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KUNMING, Nov. 30 (Xinhua) -- More than 10,000 new HIV infections were reported in southwest China's Yunnan province during the first 10 months of this year, bringing the total number of HIV carriers and AIDS patients in the province to more than 90,000, local AIDS prevention authorities said Wednesday.As of Oct. 31, a total of 93,567 HIV infections had been reported in the province, with the disease claiming 14,340 lives, according to statistics from the Yunnan AIDS Prevention Bureau.The number of HIV infections contracted through sexual contact has been rising and sexual contact is now the main cause of the disease's proliferation, said Xu Heping, director of the bureau.Of the province's infected population, 45.8 percent contracted the disease through sexual contact, while 37.3 percent contracted the disease through intravenous drug abuse, according to the bureau.Sexually transmitted infections accounted for 77.3 percent of new infections during the January-October period, up from 71.3 percent during the same period last year, according to the statistics.Xu said this year's new infections mainly occurred in people between the ages of 20 and 39, accounting for 60.8 percent of the total.Infections among rural residents and unemployed people accounted for 55.3 percent and 18.6 percent, respectively, of this year's total, according to Xu.Lu Lin, director of the Yunnan disease control and prevention center, said migrant workers are particularly vulnerable to the disease due to their nomadic nature and lack of knowledge about the disease.China currently has 346,000 registered HIV carriers and AIDS patients, although the actual number is predicted to hit 780,000 by the end of this year, according to an expert panel consisting of members of China's Ministry of Health (MOH), the World Health Organization and UNAIDS.

SAN FRANCISCO, Dec. 15 (Xinhua) -- Microsoft on Thursday announced that it will automatically upgrade the Internet Explorer (IE) to the latest version to give Windows customers more protection against malicious software.According to the company's blog post, starting from Australia and Brazil next January, users of Windows XP, Vista and Windows 7 will get the IE updates if they have turned on automatic updating via Windows Update.Microsoft said the industry has been moving toward automatic updates as a norm since the biggest online threat these days is social engineering malware typically targeting outdated software like Web browsers.Automatic upgrades, also called silent updates for displaying no messages or windows during the progress, has been deployed by Google's Chrome and Mozilla's Firefox. It can ensure users have the newest versions of the browser, and therefore is seen as a big improvement to Internet security.According to the Microsoft Security Intelligence Report released in October, 99 percent of all attacks during the first half of 2011 came from unpatched but known vulnerabilities, and 90 percent of infections were attributed to vulnerability exploitation that had a security update available from the software vendor for more than a year.In the latest research data from Web analytics company StatCounter, Microsoft's IE has a strong lead with 40.63 percent of global browser market share, followed by 25.7 percent of Chrome and 25.23 percent of Firefox.
WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."
CANBERRA, Oct. 15 (Xinhua) -- Prisoners and health experts on Saturday told national broadcasting network ABC News that they are concerned of a looming HIV epidemic in Australia's prisons.The warning came following a test report undertaken in August showed that 40 percent of inmates at a correctional center in Canberra of Australia tested positive to Hepatitis C.According to the head of the Alcohol and Drug Service based at St Vincent's Hospital in Sydney, Alex Wodak, roughly 25 percent of Australia's prison population are injecting drugs, and he is concerned about the risk of an HIV explosion in Australia originating in prisons."Were Australia to have an epidemic of HIV beginning among people who inject drugs, it is almost certain that it would begin in one of our prisons. So we are very exposed to this risk," he told ABC News on Saturday.The Australia Capital Territory state government has proposed a trial prison needle exchange program in Canberra's correctional center, and Paul Cubitt, who currently works at the Alexander Maconochie Center in Canberra, said he has never seen so many syringes in a jail."Under a controlled regime it will actually take those needles that currently exist within a correctional center out of the environment, and prisoners will be more willing to use a clean item under a level of anonymity which then protects them and protects staff," he said.Meanwhile, The Community and Public Sector Union 's national secretary, Nadine Flood, agrees action must be taken to curb prisoner drug use.Dr Wodak noted that prison needle exchange programs have been operating overseas for over a decade with ten countries provide inmates with clean needles, and said it is shameful Australian prisons are lagging behind.
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