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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

Tesla is disputing claims by a California man that all three models of the company’s cars can suddenly speed up on their own without the driver touching the accelerator pedal.Tesla said Monday it checks when drivers report that their car accelerated on its own, and in every case where the company has the car’s data, it drove as designed.The company also claimed the man who filed a petition with federal safety officials is a short-seller of Tesla shares, referring to investors who borrow shares in a company’s stock and try to profit by replacing them after the share price falls.On Friday, the National Highway Traffic Safety Administration said it would look into a petition filed by Brian Sparks of Berkeley, California, and decide whether to open a formal investigation. Sparks’ allegations cover about 500,000 Teslas, including Model 3, Model S and Model X vehicles in model years 2013 through 2019.Sparks said Tesla owners have lodged 127 complaints with the government, covering 110 crashes and 52 injuries.Tesla, which did not respond when asked for comment on Friday, posted a statement Monday saying its electric vehicles do not accelerate on their own.The company called the petition “completely false,” adding that “the car accelerates if, and only if, the driver told it to do so, and it slows or stops when the driver applies the brake.”Sparks said in his 69-page petition that many of the Tesla accidents happened during parking, that the complaint rate was much higher than for other vehicles, and that Tesla refused to share the car’s data with owners after incidents.The highway agency has yet to verify the complaints. The people who filed complaints were not identified in NHTSA’s database. 1726

The Dow Jones traded below 20,000 for the first time since 2017 on Tuesday, but appeared to have stemmed some of the bleeding after Monday's 3,000 point loss.After an early peak, the Dow sunk about 200 points shortly after opening, leaving the markets trading at less than 20,000. But as Trump administration officials spoke about their plan to give 362

Thanksgiving is a time to be with friends and family, but if that’s not an option for you this year, there are some alternatives that won’t cost you too much. Cracker barrel is definitely a fan favorite. The restaurant chain offers a classic Thanksgiving meal. All you have to do is order it 24 hours in advance, pick it up that morning and serve up that afternoon. The cost is just per person.Marie Calendars has five Thanksgiving feasts to choose from, all of which require about three hours of reheating time. The turkey option is the least expensive at and it includes all the trimmings and their famous pies. If you're someone who is OK with going without dessert, Boston Market might be for you. For , they are offering a turkey dinner that serves six people – just enough for leftovers.If you have a Costco membership, the big box store is making your life easier. For , the meal serves eight people. That means you will have a lot of leftovers. You have to order soon, because it ships to your house frozen.Now, if you're willing to spend a bit more and get a meal created by a celebrity chef, Whole Foods is where to go. For per person, you get turkey, all the fixings and even dessert. 1226

The one bright spot: Our holiday crook didn’t get away with the wheelchair. Heroes on the train came to the rescue, getting the chair back within seconds. Let’s catch him! Tips to https://t.co/hF4eXJ45F8. pic.twitter.com/EzR92qIGUP— Phoenix Police Department (@phoenixpolice) December 7, 2019 305