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SAN DIEGO (CNS) - An international team of scientists, led by biologists at the University of California San Diego, has synthetically engineered mosquitoes that halt the transmission of the dengue virus, the university announced Thursday.Scientists at UC San Diego Associate Professor Omar Akbari's lab worked with Vanderbilt University Medical Center to identify a human antibody for dengue suppression. The broad-spectrum antibody stops the transmission of all four known types of the fever, compared to previous experiments, which have been able to limit single strains.The team then designed the antibody "cargo" to be synthetically expressed in the dengue-spreading Aedes aegypti mosquitoes.RELATED: UC San Diego study finds solutions for loneliness"Once the female mosquito takes in blood, the antibody is activated and expressed -- that's the trigger," Akbari said. "The antibody is able to hinder the replication of the virus and prevent its dissemination throughout the mosquito, which then prevents its transmission to humans. It's a powerful approach."Akbari works in the Division of Biological Sciences and is a member of the Tata Institute for Genetics and Society.These lab-engineers mosquitoes could be paired with a dissemination system, making it capable of spreading the antibody throughout wild disease- transmitting mosquitoes, Akbari said.Dengue fever is a virus that poses a severe risk to children and older adults in tropical regions in Asia and Latin America. There are an estimated 390 million infections every year, around 500,000 of which lead to Severe Dengue, and 25,000 people die of the disease every year.RELATED: UCSD Health, San Diego Zoo Safari Park team up to save gorilla's eyesightThe Pan American Health Organization recently reported the highest number of dengue cases ever recorded in the Americas. Infecting those with compromised immune systems, dengue victims suffer flu-like symptoms, including severe fevers and rashes. Serious cases can include life-threatening bleeding. No specific treatment exists and thus, prevention and control depend on measures that stop the spread of the virus.This development could go a long way toward limiting the disease's transmission."It is fascinating that we now can transfer genes from the human immune system to confer immunity to mosquitoes," said coauthor of the paper, Dr. James Crowe, Jr., director of the Vanderbilt Vaccine Center at Vanderbilt University Medical Center in Nashville, Tenn. "This work opens up a whole new field of biotechnology possibilities to interrupt mosquito-borne diseases of man."Akbari's lab is now in the early stages of testing methods to simultaneously neutralize mosquitoes against dengue and a suite of other viruses such as Zika, yellow fever and chikungunya. 2789

SAN DIEGO (CNS) - Monday is the deadline for San Diego County residents to register to vote in the Nov. 3 election.County residents will need to register or re-register to vote if they are not registered in San Diego County, recently moved or changed their name.County residents can check their registration status online at sdvote.com.If they are not registered or need to change their registration, they will be able to complete an online registration form.If their signature is confirmed through records at the Department of Motor Vehicles, it will automatically be sent to the Registrar of Voter's office.If a signature is not confirmed, the form can be printed out, signed and returned to the registrar's office at 5600 Overland Ave. in Kearny Mesa by 8 p.m. on Monday.Registration forms are also available at the offices of the U.S. Postal Service, City Clerk, public libraries and Department of Motor Vehicles.Election materials are also available in Spanish, Filipino, Vietnamese and Chinese.Registration forms must be postmarked or delivered to the Registrar of Voters office by 8 p.m. Monday. Voters may also register online until midnight.If you miss the deadline to register, you may still conditionally register and vote provisionally through Election Day.Early voting is underway at the registrar's office in Kearny Mesa. Voters can cast their ballots there Monday through Friday, 8 a.m. to 5 p.m.For more, visit www.sdvote.com. 1450

SAN DIEGO (CNS) - Initial results are expected in the next few days on previously untested rape evidence kits that will help identify offenders who may potentially be linked to other sexual assaults, San Diego County District Attorney Summer Stephan announced Tuesday.Earlier this year, the District Attorney's Office, working with the San Diego County Sheriff's Department, contracted with a private lab, Bode Cellmark Forensics in Lorton, Virginia, to test about 1,000 untested sexual assault kits. So far, 350 rape kits have been sent to the lab for testing, Stephan said.The county's top prosecutor said reducing the backlog of untested sexual assault kits has been a top priority of hers since she took office last July. With the support of San Diego County's chief administrative officer, officials identified about million to go toward the effort of expedited 877

SAN DIEGO (CNS) - Gov. Gavin Newsom announced Friday that the city of San Diego is one of four cities in the state that will receive 0,000 in state funding to support residents affected by power shutoffs due to the threat of wildfires.While visiting Sonoma County emergency responders, local officials and residents affected by the Kincade Fire, Newsom announced the establishment of the Local Government Public Safety Power Shutoffs Resiliency Program, which will provide funding to local governments to maintain power service to high- risk areas affected by power shutoffs.San Diego, Los Angeles, San Jose and Oakland will each receive 0,000 in state funding through the program and all 58 counties in the state will receive at least 0,000 each. An additional million will be made available through a competitive grant process for incorporated areas of the state and .5 million will be available for tribal governments.The state included million in one-time funding in the state's 2019 budget to maintain public safety and limit the effects of power shutoffs by companies like San Diego Gas & Electric and Pacific Gas & Electric. Half of that funding will go to local governments and half will fund state agencies and departments to continue providing public services in the state."We must do everything we can to support Californians, especially those most vulnerable to these events," Newsom said. "These funds will help local governments address these events and assist their most vulnerable residents."Newsom and other officials in the state have hammered public utility companies like SDG&E and PG&E for shutting off power for multiple days at a time to protect against potential wildfire danger. State investigators determined earlier this year that PG&E equipment in Butte County caused last year's Camp Fire, the most destructive fire in state history, which killed 85 people.Newsom wrote a letter earlier this week to SDG&E, PG&E and Edison International executives, calling on them to coordinate power shutoffs with state officials. He also called on PG&E to offer rebates to customers affected by the shutoffs 2180

SAN DIEGO (CNS) -- Hot temperatures are expected Tuesday throughout San Diego County amid a heat wave that will last through Thursday, according to the National Weather Service.High pressure will continue to strengthen through Thursday, causing the mercury to rise in most parts of the county, forecasters said. Temperatures will drop to around average when low pressure arrives on Friday.10News Meteorologist Megan Parry says temperatures are expected to near record highs in San Diego, Chula Vista, El Cajon, Oceanside, Carlsbad, Escondido, Poway, La Mesa, and Vista. Tuesday is set to be the hottest day of the year so far, according to Megan's forecast.RELATED: 10News Pinpoint Weather ForecastA heat advisory will be in effect Tuesday from 11 a.m. to 7 p.m. in coastal areas.Winds out of the east will be calmer than Monday, with wind speeds between 15-25 mph expected and gusts possibly reaching 40 mph.The NWS urged residents to drink plenty of fluids, stay out of the sun and check up on relatives and neighbors.Also, young children and pets should be never be left unattended in a vehicle, with car interiors able to "reach lethal temperatures in a matter of minutes," according to the NWS.High temperatures Tuesday are forecast to reach 91 degrees near the coast, 98 inland, 99 in the western valleys, 91 near the foothills, 86 in the mountains and 100 in the deserts.The mercury in coastal areas is expected to top out in the high-70s to low-80s near the coast and the mid-80s to low-90s inland on Wednesday, while temperatures in the western valleys are forecast to reach the low- to mid- 90s, forecasters said. 1631