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SAN DIEGO (KGTV) — The alarm blares in your ears, as your eye lids slowly peak open and usher in a flood of sunlight. You drag your feet along the floor to the kitchen, where a device that has saved mornings for so many awaits you.Coffee is often regarded as a necessity to begin the day, but sometimes it's just what the doctor ordered for a relaxing day. In San Diego, several local coffee roasters and houses blend together their unique coffee recipes that can both kickstart your day or provide a warm moment of solace.And as National Coffee Day comes on Sept. 29 this year — a Sunday — there's no better time to wake and relax at a coffee house before the work week kicks into gear. While you're out and about, be sure to duck into one of San Diego's many coffee houses to sample their invigorating drinks:Bird Rock Coffee Roasters (Locations in La Jolla, Bressi Ranch, Little Italy, Torrey Pines, Morena, Pacific Beach): Bird Rock boasts high-quality coffee, their own signature mixes, and seasonal blends of delicious coffees at their locations around town.Better Buzz (Locations in La Jolla, Pacific Beach, Hillcrest, Encinitas, Fashion Valley, Point Loma, Mission Beach, San Marcos): In addition to their signature drinks like "Best Drink Ever" and "Hazelnut Divinity," Better Buzz offers delicious cold brews, mochas and lattes, and eats to match.Dark Horse Coffee Roasters (Locations in Normal Heights, North Park, Golden Hill, La Mesa): Head over to Dark Horse Coffee Roasters for their signature Espresso drinks, like “The Champ” or cold brew on nitro with a splash of vanilla bean syrup.Lofty Coffee & Bakery (Locations in Solana Beach, Encinitas, Little Italy): Lofty Coffee roasts its own beans and crafts pastries from scratch at hubs along San Diego's coastal communities.Jennings House Cafe: One of San Diego's oldest coffee brands, Jennings House Cafe serves up Cura Coffee and delicious breakfast dishes in a historic landmark home dating back to 1886.The WestBean Coffee Roasters (Locations in downtown, Liberty Station, Bankers Hill): WestBean sources its own beans, churning out some delicious espressos and refreshing cold brews.James Coffee Co. (Locations in Little Italy, Bankers Hill, downtown, Columbia): James Coffee Co. puts together your traditional brews plus some delicious specialty drinks with honey cinnamon, Mexican mocha, or coffee soda.Philz Coffee (Locations in La Jolla, Del Mar, Encinitas): The Bay Area brings specialty beans — 28 types of beans, in fact — involving a variety of flavors like grapefruit, Cherry, maple, and others.Refill: Refill packs its java house with all the needed brews: Mochas, lattes, cappuccinos, and some delicious cold brew concoctions and crepes.Modern Times: In Modern Times' Lomaland Fermentorium, the brewery roasts its own beans in a modest roaster beside taps of its brews. And of course, so of those beans have crossed over to combine barrel-aged beans.Heartwork: San Diegans have long been fans of Heartwork's brews using James Coffee Co. and Dark Horse roasted beans.Moniker Coffee Co.: A variety of small-batch coffee from local producers and some out-of-town roasters can be found at Moniker's Liberty Station stop.Communal Coffee (Locations in South Park, North Park): Grab a cup of coffee and flowers on the side! Communal Coffee, which serves Sightglass Coffee from San Francisco. Expect some creative drinks like rose vanilla, taro, and sea salt and caramel coffees.Revolution Roasters (Location in Oceanside): Fresh-baked pasteries, breakfast dishes, and of course, an awakening variety of coffees awaits at Revolution Roasters, including their signature Lavender Honey and Butterscotch lattes.SkyBound Coffee + Dessert Lounge (Locations in Vista, Downtown San Diego): Whether you want your coffee hot or cold, SkyBound has what you need with their Skybound Dark Chocolate Mocha, iced lavender vanilla, sea salt, or VanillaCali coffees.Perks Coffee House (Location in San Marcos): Delicious cold brew on tap, freshly roasted beans, and a variety of Espresso drinks will surely perk your senses at Perks Coffee House. Keep an eye on their seasonal Cafe Viennese, Dirty Chai latte or go for something a little harder like Irish Coffee. 4234

SAN DIEGO (KGTV) — The County Board of Supervisors voted Tuesday to send a letter to Gov. Gavin Newsom requesting they be allowed to reopen the local economy.The board voted 4-1, with Supervisor Nathan Fletcher voting "no," to take further steps into reopening amid the coronavirus pandemic. The letter requests San Diego County be permitted to reopen gyms, hotels, nail salons, wineries and breweries, churches at full capacity, theme parks, youth sports, charter and fishing boats, community pools, and museums, Supervisor Jim Desmond tweeted.Following the vote, Desmond said in a statement that it will be up to Newsom, but that most of the board believes the county is ready.RELATED: Passive recreation activities now allowed at San Diego County beaches"Just now, the Board approved a plan telling the Governor we are ready to open for business. It's ultimately up to the Governor to decide, but the message is clear from the Board of Supervisors, we are ready to open," Desmond's statement read.It wasn't immediately clear what specific limits these businesses would be required to operate under if allowed to reopen. Though, the county has released reopening criteria (available here).Fletcher said he could not support the measure to send the letter to the state because he believes "we should stay the course in opening in a safe, responsible and systematic way."RELATED: San Diego County allows churches to reopen with limits"We have had success in our re-opening because of the approach we have taken and not in spite of it. While I agree with the need to continue our safe reopening, and believe a number of additional entities are ready to open at this time I could not support the calls by my colleagues to reopen higher risk entities like churches at full capacity immediately," Fletcher wrote. "I look forward to additional progress in the coming days and weeks but do not support this reckless approach."The board also voted to immediately reopen all beach activities and requested a staff report on how COVID-19 has impacted San Diego's most vulnerable populations.As of Tuesday, San Diego County reported 7,554 coronavirus cases and 269 deaths. 2170

SAN DIEGO (KGTV) - The Downtown Central Courthouse plans to resume jury trials in two weeks after a six-month postponement during the shutdown, but there are concerns about the massive backlog of cases and keeping jurors safe. Non-jury trials are currently in progress through a remote virtual process.“I do have an incredible backlog, not only in criminal but also in civil cases,” said San Diego Superior Court Presiding Judge Lorna Alksne on Monday. So far, 900 jury duty summonses have been sent out for telephonic standby for in-person appearances in groups of 70 people. “The jury lounge [holds] 500 to 600 people but instead of that were going to bring in 70 [people and] socially distance them,” she added.Those people who are selected for jury will sit in courtrooms which have been retrofitted with protective measures like plexiglass barriers. Judge Alksne said there around about 2,400 criminal cases ready for trial that must be reset. Beyond that, there are thousands of other criminal proceedings to get to. “There's about 17,000 other things that need to be reset before they can even get to a trial,” she added.Civil cases are another obstacle. A spokesperson for the Courthouse confirmed that there are approximately 54,000 civil cases that are pending. There are about 2,800 that are ready to go to trial but Judge Alksne said Monday that civil jury trials likely won't resume until sometime in 2021.“The only way that I'm going to beat this backlog is if jurors come in for jury service so if you feel like you're able to serve, we would ask you to respond to the summons and come into court and help us get the jury trials started again,” she added.She noted that civil bench trials will start in mid-October and in-person arraignments will start on November 1st. 1792

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) - The future of warfare is in San Diego for the time being. The 21st Century Combined Arms Advanced Naval Technology Exercise is currently taking place at the Naval Information Warfare Center Pacific (NIWC Pacific). ANTX West 2019 is roughly two weeks long and features the brightest in the military, academia and industry demoing the latest advancements to see if they are ready for the battlefield. “This isn’t a trade show - this is ‘get people together let’s go do things and see how it goes,’” said Rear Admiral Donald Gabrielson, “this is innovation.” Much of technology of the the last several years has focused on human and machine interactions with virtual reality. “We can give feedback to the industry and say this is eligible for rapid prototyping or this needs some science and technology investment,” said Richard Byers, a systems engineer with the Navy. More than 80 developing products and systems are being tested at NIWC Pacific along with San Clemente island. “Being able to apply the technology in an operational a realistic environment is critically important,” said Brigadier General Christian Wortman, USMC.Congress has given the military the power to fast track products that perform well at ANTX for rapid prototyping and their discretion. 1290