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WASHINGTON, Oct. 3 (Xinhua) -- Researchers at St. Michael's Hospital in Canada have discovered a new function for an enzyme that may protect against organ injury and death from anemia, according to a study appearing Monday in the U.S. journal of the Proceeding of the National Academy of Sciences.Researchers found that when people have anemia, neuronal nitric oxide synthase (nNOS) -- an enzyme in nerve cells that produces nitric oxide, an important signaling molecule in the body -- increases the body's ability to respond, adapt to low oxygen levels and makes the body more efficient in delivering oxygen to tissues. They also found that levels of nNOS in the brain increased in anemic mice, and that the mice without this enzyme die earlier, and with higher hemoglobin levels."Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study.Anemia occurs when blood has a lower than normal number of red blood cells or hemoglobin -- an iron-rich protein that carries oxygen from the lungs and heart to the rest of the body. Cells need oxygen to survive and to produce energy for all bodily functions. The condition has many different causes including infection (malaria, HIV, parasites), nutritional deficiencies (iron, folate, B12), genetic mutations, pregnancy, trauma and surgical blood loss."This research will help us identify when an anemic patient is at greatest risk for injury and death when undergoing surgery," said Hare. "Research is underway to test these findings in humans."
SAN FRANCISCO, Oct. 7 (Xinhua) -- The funeral for Apple co-founder Steve Jobs, who died Wednesday at the age of 56, is taking place on Friday, U.S. media reported.The funeral is termed as a small private gathering, The Wall Street Journal quoted a person familiar with the matter as saying.The source would not disclose where or when the event was taking place, citing respect for Jobs and his family's privacy.Apple said it has no public services planned for Jobs. In an e- mail sent to Apple staff on Wednesday, Chief Executive Officer Tim Cook said "a celebration of Steve's extraordinary life" would be held soon for employees.On its website, Apple has encouraged people to send their memories and condolence to a special e-mail address.Meanwhile, online magazine deadling.com reported Friday that Sony Pictures is making a hefty deal to acquire feature rights to "Steve Jobs," the only authorized biography of the Apple co- founder which will be published on Oct. 24.

SINGAPORE, Dec. 18 (Xinhua) -- Two Chinese Navy ships called at Singapore's Changi port on Sunday on their way back to China from an escort mission in the Gulf of Aden and the waters off Somali.The destroyer Wuhan and the frigate Yulin were part of the ninth flotilla dispatched by China in July to guard commercial ships in the troubled waters against pirates.They are stopping over in Singapore for three days to replenish fuel, water and other logistic supplies, officials said.The task force will also have exchanges with the Singapore side on anti-pirate efforts, and visit Singapore's Information Fusion Center, which is aimed to promote collaboration and information sharing in maritime security.The Chinese sailors were received at the port in Changi Naval Base on Sunday morning by Colonel Tan Kai Cheong, commander of the 3rd Flotilla, Singapore Navy; Chinese Ambassador to Singapore Wei Wei and other Chinese diplomats, as well as representatives of Chinese companies and the Chinese community in Singapore.Guan Jianguo, commander of the Chinese flotilla, said the task force left the port of Zhanjiang in Guangdong province on July 2. The two Chinese naval warships made port calls in Kuwait and Oman for friendly visits before stopping over at Singapore.The Chinese flotilla escorted 280 commercial vessels, including both Chinese and foreign ships, during the five months of the escort mission in the Gulf of Aden and the waters off Somali.Sixteen of the escorted vessels were Singapore-registered.The Chinese task force and the anti-pirate flotilla dispatched by Singapore also organized exchange visits, and the commanders of the two flotillas also met for exchanges.The Chinese Navy ships will leave Singapore on Tuesday for their home country.
BEIJING, Nov. 4 (Xinhuanet) -- The amount of trans fat and other nutritional information will be marked on the labels of prepackaged food, according to the country's first national standard for food nutrition. The labeling will take effect on Jan 1, 2013. "It will help standardize the nutrition facts labeling by food producers and facilitate consumers' rights to know and choose, while improving public awareness of food nutrition," said Yang Yuexin, a senior nutritionist with the Chinese Center for Disease Control and Prevention (CDC). The new regulation by the Ministry of Health stipulates that food labels have to include the food's nutrition information, including levels of energy, protein, fat, carbohydrate and sodium. Food products without proper labels showing the nutritional information will be banned when the new rule takes effect. The new regulation also stipulates that if any hydrogenated or partially hydrogenated fat is used to produce the food, the level of trans fat will have to be highlighted on the nutrition information label. Trans fat is usually produced during food processing when liquid oils are converted into semi-solid fats that help keep food fresh longer. However, the partially hydrogenated oil contains trans fat that can substantially increase the risk of heart disease. However, Zhang Jian, a researcher with CDC's National Institute for Nutrition and Food Safety, said that compared to Western diets, the Chinese diet contains a far lower level of trans fat and there is no need to over react.
WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy to E. coli derived asparaginase and pegapargase chemotherapy drugs used to treat ALL.Acute lymphoblastic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell. White blood cells help the body fight infection and are formed in the bone marrow.Erwinaze is injected directly into the muscle three times a week and works by breaking down one of the body's protein building blocks (the amino acid, asparagine) that is present in the blood, and is necessary for the growth of all cells. Leukemia cells cannot produce this protein building block. When a patient is treated with Erwinaze the leukemia cells die. Normal human cells are able to make enough asparagine for their own needs through biosynthesis and will not be affected by treatment with Erwinaze."The approval of Erwinaze underscores the FDA's commitment to the approval of drugs for conditions with limited patient populations with unmet medical needs using novel trial endpoints," said Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research.Side effects associated with Erwinaze treatment include serious allergic reactions, inflammation of the pancreas, high blood levels of liver enzymes, blood clotting, bleeding, nausea, vomiting and high blood sugar.
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