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发布时间: 2025-06-01 04:25:59北京青年报社官方账号
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WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.

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BEIJING, Jan. 9 (Xinhua) -- China's official website for booking train tickets received a daily average of more than 1 billion hits during the first week of January, according to a railway official.Hu Yadong, vice minister of railways, said Sunday that the online ticket sales platform has provided consumers with a convenient way to buy tickets. He also addressed complaints about the fairness of the sales process."Train tickets sold online or by telephone have topped 2 million daily, meaning that around one-third of passengers don't have to wait in line at train stations for several hours to get a ticket," Hu said.However, many Chinese have expressed dissatisfaction with the website, with some people unable to get train tickets home for this year's Spring Festival holiday, a major holiday in China.Several customers posted their complaints on popular microblogging website weibo.com, stating that the booking site often failed due to "too many visits at the same time."The Spring Festival holiday is always a difficult time for China's public transportation authorities. A total of 3.16 billion passenger trips are expected during the holiday, up 9.1 percent from a year earlier, of which 235 million trips will be made via the country's railways, up 6.1 percent year-on-year, said Hu.This year's transport rush in the Spring Festival Season started on Sunday and will end on Feb. 16, according to the Ministry of Railways.

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BEIJING, Dec. 24 (Xinhua) -- A senior Chinese official has urged to improve work in the country's judicial administrative departments.Zhou Yongkang, a member of the Standing Committee of the Political Bureau of the CPC Central Committee, made the remarks at a meeting honoring excellent individuals and collectives in the judicial administrative sector in the past five years.Zhou commended the contributions that the judicial administrative departments have made to social stability, the building of socialist legal system, and the development of the society and economy, asking those being honored to make persistent efforts to serve the people.Zhou urged the judicial administrative organs at all levels to make new progress in serving the development by enhancing law awareness and providing high quality legal services.He also called for building grassroots mediation organizations that people can rely on, in order to resolve disputes in the grassroots and nip them in the bud.Labor education and rehabilitation in jails, as well as the community rehabilitation programs that can help law offenders successfully return and reintegrate into society, should be further improved, Zhou said, adding that it will also help enhance the social harmony by preventing repeated crimes.

  

BEIJING, Sept. 30 (Xinhuanet) -- China's space dream took a step closer to reality as the Tiangong-1 module blasted off into the night sky on Thursday from the Gobi Desert.The Long March II-F T1 rocket, under the unmanned module, Tiangong-1, lifted off from the Jiuquan Satellite Launch Center at 9:16 pm as planned.Ten minutes later Tiangong-1 separated from the rocket on its way to orbit, 350 kilometers above Earth. The module deployed its two solar panels, which provide power, at 9:28 pm.At 9:39 pm, Chang Wanquan, chief commander of the manned space program, declared the launch a success as cheers and applause echoed around the command and control center in Beijing.President Hu Jintao and other members of the Standing Committee of the Political Bureau of the Communist Party of China Central Committee went to the center to witness the launch.Premier Wen Jiabao watched at the Jiuquan Satellite Launch Center as the Long March rocket, carrying the space lab, blazed into the night sky.The launch paves the way for China's first rendezvous and docking mission. An unmanned Shenzhou VIII spaceship will be launched in November to dock with Tiangong-1.Two more missions are scheduled for next year and astronauts will board Tiangong-1, which can also function as a space lab.If the mission succeeds, China will become the third country to master spacecraft rendezvous and docking technology following the then Soviet Union and the United States, experts said.Wu Ping, the space program's spokeswoman, said that the ability to rendezvous and dock is vital for building a space station, which China has scheduled for around 2020."A space station cannot be launched in one shot. The modules must be launched separately and then assembled in space," she said.China has invested 35 billion yuan (.47 billion) in total on its manned space program since 1992, when it was approved, she told China Daily.The first phase, from 1992 to 2005, accounted for 20 billion yuan. During this period, China launched six Shenzhou spaceships to set up a system transporting astronauts between Earth and space.In the second phase, from 2005, 15 billion yuan has been spent on projects, including Shenzhou VII and the first rendezvous and docking mission, she explained.Zhou Jianping, chief designer of China's manned space program, said that the space lab and future space station provide a rare platform for conducting experiments that could lead to breakthroughs in the study of materials and biological pharmacy."Experiments made in the microgravity of space can lead to unexpected results," he said.For example, gas and liquid are unable to mix on Earth, but in space they mix naturally, he said."The primary purpose of China's manned space station is to peacefully explore space, and through it, serve mankind," he said.Some have questioned the participation of the military in the program. However, the military has experience in coordinating large-scale requirements that are vital for the program and their involvement reflects international norms, Ministry of National Defense spokesman Geng Yansheng said on Wednesday.He reiterated that China is firmly opposed to the weaponization of space and the program is peaceful.China is now in the second phase of its manned space program. The goal of the program, which has three steps, is to build a 60-ton space station around 2020.The second phase focuses on mastering four key technologies for assembling a space station.The first of these, extravehicular activity, was completed successfully in 2008 after Shenzhou VII was launched.Rendezvous and docking is what is being experimented with. The third technology involves cargo spaceships ferrying supplies to a space lab. The fourth tackles problems concerning the prolonged sustaining of life on a space lab, especially recycling air and water.Besides the manned space program, China launched two lunar orbiters in 2007 and 2010. It plans an unmanned lunar landing around 2013, and returning moon samples in 2017.

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