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WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy to E. coli derived asparaginase and pegapargase chemotherapy drugs used to treat ALL.Acute lymphoblastic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell. White blood cells help the body fight infection and are formed in the bone marrow.Erwinaze is injected directly into the muscle three times a week and works by breaking down one of the body's protein building blocks (the amino acid, asparagine) that is present in the blood, and is necessary for the growth of all cells. Leukemia cells cannot produce this protein building block. When a patient is treated with Erwinaze the leukemia cells die. Normal human cells are able to make enough asparagine for their own needs through biosynthesis and will not be affected by treatment with Erwinaze."The approval of Erwinaze underscores the FDA's commitment to the approval of drugs for conditions with limited patient populations with unmet medical needs using novel trial endpoints," said Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research.Side effects associated with Erwinaze treatment include serious allergic reactions, inflammation of the pancreas, high blood levels of liver enzymes, blood clotting, bleeding, nausea, vomiting and high blood sugar.

SHANGHAI, Jan. 11 (Xinhua) -- China has allowed the Bank of East Asia (BEA) to issue yuan-denominated bonds in Hong Kong for a second time, about three years after it became the first foreign-invested bank to make a yuan bond issuance, the bank said Wednesday.BEA China Ltd, a wholly-owned subsidiary of the BEA, was given the approval by the National Development and Reform Commission of China to issue yuan bonds in Hong Kong, it said.Details on the amounts and timing of the offerings weren't available. In 2009, in a major landmark, the BEA issued its first yuan bonds in Hong Kong in an aggregate principal amount of 4 billion yuan (630 million U.S. dollars).The BEA was among the first foreign-invested banks to be given the green light to issue yuan-denominated bonds in Hong Kong, a move analysts say will bolster the international influence of the Chinese currency, also known as renminbi.Sun Minjie, deputy head of BEA China, said the second bond issuance will give the bank stable access to capital, improve its debt portfolio, and support its development on the Chinese mainland.

BEIJING, Jan. 26 (Xinhua) -- China will firmly stand together with African countries while unswervingly pushing forward Sino-African strategic partnership, no matter how the international environment changes, said Chinese Vice Foreign Minister Zhai Jun Thursday.Zhai made the remarks in a signed article on top Chinese political advisor Jia Qinglin's upcoming visit to Africa.Africa still faced enormous challenges against the backdrop of simmering global finance crisis, and turbulence encountered by several countries in western Asia and northern Africa, which dealt a blow to Africa's peace, stability and development, Zhai said, adding that some outside forces' intervention into Africa's internal affairs impeded the integration process among African countries.Within this context, there is stronger demand of African countries for stability, development, solidarity and independence, he said.The international community should pay more attention to Africa's voice and problems, respect its opinions, accommodate its concerns, protect peace, stability and development in Africa, and support Africa's independent settlement of issues in its own region, Zhai said.He said Jia's visit, first foreign trip paid by Chinese leaders in the Chinese Lunar New Year, will be of great significance in deepening Sino-African ties and cementing the solidarity and cooperation among developing countries, Zhai said.Jia will declare China's determination on developing Sino-African ties during the trip, he said.Enhancing solidarity and cooperation with Africa constitutes an important part of China's diplomacy, and will be the long-term strategic choice firmly pursued by China, Zhai said.

CAPE TOWN, Nov. 13 (Xinhua) -- The research vessel SA Agulhas has set off from Cape Town on a 10-day polar tour intended to promote dialogue on climate change, authorities confirmed on Sunday.The trip was designed to mark the 17th Climate Conference of the Parties (COP17) to be held in Durban later this month, according to the Department of Environmental Affairs.The voyage, which set off Saturday noon with scientists, academics, students and journalists aboard, would host exhibitions, symposiums and lectures from climate change scientists on the work of the polar research vessel, spokesman Zolile Nqayi said in a statement.The exhibitions and lectures would also highlight the various scientific activities undertaken by the department and its partners in Antarctica and the Southern Oceans, according to the South African Press Association (SAPA).Apart from her research and supply work, the Agulhus also helped to rescue the Magdalena Oldendorff, which became stuck in thick ice in June 2002.In December the SA Agulhas would make its final voyage to Antarctica before retirement.The Agulhas, which has been in service for 33 years, would be replaced by a new vessel under construction in Finland."She served us very well," said Dr Monde Mayekiso, deputy director general of oceans and coasts."The new vessel will have enhanced technologies and capabilities to further understand the ocean environment and to bring that understanding to an increasing number of South Africans, " he said.

LOS ANGELES, Oct. 3 (Xinhua) -- An organizer of the World Stem Cell Summit says one of the key problems medical researchers face these days is how to apply their findings in the real world."How do you take the phenomenal scientific research going on in labs and translate it into medical treatments,?" said Bernie Siegel, the founder and co-chair of the summit and executive director of the Genetic Policy Institute, which organized the event."It's a big job to do this, and more than just the science," Siegel said, noting that in a growing field now moving beyond basic lab research, the aim is to connect the people who do the work with those who finance it.The three-day summit, which opened Monday in Pasadena, features more than 150 top international speakers and 50 hours of programming with leaders from science, pharmaceutics, business, policy, ethics, law and other fields.The cell therapy industry, a "nascent" field, has emerged to be a potentially multi-billion business with unlimited potential, Siegel said.Stephen Dalton, a University of Georgia professor, reported that one of the biggest developments in stem cell research in the past year was the realization that cells can be transdifferentiated from one state to another without returning to a pluripotent state.Dalton said the principle was previously supported by a few isolated examples but it was not until 2010 that the idea was widely accepted.Mark Sussman, a professor from San Diego State University, called the identification of lung stem cells from human tissue samples capable of regenerating the highly complex and specialized structures of mature lungs a breakthrough in lung biology and regenerative medicine.He said results presented by the Anversa group in the New England Journal of Medicine demonstrate that human lung stem cells can be expanded in vitro and also retain the capacity to integrate into adult tissue upon introduction into mice.The study, Sussman said, has opened up an entirely new field of possibilities for lung regeneration and potential therapeutic applications for many conditions where treatment options are either very limited or nonexistent.