of danger and extraordinary responsibilities, exemplifying praiseworthy fortitude and courage."Related:17 dead in south Florida school shooting, 19-year-old suspect held without bondFlorida school shooting 'hero' JROTC cadet should receive military burial, classmates sayCoach dies after heroically shielding students from gunfire in Florida school shooting 965

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

TOWN OF DOVER, Wis. -- Authorities believe a woman who escaped from the Robert E. Ellsworth Correctional Center Thursday broke into a nearby home and stole a pickup truck. The escapee was identified as 36-year-old Christine Abel.The Racine County Sheriff's Office was alerted to a break-in at a home 2 miles away from the prison at around 9:30 p.m. Someone stole a 2007 black GM Sierra pickup with a registration plate of MZ1698. An hour later, the prison reported Abel missing during a head count.  522

They’ve been fighting in Wisconsin and Pennsylvania over the cutoff date for counting mailed ballots, and in North Carolina over witness requirements. Ohio is grappling with drop boxes for ballots as Texas faces a court challenge over extra days of early voting.Measuring the anxiety over the November election is as simple as tallying the hundreds of voting-related lawsuits filed across the country in recent months. The cases concern the fundamentals of the American voting process, including how ballots are cast and counted, during an election made unique by the coronavirus pandemic and by a president who refuses to commit to accepting the results.The lawsuits are all the more important because President Donald Trump has raised the prospect that the election may wind up before a Supreme Court with a decidedly Republican tilt if his latest nominee is confirmed.“This is a president who has expressed his opposition to access to mail ballots and has also seemed to almost foreshadow the inevitability that this election will be one decided by the courts,” said Kristen Clarke, executive director of the National Lawyers Committee for Civil Rights Under Law.That opposition was on display Tuesday during the first presidential debate when Trump launched into an extended argument against mail voting, claiming without evidence that it is ripe for fraud and suggesting mail ballots may be “manipulated.”“This is going to be a fraud like you’ve never seen,” the president said of the massive shift to mail voting prompted by the pandemic.The lawsuits are a likely precursor for what will come afterward. Republicans say they have retained outside law firms, along with thousands of volunteer lawyers at the ready. Democrats have announced a legal war room of heavyweights, including a pair of former solicitors general.The race is already regarded as the most litigated in American history, due in large part to the massive expansion of mail and absentee voting. Loyola Law School professor Justin Levitt, a former Justice Department elections official, has tallied some 260 lawsuits arising from the coronavirus. The Republication National Committee says it’s involved in more than 40 lawsuits, and a website operated by a chief Democrat lawyer lists active cases worth watching in about 15 states.Democrats are focusing their efforts on multiple core areas — securing free postage for mail ballots, reforming signature-match laws, allowing ballot collection by third-parties like community organizations and ensuring that ballots postmarked by Election Day can count. Republicans warn that those same requests open the door to voter fraud and confusion and are countering efforts to relax rules on how voters cast ballots this November.“We’re trying to prevent chaos in the process,” RNC chief counsel Justin Riemer said in an interview. “Nothing creates more chaos than rewriting a bunch of rules at the last minute.”But there have been no broad-based, sweeping examples of voter fraud during past presidential elections, including in 2016, when Trump claimed the contest would be rigged and Russians sought to meddle in the outcome.Some of the disputes are unfolding in states not traditionally thought of as election battlegrounds, such as Montana, where there is a highly competitive U.S. Senate race on the ballot. A judge Wednesday rejected an effort by Trump’s reelection campaign and Republican groups to block counties from holding the general election mostly by mail.But most of the closely watched cases are in states perceived as up-for-grabs in 2020 and probably crucial to the race.That includes Ohio, where a coalition of voting groups and Democrats have sued to force an expansion of ballot drop boxes from more than just one per county. Separately on Monday, a federal judge rejected changes to the state’s signature-matching requirement for ballots and ballot applications, handing a win to the state’s Republican election chief who has been engulfed with litigation this election season.In Arizona, a judge’s ruling that voters who forget to sign their early ballots have up to five days after the election to fix the problem is now on appeal before the 9th U.S. Circuit Court of Appeals.A federal appeals court on Tuesday upheld a six-day extension for counting absentee ballots in Wisconsin as long as they are postmarked by Election Day. The ruling gave Democrats in the state at least a temporary victory in a case that could nonetheless by appealed to the U.S. Supreme Court. In neighboring Michigan, the GOP is suing to try to overturn a decision that lets the state count absentee ballots up to 14 days after the election.In battleground North Carolina, where voters are already struggling with rules requiring witness signatures on absentee ballots, the RNC and Trump’s campaign committee have sued over new election guidance that will permit ballots with incomplete witness information to be fixed without the voter having to fill out a new blank ballot.In Iowa, the Trump campaign and Republican groups have won a series of sweeping legal victories in their attempts to limit absentee voting, with judges throwing out tens of thousands of absentee ballot applications in three counties. This week, another judge upheld a new Republican-backed law that will make it harder for counties to process absentee ballot applications.Pennsylvania has been a particular hive of activity.Republican lawmakers asked the U.S. Supreme Court on Monday to put a hold on a ruling by the state’s highest court that extends the deadline for receiving and counting mailed-in ballots. Republicans also object to a portion of the state court’s ruling that orders counties to count ballots that arrive during the three-day extension period even if they lack a postmark or legible postmark.Meanwhile in federal court, Republicans are suing to, among other things, outlaw drop boxes or other sites used to collect mail-in ballots.The Supreme Court itself has already been asked to get involved in several cases, as it did in April, when conservative justices blocked Democratic efforts to extend absentee voting in Wisconsin during the primary.There is, of course, precedent for an election that ends in the courts. In 2000, the Supreme Court settled a recount dispute in Florida, effectively handing the election to Republican George W. Bush.Barry Richard, a Florida lawyer who represented Bush during that litigation, said there’s no guarantee the Supreme Court will want to get involved again, or that any lawsuit over the election will present a compelling issue for the bench to address.One significant difference between then and now, he said, is that neither candidate raised the prospect of not accepting the results.“There was never any question, in 2000, about the essential integrity of the system. Neither candidate challenged it,” Richard said. “Nobody even talked about whether or not the losing candidate would accept the results of the election. That was just assumed.”_____Follow Eric Tucker on Twitter at http://www.twitter.com/etuckerAP 7075

Today our office issued a letter to Kanye West informing him of the insufficiency of his independent candidate nomination petition for President. The petition was determined to have 6,557 valid signatures of the required 10,000. pic.twitter.com/vxOSk8WCD3— Missouri SOS Office (@MissouriSOS) August 25, 2020 315