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Johnson & Johnson is beginning a huge final-stage study to try to prove if a single-dose COVID-19 vaccine can protect against the virus. It will be one of the world’s largest coronavirus vaccine studies so far, testing in 60,000 volunteers in the U.S., South Africa, Argentina, Brazil, Chile, Colombia, Mexico and Peru. A handful of other vaccines in the U.S. and elsewhere are already in final testing. The two other vaccine candidates in final-phase testing in the U.S. — candidates made by Moderna and Pfizer — were both approved in July. Earlier this month, Dr. Anthony Fauci said those trials should be filled by the end of September, meaning they should be completed by late November or early December.Hopes are high that answers about at least one could come by year’s end, maybe sooner. U.S. health officials insist the race for a vaccine isn’t cutting corners, despite enormous political pressure. 918

LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

KANSAS CITY, Mo. -- Virginia Merritt always wanted to be a mom. “We were like, okay, we’re going to be married for a year, enjoy being newlyweds and then right at a year stopping birth control,” she said, looking at her husband, Dustin Merritt, with a glint in her eye.Virginia and Dusty started “trying” right around their one-year anniversary, exactly as they’d planned. Except, things didn’t go as planned.“Those first few months we knew it was early. Probably the three-month mark is when we were like...hmm, what’s going on,” she said.It seemed like all their friends were having babies. Several members of their family were having babies.They were happy for those announcing births and celebrating babies, but that happiness was muted.They found themselves staying home more. They were sad. They wanted so badly to be parents. 845

Joe Biden was officially nominated as the Democratic nominee for president on Tuesday at the virtual Democratic National Convention. Delegates cast their votes virtually as the in-person convention was canceled due to the coronavirus pandemic. Tuesday's roll call was merely a formality as Biden accumulated more than 50% of pledged delegates during the primaries. Biden is now the nominee-in-waiting, and he will accept the party's nomination on Thursday from Wilmington, Delaware. 490

Just got off phone with @realDonaldTrump who has approved our Major Disaster Declaration request.Grateful for his quick response. https://t.co/rF7VFqSENl— Gavin Newsom (@GavinNewsom) October 16, 2020 207