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Scientists at the University of Nevada, Reno School of Medicine (UNR Med), led by its Nevada State Public Health Laboratory (NSPHL) are studying a likely case of COVID-19 reinfection.Forty-eight days after testing positive for SARS-CoV-2 in April 2020 and after testing negative consecutively twice, a Washoe County, Nevada patient tested positive again, in June.The patient had tested negative on two separate occasions in the interim. The genomes of the patient’s virus samples were sequenced in April and June, displaying significant genetic discordance between the two cases, implying the patient was infected twice.“We examined the genomic material of the viruses and samples to investigate this, says NSPHL Director Mark Pandori. “It is just one finding, but it shows that a person can possibly become infected with SARS-CoV-2 a second time.”To solidify confidence in the case, Pandori and the research team partnered with the Washoe County Sheriff’s Office Biology Unit to conduct identity testing on the specimens and lab samples evaluated in the study to verify the specimens were from the same person.Embedded in the genomic material of SARS-CoV-2 is a detailed code that Pandori says may provide insight to a better understanding of this virus.“A virus has a biological genome like all living things. Since March, the NSPHL has analyzed the genomic RNA of approximately 200 positive COVID-19 samples from Nevadans who have tested positive for COVID-19,” said Pandori. “The power of genomic information could turn the tables in the fight against the coronavirus.” The information is shared to a world-wide database known as “GISAID”,” alongside the work of thousands of researchers.According to Pandori and the NSPHL-led research team, reinfection cases are a potential warning sign that it is possible to catch COVID-19 more than once, and with unpredictable severity.“If reinfection is possible on such a short timeline, there may be implications for the efficacy of vaccines developed to fight the disease. It may also have implications for herd immunity,” says Pandori. “It is important to note, that this is a singular finding. It does not provide any information to us with regard to the generalizability of this phenomenon.”Herd immunity depends on the theory that after natural infection, our immune systems will collectively protect us as a community from reinfection and further spread. There are currently many more unknowns than knowns about immune responses to COVID-19. “After one recover from COVID-19, we still do not know how much immunity is built up, how long it may last, or how well antibodies play a role in protection against reinfection,” says Pandori.”While research and scientific advancements continue to build, Pandori says the hard work of fighting this pandemic together will continue through the use of facial coverings, hand-washing, social distancing, as well as wide-scale testing, contact tracing, and isolation of new cases.“This is a novel disease. We still have a steep learning curve ahead and lots of work to do, especially as inconvenient truths arise,” says Pandori.The NSPHL team are publishing their COVID-19 reinfection findings. Their report is publicly accessible on the SSRN preprint server, at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3681489. This story was first reported by KTNV in Las Vegas, Nevada. 3384

SAN FRANCISCO (AP) — Two girls who were lost in a dense Northern California forest for nearly two days say they survived frigid nights by huddling under a tree branch and a huckleberry bush and by thinking "happy thoughts."Leia Carrico, 8, and her 5-year-old sister Caroline, said in an interview Monday they went on a hike last Friday past a marker that their parents told them not to pass because they wanted an adventure but lost their way home."I just wanted a little more adventure, I said to go a little farther," Caroline said.Leia said her sister cried the entire first night and she told her to think happy thoughts as they huddled under a tree branch close to the ground."I thought of going to the park with mommy and daddy. I thought of going to the ocean. I thought of everything I remembered, but it didn't work," Caroline said.Leia kept watch both nights and thought about the good memories from a family vacation to Monterey, California, she said.She said she also remembered what she learned from watching movies of people surviving in the wilderness, going camping every summer and the training with their local 4-H club. She also thought of her father's advice to stay put if she ever got lost."I knew dad would find us eventually," she said.Two volunteer firefighters who joined hundreds looking for the sisters found them Sunday in a wooded area about 1? miles (2.3 kilometers) from their home in the small community of Benbow, about 200 miles (320 kilometers) northwest of Sacramento.Delbert Chumley, a Piercy volunteer firefighter, said he and fellow volunteer firefighter, Abram Hill, found the girls after calling out their names during a long hike through rugged terrain."I thought we heard someone say 'dad' and so then we called out again and they said yes we are right here," Chumley said.The girls' mother, Misty Carrico, said she is trying not to punish them."They might have wandered off but they stuck together and they pulled themselves through," she said. "They saved each other."For now, the girls are not allowed to go far away from their house until they have a GPS trackers, which their mother has already ordered. 2160

SAN MARCOS, Calif. (KGTV) - Some people in San Marcos think the city is growing too big, too fast, and they're asking the City Council to change a decision on zoning to slow development. 194

SAN YSIDRO, Calif. (KGTV) -- Authorities are investigating a shooting involving U.S. Customs and Border Protection near the San Ysidro Port of Entry Monday night. The San Diego Police Department told 10News the suspect is a 23-year-old man in a white pickup truck who was trying to drive into the United States from Mexico.Police say he had been directed to a secondary screening area but failed to stop for an inspection and began firing at border agents. The man attempted to drive away, but authorities shot back. SDPD said at least seven CBP officers fired their weapons, killing the driver.According to a witness who was driving to the border from National City, police could be heard telling someone to pull over. The witness added that a police helicopter could also be seen in the area. San Diego Police say they're helping with the shooting investigation, which originally involved Border Patrol and CBP. Marco Sotomayor, Secretary of Public Security in Tijuana, tweeted that CBP closed all lanes of the port during the incident, but quickly reopened them. 1075

SAN TAN VALLEY, Ariz. — Authorities are asking people to be on alert after a man in a white SUV attempted to lure a 10-year-old girl in San Tan Valley, Arizona on Wednesday. According to the Pinal County Sheriff's Office, shortly before 4 p.m., a 10-year-old girl was walking with a friend near a park in the North Pecan Creek neighborhood when a man driving a white SUV pulled up next to them.The man reportedly told the girl that her brothers were in a serious accident and that she needed to go with him. The girl then asked the man what the "code word" was, but the man did not know and drove off."Kudos to the parents of this child for having a code word and talking about to their children about stranger danger," said Sheriff Mark Lamb. "We hope by putting this out, it will encourage parents to have that conversation and create a plan with their children, so they know what to do if they are in that situation."The SUV has been reportedly seen circling the park several times a day, according to children who live in the neighborhood. “This is generally what I consider a pretty safe area, I’ve never heard of anything bad,” said Patrick McDonald, who lives nearby.“This one time, it saved my daughters life,” said Brenda James, the girl’s mother.James talked to KNXV and the media so that other parents could learn about code words as she did.“We actually just came up that few months ago. So it was something really recent from a story that I read,” James said.The man is described as being possibly in his 40s with a short beard. The man reportedly covered most of his face with his hand while talking to the girl to conceal identifying features, officials said.“I’ll definitely be going home and having a talk with my daughter and developing a code word at the very least,” said McDonald.Anyone with information or sees the suspect, you are asked to call PCSO at (520)-866-5111 with any information. 1965

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