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WASHINGTON, Jan. 19 (Xinhua) -- New research published this week in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.The study, led by investigators with the Ohio State University Comprehensive Cancer Center, shows that overexpression of two genes called MET and EGFR causes the deregulation of six microRNAs, and that this deregulation leads to gefitinib resistance.The findings support the development of agents that restore the levels of these microRNAs. It offers a new strategy for treating non-small cell lung cancer, which is responsible for about 85 percent of the 221,000 lung-cancer cases and 157,000 deaths that occur annually in the United States. It also suggests that measuring the expression levels of certain microRNAs -- those controlled by the MET gene -- might predict which lung-cancer cases are likely to be resistant to gefitinib.Epidermal growth factor receptor (EGFR) is frequently overexpressed in non-small cell lung cancer, and this leads to uncontrolled cell proliferation. Gefitinib selectively inhibits EGFR activation and triggers cancer cells to self-destruct by apoptosis. However, non-small cell lung cancer cells inevitably develop resistance to the drug. The study reveals how this resistance occurs."Our findings suggest that gefitinib resistance that is caused by MET overexpression is at least partly due to miRNA deregulation, " says principal investigator Carlo Croce.

BEIJING, Nov. 13 (Xinhua) -- A campaign that aims to boost the public's role in safeguarding food safety and promote awareness of the issue was launched at the 9th China Food Safety Annual Conference, which closed on Sunday.Food safety has a bearing on people's health as well as the nation's sound and harmonious development, said Shi Xiushi, chairman of the Financial and Economic Committee of China's National People's Congress (NPC), at the opening, calling for efforts to raise companies' sense of responsibility and consumers' awareness in preventing and dealing with food safety crimes.The new campaign is part of a broader five-year program (2011-2015) of food safety education announced by the State Council Food Safety Commission (SCFSC) in May.The program aims for more than 80 percent of the public to be aware of basic food safety by 2015, with the rate for primary and high-school students reaching up to 85 percent or more.ARDUOUS WORKFood safety has become a growing public concern in China following a string of scandals over recent years. In the latest one, illegal workshops were found making and selling "gutter oil," which is processed from leftovers dredged from gutters.Gu Xiulian, former vice chairwoman of the NPC's Standing Committee, the country's top legislature, said ensuring safety is the top priority for the food sector, the country's pillar industry with an output of 550 million yuan (97.3 million U.S. dollars) in the first nine months of 2011.The development of the nation's food safety has failed to keep up with the demands of a public whose living standards have improved substantially in recent years, said Shi.Pledging to do everything it can to ensure food safety, the government takes a zero-tolerance approach to companies that sell unsafe food. In 2010 alone, authorities across the country investigated and handled 130,000 cases of food safety violations, shutting down more than 100,000 companies, according to the SCFSC."The food industry's overall development level is relatively low. There are weak links in the sector's credibility, management, detection techniques and even the laws and regulations," said Pu Changcheng, deputy director of the Administration of Quality Supervision, Inspection and Quarantine.Pu's points are exemplified by China's agricultural industry, which is largely based around small-scale production managed by disparate bodies. It would be a formidable task to eradicate the sector's safety issues.The catering business also faces a similar plight. The country has issued licenses to 2.2 million catering companies, most of which are small and individually operated, making safety supervision extremely difficult, according to Bian Zhenjia, deputy head of the State Food and Drug Administration.

XIAMEN, Dec. 26 (Xinhua) -- The three-decade achievements of the Xiamen Special Economic Zone have shown that China has made the right decision to set up special economic zones (SEZs), President Hu Jintao said Monday.Hu made the remarks in a congratulatory letter to a gala held Monday in southeastern Fujian province's city of Xiamen, which is celebrating the 30th founding anniversary of its special economic zone.Over the past 30 years, the Xiamen Special Economic Zone has made marked socio-economic progress, made significant changes in people's lives, and served as a pilot area for the country's reform and opening-up and socialist modernization, Hu said.The Xiamen Special Economic Zone has made a unique contribution to promoting cross-Strait economic and trade cooperation as well as culture and personnel exchanges, Hu said in the letter.Hu also urged the economic zone to further enhance the capability of independent innovation, ensure and improve people's well being, strengthen and make innovations in social management, and better serve the peaceful development of the cross-Strait relationship.He Guoqiang, a member of the Standing Committee of the Political Bureau of the Communist Party of China (CPC) Central Committee, attended and addressed the gala.In his speech, He said the economic zone should develop high-end manufacturing business and a modern service industry, while speeding up the establishment of a market-oriented technology innovation system that integrates production with scientific research.The economic zone needs to make greater efforts in energy saving and emissions reduction as well as environmental protection by greatly developing a green and recycling-based economy, according to He.He also said that the economic zone should exert itself to increase the income of rural and urban residents, especially low-income residents, and meet people's basic requirements in terms of education and culture, employment, medical services and housing."Reasonable appeals of the people should be addressed, and behavior that undermines people's interests should be resolutely rectified," He said.In addition, He expects the Xiamen Special Economic Zone to thoroughly implement the cross-Strait Economic Cooperation Framework Agreement (ECFA) and further explore and enhance cooperation in finance and logistics with Taiwan, He said.The economic zone should also strengthen the development of direct flights, customs clearance and ports in order to facilitate direct exchanges across the Taiwan Strait, according to He.He also met with representatives of Hong Kong, Macao and Taiwan residents and overseas Chinese, who attended the gala.He said people from all walks of life in Hong Kong, Macao and Taiwan have long been active in investing, financing education and alleviating poverty in Fujian.They have not only shared the opportunities that the country's reform and development have brought forth and expanded their own enterprises, but also greatly boosted the country's socio-economic progress, He said."You are witnesses, participants and beneficiaries of the reform and opening up," He said to these representatives.The Xiamen Special Economic Zone is one of the four earliest SEZs set up after China initiated the reform and opening up in 1978. In 1984, it was expanded from the initial 2.5 square kilometers to 131 square kilometers. Last year, it was extended to span the entire city.

BEIJING, Oct. 25 (Xinhua) -- Chinese State Councilor Dai Bingguo said Tuesday that China will unswervingly pursue a path of peaceful development and play a constructive role in the United Nations.Dai made the remarks at a reception commemorating the 40th Anniversary of the restoration of the lawful seat of the People's Republic of China in the United Nations (UN).On Oct. 25, 1971, the 26th Session of the UN General Assembly adopted Resolution 2758 with an overwhelming majority and decided to restore the lawful seat of the People's Republic of China in the UN."This opened a new chapter in the external relations of the People's Republic of China and promoted the friendship and cooperation between China and all countries and peoples who love world peace and justice," Dai said at the reception hosted by the Foreign Ministry in Beijing.It also enhanced the universality, representativeness and authority of the UN and strengthened the forces for world peace and human progress, he added.He said, for the past 40 years, as the largest developing country and a permanent member of the UN Security Council, China has followed the purposes and principles of the Charter of the United Nations, called on countries across the globe to practice tolerance and live together in peace as good neighbors, and made great contributions to world peace, common development and international cooperation.This year marks the beginning of the second decade of the new century, and the world has undergone great, rapid and drastic changes, Dai said."The international community is becoming a global village and countries find interests converging in a scope and depth never seen before," he said, adding that the trend of peace, development and cooperation has gained more popular support, while the international situation remains quite fluid and complex.He said the United Nations, as the most universal, representative and authoritative inter-governmental organization, should seize opportunities and meet challenges in the political, security, economic, development, social, humanitarian, cultural, arms control, and judicial fields, among others, and reinvigorate itself with fresh vigor and vitality."Under the new circumstance, the role of the UN should only be strengthened, rather than weakened, and its authority be upheld, rather than impaired," he said.China has released the White Paper on China's Peaceful Development, which solemnly declared that China will unswervingly pursue the path of peaceful development, he said.China will work actively, through peaceful, open, scientific and common development, to expand international cooperation, take part in international affairs, honor its due international responsibilities and obligations, and play a constructive role in the UN, he said.Dai pledged that China will join other countries to make even greater contributions to building a harmonious world of durable peace and common prosperity and a brighter future for mankind.China's entry to the UN 40 years ago made the international body a more representative international organization, said Kasymzhomart Tokaev, director-general of the UN Office at Geneva.He said China has played an important role in the UN.With the rise of its global status and influence, China, as a major power, will continue to shoulder its responsibility and play a more positive role in creating a more secure, just and peaceful world for future generations, he said.Before the reception, Dai had a brief meeting with Tokaev, exchanging views on the UN's role as well as China's cooperation within the UN.

BEIJING, Jan. 10 (Xinhua) -- China's energy chief said here Tuesday that the country is under greater pressure to ensure energy supply this year as both demand and international competition for resources grows.Liu Tienan, head of the National Energy Administration (NEA), made the remarks when speaking at a national energy work conference."It is always worrisome to have to sustain supply of energy and resources for a country with 1.3 billion people," Liu said.As China is facing a "grim situation" in energy saving and emission reduction, Liu noted, it is urgent to restructure the country's energy use and control the gross consumption volume this year.To ensure a stable energy supply, China will optimize the layout of energy exploration, start construction of energy-transmission projects and other major energy programs while boosting reserves of oil, natural gas and coal in 2012, Liu said.The NEA plans to add another 200 metric tons to the country's coal-producing capacity this year plus 70 million kw of new installed power-generating capacity.If the ecology is protected and people are relocated, China will start construction of hydropower projects of 20 million kw in 2012, according to the NEA.Once safety is ensured, nuclear power will be developed after the country's new safety plan is approved.As for renewable energy development, the NEA plans to launch wind power projects with a total capacity between 15 million kw and 18 million kw, while developing 3 million kw of solar power over the new five-year period ending 2015.Liu said, in 2012, the country aims to provide electricity to another 600,000 people who currently have no access to it and expand electricity access to 5 million people by 2015.The NEA has budgeted 65 billion yuan (10.3 billion U.S. dollars) for upgrading the grids in rural areas.Over the next four years, China will facilitate the development of non-conventional natural gas, such as shale gas and coalbed methane by increasing the number of natural gas users by 100 million to 250 million.A key indicator measuring the economic vitality, power consumption rose 11.7 percent year-on-year to 4.7 trillion kWh in China in 2011. The growth in 2012 is expected to slow to 8.5 percent amid the country's economic slowdown.

来源：资阳报