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SAN DIEGO (KGTV) — Two separate clinical trials for phase three COVID-19 vaccines will resume in San Diego next week after AstraZeneca and Johnson & Johnson paused their students to find out why some participants became ill.“Pauses like this are absolutely common in large phase three trials so people should not be alarmed,” said Dr. Susan Little, the trial director for both studies that UC San Diego is set to take part in. “Studies will only resume when they are deemed safe for the study participants.”Little said not only are pauses like this common, but they also prove that the safety review process is working as it should.“Part of the reason we want people to understand that these are common is they will probably occur again, AstraZeneca with 30,000 people, Johnson & Johnson 60,000 people. It would be surprising if we don’t have another pause,” she explained.Little said once a trial is paused, it is immediately investigated by the independent Data Safety and Monitoring Board (DSMB). The board reviews the issues and determines if they are related to the trial.“In this case, the event and all other safety events were reviewed and deemed not related,” she said.The AstraZeneca study is scheduled to start on Monday, and UCSD will be using a mobile vaccine clinic that will travel from Chula Vista, La Mesa, and Imperial Beach.The Johnson & Johnson study is scheduled for Tuesday in National City, where trailers have been set up as a clinic at El Toyon Park.“We are signing people up right now to have scheduled visits next week,” said Little. “Safety will always remain the number one priority for study participants.”Those interested in participating in the study can sign up here.Participants must be 18 years or older and in generally good health. People with underlying health conditions like heart disease or lung disease may participate.“They just need to be relatively stable with their conditions,” said Little. 1957

SAN DIEGO (KGTV) - Two children suffered injuries Monday when a pick-up truck driven by an elderly man hit tables and parked cars outside a University City Starbucks.The crash happened about 8 a.m. outside the coffee shop at 3202 Governor Drive at Regents Road, according to San Diego Police. The Starbucks is near the University City Post Office.The 85-year-old man driving the truck jumped the curb, crashing into customers.A 6-year-old girl was taken to the hospital with unknown injuries. Police did not release details about her condition. A 2-year-old girl had an injury to her lip but did not need further treatment.San Diego Police have not announced what caused the crash. 689

SAN DIEGO (KGTV) -- InCahoots Dance Hall and Saloon in Mission Valley is usually packed with country music lovers  line dancing, two stepping and always having a great time.But on Monday nights, the dance floor is cleared out. The atmosphere goes from being country to cathartic. "I thank God for this group," said Lisa Como. Como is a member of a unique group. They all survived the massacre at Route 91 Harvest Festival in Las Vegas last October. The group estimates there are roughly 300 survivors across San Diego County and Temecula. They gather weekly to share their flashbacks and their fears. "All I remember, was thinking I just don't want to get shot in the back," said Como. "I just don't want to get shot in the back."Delanie Leone says people started dropping all around her. "We knew it was gunshots because the lady in front of us was shot and went down immediately. I'm not a nurse, I'm not an EMT. I just went into crisis mode," said Leone. Como said memories from that awful night haunt her every day. "I was driving down the road and I looked over at a car and I was like, oh my God, he could start shooting at me right now, and then I realized she had the same thoughts," said Como. A clinical psychologist for the navy leads the group in their healing and recovery. Dr Shiva Ghaed has spent decades treating veterans who suffer from PTSD.  She knew there would be countless survivors who are also vets. "Country music it appeals to, it's military heavy. I was really heartbroken thinking about the fact that this massacre happened to a group of people that are already previously exposed to an increased amount of trauma." said Dr. Ghaed. "I knew there would be thousands, and thousands and thousands and thousands of people that would have invisible injuries."She knows just how much those invisible injuries can hurt. She is also a survivor of the massacre."Honest to God, I don't know how I lived because I was in the kill zone, I was in the line of fire," said Dr. Ghaed. "People all around me were shot and killed and I just had to find some purpose and meaning in surviving that."  She's finding much of that purpose by leading the weekly therapy groups.  "I really think that that's how you make it a better world. If everybody steps up when they can, in the way that they can, and gives back it can be a better world," said Dr. Ghaed. Taylor Winston is a San Diego Marine who also lived through the shooting rampage. He made national headlines when he grabbed a truck and drove into the gunfire to save dozens of victims. Winston helped start the weekly support groups. "It means a lot to me to leverage whatever short term fame I was given throughout the whole massacre to put Shiva in front of people," said Winston. As people begin to emotionally heal, they're beginning to question the events of that night. "A lot of people are feeling left in the dark with the media moving on and kind of forgetting about us and just kind of seeing lack of security in the hotel," said Winston. "Just trying to prevent something similar from happening in the future."None of the survivors in this particular group have filed a lawsuit, but they are beginning to consider it."I don't think anyone is trying to get money out of it for any personal gain, but at the end of the day so many people were mentally affected by this, they've lost jobs, they've lost scholarships and sad to say people need money to stay afloat," said Winston. Recently, a new group calling itself Vegas Protest 4 Truth held a protest outside the Las Vegas Police Department's headquarters. The group wants the audio of the 911 calls to be released, along with all surveillance footage and body cam video related to the October 1st shooting that killed at least 58 people and wounded hundreds.  They're also demanding the release of search warrant findings and sealed court documents. "With such little information, everyone's mind is going to wander and think conspiracy and that's honestly a fair thought for a lot of people," said Winston. "A lot of it doesn't make sense and people are starting to recover and get mentally strong and ask questions." Right now, their focus remains on recovery. San Diego survivors are working with survivors across the country to help them start similar support groups. "I think of country strong as this, I see the faces. I see the strength that we've come up together," said Jason Zabala.More information about the local survivors group can be found here:  route91sd.com.   4787

San Diego (KGTV)- A local middle and high school team sweep a popular robotics competition beating out groups from all over the world.They call themselves “Team Inspiration.” The group of students has been working with robotics for nearly ten years.The team is comprised of six different schools in San Diego, including: Del Norte High, Scripps Ranch High, Rancho Bernardo High, Westview High, The Cambridge School, and Black Mountain Middle School.Last month the team competed in the 2020 International RoboSub Competition. Each team had to build an underwater robot.“The basic tasks include going underwater, seeing and recognizing images underwater, and going to wave points underwater,” says team member Colin Szeto.This Is the second year the group participated in the competition. Due to COVID-19, the competition was done virtually this time around.“It was a pretty good equalizer because we all got the same zoom playing field,” says Aditya Mavalankar.The student updated their robot design from last year and built an additional robot for the competition.“The idea was that both of them would go in the water together to distribute the tasks so that we could have more of an advantage,” says Ashiria Goel.The students also built the sensor navigation parts on the devices. It can “basically tell how far it is from other objects,” says Mavalankar. “We have cameras on multiple sides of the robots. We have hydrophones that’’s able to create an acoustic pinger in the pool.”Team Inspiration took home first place in the overall competition, technical design, and website. The team came in second place in the video presentation category.Team inspiration is the only middle and high school team to ever win the world title in RoboSub’s 23-year history. 1767

SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906