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发布时间: 2025-05-30 23:51:40北京青年报社官方账号
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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

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CAIRO, July 4 (Xinhua) -- U.S. and Italian archeologists have discovered the oldest description about an Egyptian king (about 3, 200 BC) in Egypt's Aswan, Egyptian Antiquities Minister Zahi Hawass said on Monday.The engravings "traces back to when the Egyptian language firstly recorded in hieroglyphs and tells about a unique complete royal ceremony which was known in the ancient Egyptian era," said Hawass in a statement."The pharaoh appears to be wearing the Upper Egypt crown accompanied by (Horus apostles) at the royal court, " Hawass added.Horus is one of the oldest and most significant deities in the ancient Egyptian religion and was worshipped from at least the late Predynastic period through to Greco-Roman times."This discovery is considered a supplementary one at the site unearthed near in el-Hamdulab site in northern Aswan, archaeologists said.This is one of the latest discoveries in Egypt as the surrounding wall of Betah temple (1550 BC-1070 BC) and a gate traces back to Shabaka king era were unearthed on Saturday in Luxor.

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PARIS, Sept. 21 (Xinhua) -- European heavy-lift launcher Ariane 5 lifted off two communication satellites Wednesday from the Kourou launch centre in French Guiana, live broadcast of the launching process showed.The rocket, carrying the two communication satellites Arabsat 5C and SES-2, was launched at GMT 2138.This was the fifth heavy-lift mission of Ariane 5 in 2011. Arianespace had planned six Ariane 5 missions through 2011.The satellite Arabsat-5C was developed for the Arab Satellite Communications Organization (Arabsat) to provide satellite capacity in both C-band and Ka-band frequencies for a wide range of communications services.Jointly produced by Europe's EADS Astrium and Thales Alenia Space, it will be positioned at 20 degree East orbital location to cover the Middle East and Africa.Manufactured by Orbital Sciences Corporation of the United States, SES-2 will join the fleet of European satellite telecommunications operator SES, and is to be positioned at 87 degree West for coverage over North America and the Caribbean.Both Arabsat-5C and SES-2 have life-spans as long as 15 years.This Ariane 5 dual-passenger mission was postponed from Tuesday due to local strikes of French Guiana workers.Founded in 1980 as the world's first launch service and solutions company, Arianespace planned to achieve six Ariane 5 missions through 2011. Through 2010, heavy-lift workhorse Ariane 5 finished six missions, sending a dozen spacecraft into expected orbits.The next mission from Arianespace centre in Kourou was scheduled for Oct. 20 by medium-lift vehicle Soyuz. It will be Soyuz' first mission from French Guiana with a pair of satellites for Europe's Galileo satellite navigation system.

  

THE HAGUE, Aug. 16 (Xinhua) -- ESBL-enzymes, which are known for their ability to stop the effects of antibiotics, can directly pass from chicken to people, said a research published on Tuesday.Veterinary researcher Dik Mevius of the Wageningen University released the finding in the magazine Resource.The research group led by Mevius has isolated six ESBL-genes varieties and compared them to bacteria found on hospital patients, on super market poultry and in laying batteries. In 35 percent of all cases, they discovered a match of 100 percent.Bacteria like Klebsiella on E. coli can produce the ESBL-enzymes. A healthy person will not feel any effect, but people with a lower immune system can get very sick. In areas like a hospital, the infection can easily spread."The main concern is that the enzyme resists the most used antibiotics, which makes the treatment of infected persons difficult," said Mevius.According to Mevius, 94 percent of supermarket poultry carries the enzyme, but all enzymes will be killed during the heating process of cooking.

  

KATHMANDU, Aug. 7 (Xinhua) -- Ban on smoking in public places will be enforced from Sunday with the Tobacco Control and Regulatory Act-2010 coming into effect.Those smoking in public places will be fined and civil servants will be liable to departmental action.Government offices, corporations, educational institutions, libraries, airports, public vehicles, orphanages, childcare centres, cinema halls, homes for the elderly, cultural centres, children's gardens, hotels, restaurants, resorts, girls' and boys' hostels, department stores, religious sites and industries have been designated no-smoking zones.Health Secretary Sudha Sharma said mass awareness campaign highlighting punishment will be carried out. She also said an inter-ministerial coordinating committee has been formed to enforce the law to ensure people's right to health. Pasting no- smoking notices at every public place will be mandatory.According to The Himalayan Times daily, the ban covers sale of tobacco products and single sticks within a 100-meter radius of educational and health institutions, children's homes, child care centers and home for elders.Anyone selling tobacco products to persons under the age of 18 years and pregnant women will be fined.The Act also prohibits advertising and sponsoring programs in the name of tobacco-related products through media. Offenders will be fined.The government's mass awareness campaign will cover the entire country to ensure effective implementation of the Act.

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