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LONDON (AP) — AstraZeneca and Oxford University have acknowledged a manufacturing error that is raising questions about preliminary results of their COVID-19 vaccine.A statement Wednesday describing the error came days after the company and the university described the shots as “highly effective” and made no mention of why some participants didn’t receive as much vaccine as expected.In a surprise, the group of volunteers that got half a dose in the first of their two shots seemed to be better protected than the volunteers who got full doses. The low-dose group was smaller and younger, however, which could have skewed the results, experts say.In a statement obtained by CNN, Oxford elaborated further, saying that a “difference in the manufacturing process” had led to the error.The university said that it discussed the problem with regulators, agreed to complete the late stage trial with two groups, and the problem has since been corrected. 959

LOS ANGELES (CNS) - An autopsy could be conducted as early as Monday on award-winning former USC offensive lineman Max Tuerk, who died while hiking with his parents on a favorite trail in the Cleveland National Forest. He was 26.Tuerk was pronounced dead at 3:14 p.m. Saturday at Mission Hospital in Mission Viejo, according to Supervising Deputy Orange County Coroner Erica Arellano. There was no immediate indication of an apparent cause of death, Arellano said.Tuerk was the first-team All-Pac-12 center as a junior in 2014. He started the first five games at center in 2015, then tore ligaments in his right knee and underwent season-ending surgery. Despite the injury, he won USC's Most Inspirational Player Award.Tuerk was a captain both of his final two seasons with the Trojans.Tuerk started USC's final five regular-season games at left tackle as a freshman in 2012 and at left guard in its 21-7 loss to Georgia Tech in the Sun Bowl.Tuerk started 13 games at left guard and one at right tackle in 2013, receiving All-Pac-12 honorable mention."Heartbroken by the loss of Max Tuerk," Trojans coach Clay Helton tweeted. "Incredible person, teammate, and Trojan. Our thoughts and prayers go out to his family."The 6-foot-5, 298-pound Tuerk was chosen by the San Diego Chargers in third round of the 2016 NFL draft, the 66th overall selection. He was inactive for all 16 of the team's games in 2016, their last in San Diego.Tuerk was suspended by the league on Aug. 22, 2017, without pay for the first four games of the regular season, for violating the NFL policy on performance-enhancing substances."This off season, I made the mistake of taking over-the-counter supplements," Tuerk said. "In doing so, I opened myself up to the possibility of consuming a tainted supplement -- something that ultimately led to a positive test for a banned substance."I accept responsibility for my actions and understand the NFL's policy is very clear on this matter. This is a very hard way to learn a lesson and I will never make this mistake again."The Chargers issued a statement saying they "respect and support the league's decision on this matter. While disappointed, we appreciate that Max has accepted responsibility and are confident that he understands what is expected from him moving forward."The Los Angeles Chargers waived Tuerk on Oct. 3, 2017, one day after he became eligible to return to their active roster because the team was "pleased with the guys that we have," coach Anthony Lynn said.The Chargers signed Tuerk to the practice squad Oct. 26. The Arizona Cardinals signed Tuerk off the Chargers' practice squad on Nov. 6, 2017. He played in his lone NFL game on Dec. 24, 2017. He was released by the Cardinals on April 12, 2018.Tuerk was an alumnus of Santa Margarita High in Orange County's Rancho Santa Margarita and was selected to various All-America teams as a senior in 2011."Max loved his teammates, coaches and schools," his family said in a statement. "Max was a loving son and older brother and his passing leaves a giant hole in our hearts. His strength and work ethic is an inspiration to many." 3129

LONG BEACH (CNS) - A crane toppled over and struck a house in Long Beach Monday, injuring a homeowner who was hit by debris.Crews were working on overhead lines about 12:30 p.m. in the 300 block of 61st Street when the crane fell between two houses, striking the rear portion of one of the homes, according to Long Beach Fire Department Capt. Jack Crabtree.The injured homeowner, who had been working outside when the crane fell, was conscious and in stable condition when taken to a hospital, the captain said.The street was closed between Elm and DeForest avenues as crews worked to dismantle the crane. 613

LONDON (AP) — Oxford University says trials of a coronavirus vaccine that it is developing with pharmaceutical company AstraZeneca will resume, days after being paused due to a reported side-effect in a patient in the U.K. The university said in large trials such as this “it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety.” It said globally 18,000 people have received the vaccine so far. Oxford insisted that it is “committed to the safety of our participants.” Pauses in drug trials are commonplace. The Oxford-AstraZeneca vaccine is seen as one of the strongest contenders among the dozens of coronavirus vaccines being tested. 728

LOS ANGELES (AP) — Health officials say the number of coronavirus cases in California is surging to the highest level since the start of the pandemic. The California Department of Health and Human Services reported more than 15,000 cases Saturday and another 14,000 cases on Sunday. They come even before the Thanksgiving holiday that has many health officials concerned. A curfew took effect Saturday requiring people to stay home from 10 p.m. to 5 a.m. affecting most Californians, and Los Angeles is on the verge of an even tougher lockdown. Meanwhile, more than 200 people at a San Francisco Bay Area racetrack have tested positive. 644

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