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SAN DIEGO (KGTV) -- If you are experiencing mental fatigue like never before, you are not alone. Many people who are used to forging ahead in times of crisis, like this coronavirus pandemic, say the feeling is unfamiliar. Emily Chandler of Vista says she never could have imagined her kids would still be distance learning in the fall. "This has been going on so long, and I'm just exhausted," Chandler says. Her three sons are in three different schools and her oldest, Timmy, has autism. Helping them all with school means studying up on things herself. Marriage and family therapist Serene Carruthers, of Sharp Mesa Vista Hospital, says what Chandler is feeling is tied to the seemingly endless nature of the pandemic."It really is because our body is built to respond to stressful events typically that last for a duration of a short period of time," says Carruthers. "Some experts call it surge capacity. Like a battery our adaptive system can provide us with the mental, physical and emotional power to survive a short-term emergency. Then it needs to be recharged which is easier said than done during a pandemic because for many people, their self-care rituals have been upended or canceled.""It is a very lonely time and I'm not getting that energy, that recharge," says Chandler. Carruthers says not to underestimate the power of play, which is free and can be done anywhere. She also recommends shifting expectations, maintaining connections with loved ones, keeping a gratitude journal about the good in your life, and exercising even if it's just walking in your home. Chandler says the reopening of her gym helped her feel like herself again, and she and Carruthers both say it's all right to ask for help, which Chandler says she's glad she did."I got on an anti-anxiety medication and I'm not embarrassed about that. It's really, really helped me," Chandler says.What has also helped is her boys have been troopers, making it clear that sometimes the biggest challenge can also bring the greatest joy. 2031

SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) — Maritime Museum of San Diego will reopen to the public on Aug. 22, with new precautions for visitors and limited capacity.Museum officials say they have placed 6-foot markers on the upper decks of ships to remind visitors to practice social distancing while visiting. Capacity for the museum has also been cut to 25%, but staff will monitor levels every 15 minutes.Guests and staff will undergo temperature checks and wellness screenings before entering the museum, and facial coverings will be required. The museum is also condensing its hours to 10 a.m. to 5 p.m.Due to the high touch potential, the museum's gift shop is temporarily closed. Museum staff will be cleaning and sanitizing surfaces throughout the day.The museum's tours will be self-guided, but volunteers will be available through the museum to help guests."We wanted to offer a special treat for visitors and residents of San Diego during the stress of the global pandemic," Raymond Ashley, president and CEO of the Maritime Museum of San Diego, said. "So, a stroll aboard the decks of these historic ships and refreshing, educational boat ride in San Diego Bay could be the perfect break.The museum will offer outdoor activities, such as self-guided tours, of the museum's fleet of historic vessels. Guests will be able to make reservations for Harbor History Bay tours for an additional charge with admission as four, 45-minute narrated tours daily at 12:30 p.m., 1:30 p.m., 2:30 p.m., and 3:30 p.m.Bay Boat tour reservations are also available.General admission tickets for adults cost , and for seniors 62+, military and ages 13-17. Children 12 and under can visit for . Cash will not be accepted for tickets purchased in person.The Maritime Museum reopened from July 1 to July 6, after being closed since March due to the pandemic, but was closed once again when California barred indoor operations. 1909

SAN DIEGO (KGTV) - Less than a week before the election, there are reports of political yard signs being stolen and vandalized, and in some cases, appearing in yards.Sunday night, just before midnight in a cul-de-sac in El Cajon, surveillance video shows a car driving slowly before it stops to let someone out."A shadowy figure, looks young, maybe 10 years old, gets out of the vehicle, runs in, and grabs a political sign," said Brandon Spaulding.Spaulding says the sign being taken belonged to his neighbor and it read "Trump/Pence, Make America Great Again." That same night, Spaulding's sign, which had been vandalized days before, also disappeared.The apparent thieves in the Sunday's thefts: a child and an adult."Very disappointed and frustrated ... being a terrible role model. As parents, you’re supposed to teach children the different between right and wrong. I was always taught to love my country, and part of that is freedom of speech. Respect people's rights to say what they want to say," said Spaulding.Spaulding isn't alone. Local Republican Party officials say they've received more than a 100 reports of stolen Trump signs, a greater number when compared to previous presidential elections.In Coronado, police responded Wednesday to seven homes, where yard signs reading "Racism Lives Here" appeared in front of the homes of Trump supporters who were displaying signs or flags.It isn't just Trump backers being targeted. On the Nextdoor mobile app, ABC 10News found numerous examples of signs supporting presidential challenger Joe Biden stolen.Just south of Balboa Ave., Margo Thomas woke up Wednesday to her Biden/Harris yard sign gone."To me, it just feels like you’re stifling free speech," said Thomas.There is still no mistaking who Thomas is backing. A "California for Biden" sign still stands in her yard.In El Cajon, Spaudling immediately purchased new Trump signs for his yard and for two neighbors.ABC 10News reached out to the local Democratic Party officials for theft numbers and are waiting to hear back.Campaign sign theft does qualify as misdemeanor petty theft, which carries with it a maximum penalty of six months in jail. 2171

SAN DIEGO (KGTV) — Local research organizations and San Diego County are teaming with the CDC to expand the genome sequencing of COVID-19. That data gives county leaders important information to drive decision-making to help slow and control the spread of the virus.“The virus is constantly evolving and trying to figure out the best way to spread through our population. And is it does that, it changes a little bit,” said Dr. Louise Laurent a professor at UC San Diego, which is part of the team, along with Scripps Research.Laurent says that studying changes in the virus can help identify which cases are connected to each other and which are not. The county can use that information to understand what measures are working, where there are significant outbreaks, and whether new measures are needed to stop those outbreaks.The county’s top epidemiologist, Dr. Eric McDonald, tells ABC 10News that the data shows that through testing and contract tracing, efforts to control outbreaks have generally been effective. “It looks like many of the instances of individuals who are infected don’t result in too many other infections. We don’t have lots of big clusters of the same exact strain,” McDonald said.The data also shows that while the restrictions and actions taken by the county have been effective in controlling outbreaks, COVID-19 continues to spread in San Diego through travel. “What we found is that San Diego has been hit many different times and viruses from other places have come to San Diego,” Laurent said. “We don’t want to be an isolated place. We want to interact, right? We’re just that kind of place. It makes us vibrant. It makes us an interesting place to be. But that also makes us vulnerable.”The research team recently received a .5 million contract from the CDC to expand its work. 1823

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