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SAN DIEGO (KGTV) -- San Diego resident Jenifer Raub describes herself as a fighter.“I just don’t give up. If I see a window, just a little crack in the doorway of opportunity, I’m going to jump on it," said Raub.She never imagined to find herself in the fight against Parkinson's Disease, a progressive nervous system disorder which affects movement and has no cure.“For me, it was I had a hard time walking, but it was real intermittent, it just made no sense, and then my hands started to shake," said Raub.In the beginning, Raub refused to believe the diagnosis, eventually finding a doctor who told her what she wanted to hear."He told me I didn’t have the disease and he told me to go off all those medications you're fine. I did, and I couldn’t walk at all at that point.”So Raub shifted her fight towards finding a cure for Parkinson's.She's now president of the Summit for Stem Cell Foundation, a nonprofit created to support the use of stem cells to treat Parkinson’s; research underway in Dr. Jeanne Loring’s Torrey Pines lab. “We’re right on the edge of a revolution, in which these particular cells, because of their power and our ability to manipulate them, are going to change the way medicine is done," said Dr. Loring.Her research focuses on pluripotent stem cells, the remarkable cells that self-renew and can give rise to every cell type in the body.Parkinson’s Disease breaks down and eventually kills certain nerve cells in the brain, dopamine neurons that affect movement. Dr. Loring's team is working to transform patient's skin cells into pluripotent cells which can then become dopamine neurons. “We plan to transplant those cells to the brains of people with Parkinson’s to replace neurons they’ve lost," said Dr. Loring. Because the cells come from the actual patient, they are a perfect match which the body will not reject. After the implant, Dr. Loring says over time they'll make connections and restore circuits that have been broken by the loss of dopamine neurons. Patients, she says, will likely start seeing changes in their symptoms in six months. Dr. Loring believes the treatment could also work for other diseases like Alzheimer's and Multiple Sclerosis. ‘These diseases are not going to able to be treated with a conventional drug that you take, it's going to have to be more sophisticated than that, and I think this opens the opportunity for really scientifically-based, knowledge-based therapies. Stem cells are medicines; we can't forget that. They're living drugs," said Dr. Loring.Her team has already proven the treatment works in animals. Now they're waiting on FDA approval for a clinical trial of 10 patients, Raub will be one of them. Raub is also a patient advocate and works tirelessly to fundraise for Summit for Stem Cell Foundation. "The disease is a progressive disease and their [patient's] time is of the essence, it's critical to people with Parkinson’s. The disease does not wait for an answer, it just keeps going," said Raub.Raub says she won't stop either, on behalf of all the patient's up against time. 3077

SAN DIEGO (KGTV) -- SeaWorld San Diego plans to close Thursday as the county prepares for a storm. According to a news release, the theme park made the decision due to heavy rain and strong winds that could sweep through San Diego. The park plans to re-open Friday, November 30. Showers are expected to develop Wednesday night, becoming widespread and heavier by Thursday. Rainfall totals are expected to average between .50” to 1.50” for the coast and valleys with 2” to 4” in the mountains and .50” in the deserts. Strong winds will also accompany the storm. A wind advisory is in effect for the coast and valleys Thursday from 8 a.m. to 6 p.m. and for the mountains and deserts from 6 a.m. Thursday through 6 a.m. Friday. Click here for a look at the full forecast. 777

SAN DIEGO (KGTV) -- Some San Diegans are pushing back against the county’s order to wear face coverings in public.The face coverings requirement in San Diego County -- prompted by the COVID-19 pandemic -- has been in effect since early May, but in other California counties, rules are starting to change.Last week, Orange County officials decided to roll back their mandate and only “strongly recommended” that masks be worn in public settings.Riverside and San Bernardino counties have also relaxed their respective mask mandates.“It's a hard thing to draw the lines. There’s human nature, there’s a concern about such a ramp-up of state enforcement of things,” said University of St. Thomas Law School Professor Robert Kahn.Kahn, an expert in mask law and history, said one of the biggest issues is people are not used to taking orders from health officials.That feeling is evident in social media postings on pages like Reopen San Diego on Facebook, where there is a growing push to rescind San Diego’s mask mandate.Many health officials still agree that face coverings can block transmission of the respiratory droplets released by people when breathing or talking.During a Monday press briefing, San Diego County Public Health Officer Wilma Wooten said, “Every jurisdiction is different, but San Diego will continue mandatory face coverings.”Kahn said no matter what rules or laws government might put in place, people will ultimately have to abide by what businesses want their customers to do.“Businesses will make their decision; private business, free enterprise understands this,” he said.Orange County’s public health officer resigned rather than remove the county’s mask order. The OC supervisors then replaced her with someone who would make that change.California officials recommend face coverings, but they leave the final decision up to individual counties. 1882

SAN DIEGO (KGTV) — San Diego Symphony has already revealed the sounds that will fill the air outside the San Diego Convention Center this summer.During Comic-Con 2019, the symphony will perform music from the cult-galactic adventure "Galaxy Quest," on July 19, and "Back to the Future," on July 20, at Copley Symphony Hall. Both performances will be led by composer David Newman, who composed the score for "Galaxy Quest" and other films including "Ice Age," "Matilda," and "Bill and Ted's Excellent Adventure" and following "Bogus Journey."FOLLOW SDCC 2019 NEWSIn town before the convention kicks off? You can catch the musical fun the weekend before as the symphony performs the score from "Harry Potter and the Half-Blood Prince."Tickets have yet to go on sale for any of the concerts, but can be purchased here when available. Last year, ticket prices ranged from - .The concerts continue the symphony's tradition of off-site performances coinciding with the buzz surrounding San Diego Comic-Con. Last year, the symphony performed music by famed film composer John Williams, including scores from "Star Wars," "Jurassic Park," "Indiana Jones," "Harry Potter," and more.Comic-Con returns to San Diego July 18 - 21. 1232

SAN DIEGO (KGTV) -- Starting Wednesday, cruise ships will return to the San Diego Embarcadero — but they will not be picking up any customers for months to come. Experts say the longer the vessels stay, the harder it is for the cruise industry to bounce back.The Holland America Koningsdam returned to the Port of San Diego Wednesday morning. It is one of five cruise ships scheduled to dock at the Embarcadero for fuel and supplies. But not to pick up guests.The vessels include:Holland America Koningsdam – December 23Princess Cruises Emerald Princess – December 24 (leaves for Los Angeles after San Diego visit)Holland America Westerdam – December 28Holland America Zuiderdam – January 8Holland America Noordam – January 11"Their revenues compared to say the same time last year are literally down 99%," financial advisor Dennis Brewster said.According to the Port of San Diego, there have been 119 canceled cruises since March and a loss of 0 million in regional economic activity. Unlike airlines and restaurants, which are two other industries hard hit by the pandemic, Brewster says cruises have no Plan B."Their revenues literally went to zero," Brewster said. "I mean, the others were really bad too, but you can't do a cruise ship on a takeout or drive-through."The Port says each cruise line must follow the CDC's "Framework for Conditional Sailing Order" before they can set sail. The first phase is to test and safeguard the crew. The second is a simulated voyage where the ships must prove their ability to mitigate COVID-19 risk. After that, they can slowly reintroduce passengers on their voyages.In the meantime, the ships and crews will stay put. But will the companies be able to stay afloat?"Even if the CDC and other organizations say, 'January one, you can resume your operations,' how many people would get on today?" Brewster asked.The hope is that travel will be on everyone's radar once it shifts away from the coronavirus."I think all of us have spent enough time at home the last nine months to last the next nine years," Brewster said. "So that's a good thing for the industry. There is going to be quite a bit of pent-up demand."According to the Port of San Diego, Holland America has some cruises scheduled to depart in April and May. However, they will only be able to set sail if they get their certifications from the CDC. 2367