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The pandemic has raised awareness about convalescent plasma donation to treat coronavirus patients. But for hundreds of thousands of people who rely on regular plasma infusions to survive, a looming shortage is raising alarm bells.Mother, wife and rare disease advocate Deborah Vick lives with myasthenia gravis, a neuromuscular disorder that disrupts nerve to muscle communication.“The messages are no longer being able to reach the muscles to make them work--whether that is to walk or move or swallow or breathe--it's all interconnected,” described Vick.There is no cure, so every two weeks, she requires plasma infusions.“Being in crisis is the worst time to have to wait for treatment,” she explained. “I know, for me, my treatments are every two weeks and days before my treatment starts, my breathing is extremely labored.”Many types of primary immunodeficiency disorders like Vick’s result in an inability to produce antibodies or immunoglobulin to fight off infection.“There's about 250,000 of us in the United States alone,” said John Boyle, president and CEO of the Immune Deficiency Foundation.Canceled drives and fear of COVID-19 exposure, he says, have contributed to a drop in plasma donations for non-COVID therapy.This comes as the Red Cross says hospital distributions of convalescent plasma have increased 250 percent in November compared to September.“To not meet the rising demand is one thing, but to actually have less plasma is potentially very, very, very problematic,” said Boyle.Experts say it takes seven to 12 months to turn around plasma for patient infusion therapies. We are now nine months into the pandemic and a crisis say some could be around the corner.“There is a growing concern about the ability to meet patient clinical need,” said Amy Enfantis, president and CEO of the Plasma Protein Therapeutics Association.She says while the call for convalescent plasma therapies for COVID-19 has raised awareness, there is still an increased need for other rare-disease patients.“Our companies are making therapies every day for patients who have a perpetual need for plasma,” said Enfantis. “And that is ongoing regardless of a pandemic.”For those who rely on plasma donation and infusion treatment like Vick, it could mean the difference between life and death.“The biggest fear is not having the treatments that keep me alive. I mean, reality is I don't know what kind of life I will have, if any, how it will function without my infusions.”It’s why so many are hoping those who can, will give. 2536

The Postal Service says it is facing “historic volumes” going into its busiest shipping week of the year. While Tuesday marks the final day the Post Office recommends shipping packages via ground in time for Christmas, the USPS says there are still a number of options for customers hoping to get their packages to loved ones by Dec. 25.In an effort to assist customers, the USPS says it is enacting a number of measures in hopes of ensuring timely deliveries.Those measures include:Expanded holiday retail hours in select locationsExpanded package delivery window — delivery in morning, afternoon, and early evening where volume warrantsExpanded operational capacity with new equipmentLease extra vehicles as needed to expedite deliveriesFor customers in the continental US, the USPS recommends the following mailing and shipping deadlines for expected delivery by Dec. 25 to most US addresses.Dec. 15 — USPS Retail Ground serviceDec. 18 — APO/FPO/DPO (except ZIP Code 093) USPS Priority Mail Express serviceDec. 18 — First-Class Mail service (including greeting cards)Dec. 18 — First-class packages (up to 15.99 ounces)Dec. 19 — Priority Mail serviceDec. 23 — Priority Mail Express serviceUSPS notes that only the Priority Mail Express service is a guarantee, and the other deadlines are merely recommendations. “We thank our customers for their continued support, and we are committed to making sure gifts and cards are delivered on time to celebrate the holidays,” said Kristin Seaver, Chief Retail and Delivery Officer of the Postal Service. “We also thank our 644,000 employees who are working tirelessly throughout these unique conditions to ensure the delivery of holiday gifts and greetings."Heading into the holidays, USPS service reported significant slowdowns. For the months of July, August and September, USPS reported single-piece first-class mail fell below its annual benchmarks, and past performance. During the quarter, three-to-five day on-time service dropped from 87.8% in 2019 to 72.1% in 2020. Its two-day on-time service dropped from 94% to 88.2% from 2019 to 2020. 2099

The makers of the popular video game Fortnite have a big supporter in their corner as they go to battle against Apple - Microsoft.A few weeks ago, Epic Games introduced Epic Direct payments, a direct-payment plan for Apple's iOS and Google Play that bypasses the App Store.Apple said the service violated its guidelines, so they removed the game from the App Store.Epic, in return, took legal action. On Sunday, Microsoft issued a statement, which was tweeted out by Xbox boss Phil Spencer, that explained they were backing up Epic in their court battle because "Apple’s discontinuation of Epic’s ability to develop and support Unreal Engine for iOS or macOS will harm game creators and gamers." 703

The Portland (Oregon) Police Department said that 49 people were arrested stemming from what the police called “riots” in Oregon's largest city over the weekend.Sunday marked the 74th day of unrest in Portland following the Memorial Day death of George Floyd who died while in Minneapolis Police custody. The period of unrest included federal agents engaging with protesters at the city’s federal courthouse, which prompted nationwide scrutiny over the use of federal officers for domestic law enforcement purposes.Among the demonstrators arrested over the weekend was Demetria Hester, a prominent Black Lives Matter activist who leads the group Mothers United for Black Lives Matter. The 46-year-old demonstrator was arrested Sunday on charges of disorderly conduct and interfering with a peace officer.Hester testified in a hate crime case earlier this year against a man involved in a sentenced train attack, saying that she had been attacked by self-described white nationalist Jeremy Christian before the deadly incident. Christian wound up be sentenced to life in prison after being found guilty of killing two people in a hate crime.Friday night marked the most arrests from the weekend, 24, and the injury of an Oregon State Police Trooper, who police said was wounded from being struck in the head by a rock.The department said that there were two separate gatherings in the city on Friday. The first, the police say, was a peaceful demonstration that officers did not interact with. But a second gathering nearby, the department said, began to turn violent.On Saturday, a second protest took place and lasted peacefully for four hours, according to police. But tensions began to rise after the group marched, and vehicles began to illegally block intersections.Some in the crowd then set fire to Portland’s police union building, prompting the department’s officers to engage with the crowd.“People within the crowd committed crimes when they erected a fence, pushed dumpsters into the street to block traffic, set a dumpster on fire, vandalized the PPA office with spray paint, and destroyed security cameras,” the Portland Police said. “At 11:35 p.m., people within the crowd broke the window to the PPA Office, unlawfully entered, and started a fire, committing the crimes of criminal mischief, burglary, and attempted arson.”On Sunday, an additional 16 arrests were conducted as two Portland officers were injured by a mortar. 2448

The man convicted of killing his pregnant wife and two young daughters in Colorado is likely now in the Wisconsin Department of Corrections. According to media reports, including Radar Online, Chris Watts, 33, was transferred to Dodge County Correctional Institution last week. Watts eventually confessed to killing his pregnant wife and two young daughters in August. He took a plea deal to avoid the death penalty. He was sentenced to five life sentences. The Wisconsin Department of Corrections would not confirm whether Watts is in its custody but released the following statement: "The Department of Corrections is not confirming the location or disclosing the identity of inmates who may have been transferred to Wisconsin under the Interstate Corrections Compact. Questions should be referred to the state correctional agency which transferred the inmate."On the Wisconsin Department of Corrections website, there is a link to send money to inmates. A Chris Watts, with the same date of birth, is listed on the Wisconsin DOC commissary listing. The site only lists Watts as being in the Wisconsin DOC, however, Radar Online says he is specifically being held at the Dodge County Correctional Institution.Dodge County Correctional Institution is the same prison where other notorious killers like Ed Gein, the man who inspired the movie Psycho, have been held. "I'm not able to confirm any information regarding the possible location of inmate Christopher Watts," a Dodge County Correctional Institution spokesperson said.According to the Colorado Department of Corrections, high-profile prisoners can be moved to another state's system for safety reasons under the Interstate Compact. These moves are not always permanent.  1778