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SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) - If you've been missing the unicorn and rainbow concoctions that swept across plates and Instagram pages this year, the San Diego County Fair will have you covered.The sparkly and colorful wave of foods will be featured at the Del Mar Fairgrounds this year, thanks in part to 2018's theme of "How Sweet It Is."Among some of the magical offerings are the cotton candy ice cream sandwich from Chicken Charlie's (a fair mainstay), TastiBurger's unicorn fries and unicorn burger, Bacon A-Fair's unicorn party pineapple, and unicorn dogs from Pink's Hot Dog.RELATED:  613

SAN DIEGO (KGTV) - In the wake of the coronavirus budget crisis, cuts are being proposed to child welfare services.The proposed cuts come just weeks after Gov. Gavin Newsom announced new investments totaling million to protect younger Californians at heightened risk for abuse and mistreatment due to COVID-19.The April announcement directed funding to support families struggling to stay together, additional social worker outreach, family resources centers, and age extension for foster youth, among other things.According to the County of San Diego, "The funds approved by Governor Newsom will be used in part, as earmarked, benefiting Child Welfare families receiving emergency response and family maintenance services. The County of San Diego Health and Human Services Agency, Child Welfare Services is partnering with the state as it seeks to provide 0 monthly payments to families with children who are at risk of entering foster care. In addition, funds were allocated to help youth who have exited out of the Child Welfare System. The funds will allow foster youth who turn 21 to extend their stay in foster care to prevent potential homelessness during the COVID-19 pandemic. San Diego is receiving 0,000 in Transitional Housing Program funds from SB80 which will be used to reduce youth homelessness through the expansion of transitional housing so that we can support youth exiting foster care even after the funds provided for COVID response are no longer available. Funds are also allocated for youth to get access to cell phones and laptops through the iFoster program to continue to participate in educational activities and stay connected with their families during COVID-19. iFoster and San Diego County Child Welfare Services have been working together since 2013 to provide resources to children, youth and caregivers. CWS began working with iFoster to provide cell phones to foster youth in 2019 and will continue this partnership. "But that money will only last so long. The governor's May budget revise contains cuts to children's programs.The budget states: "Child Welfare Services include family support and maltreatment prevention services, child protective services, foster care services, and permanency programs. California's child welfare system provides a continuum of services for children who are either at risk of or have suffered, abuse, neglect, or exploitation. Program success is measured in terms of improving the safety, permanence, and well-being of children and families. The May Revision includes 6.1 million General Fund on 2020-21 for these programs, a decrease of .5 million General Fund since the Governor's Budget. When federal, state, 1991 Realignment, and 2011 Realignment funds are included, total funding for children's programs is over .7 billion in 2020-21."The proposal eliminates Foster Family Agency social worker rate increases, eliminates the Family Urgent Response System, and eliminates the Public Health Nurse Early Intervention Program in Los Angeles County."This is a time where we need to see, not cuts, but increased investment in the kinds of supports that help families meet basic needs and avoid some of the financial stresses and then receive the kinds of services and support for dealing with any issues that may trigger some abuse," said Jessica Heldman with the Children's Advocacy Institute at the University of San Diego.Heldman said they're concerned about funding to help prevent abuse and neglect, funding to foster care services, and making sure there's money to support young adults who are transitioning out of the system and have no support beyond the system.She said transitional youth leave the system at 18 or 21 and don't have a parent or legal guardian who can help with financial support or emotional support. Something as simple as a place to stay."They are high risk of some pretty poor outcomes, and it's going to take a real investment to make sure that we put them in the best position possible when they are going to be struggling," Heldman said.Heldman explained many of the youth aging out of Foster Care are losing their jobs. She cited a recent survey of about 600 transition-age foster youth across the country. It showed 65 percent of the respondents had lost their job, one in five said they are concerned about not having enough money to eat, and more than half of them had not received stimulus checks."I think people are unaware of this population of young adults and older teens who really need the support and need to be a priority or else they are going to become the parents of the next generation who are struggling economically, and the cost to that in our society is going to be far greater than the investment now to make sure that they stay on their feet," she said.Experts say a budget proposal from the Legislature released last week restores many of the cuts proposed by the governor.According to the floor report of the 2020-21 budget, “The Legislature Rejects the Governor's May Revision proposal to eliminate the Foster Family Agency social worker rate increases in 2020-21, Rejects the Governor's May Revision proposal to eliminate the Family Urgent Response System and Rejects the Governor's May Revision proposal to eliminate the Public Health Nurse Early Intervention Program in Los Angeles County among other things.”The overview of the floor report states, "The Speaker of the Assembly, the President Pro Tempore of the Senate, and the Assembly and Senate Budget Committee Chairs announced a legislative agreement on the 2020-21 state budget on June 3, 2020. This sets the stage for legislative negotiations on the budget with the Governor and his administration. The Legislature will meet the June 15 deadline to pass a balanced budget bill.""It is the responsibility of the state to ensure that children who depend on child welfare and foster care youth programs can do so confidently and without fear of abandonment, especially during these uncertain times. I have been a longtime advocate for youth, and I strongly believe that the state funding provided to these programs cannot be compromised. As budget negotiations continue, I urge the Governor's office not to balance the budget on the backs of children who need our help," Assemblymember Brian Maienschein told 10News.County of San Diego Health and Human Services representatives said the agency is monitoring the budget process, what is submitted and what the governor will sign. 6490

SAN DIEGO (KGTV) – James Prince, the owner of a recycling center in Point Loma, went to the Peninsula Community Planning Board Thursday night to try and save his business.Prince Recycling is being evicted from his location on the property of the Stump’s Family Market Place.Prince Recycling has become a controversial business in the past one or two years.  It is the only recycling center in the area, but many neighbors have started complaining that it is bringing homeless problems to the area.Dirk Stump, the owner of the grocery store, confirmed he is evicting the recycling center, ending their agreement for the past five years. The area is required to have a recycling center, and Dirk says the state could fine him more than ,000 a year for cutting ties with recycling, but at this point, he is willing to pay, because he says the center is attracting homeless and chasing away customers.  He said Mr. Prince is a good person and it was purely a business decision.“I recycle thousands of tons of material, and it’s not just from homeless,” Prince said.  “Not only that, they’re people too. What am I supposed to do? You’re homeless you can’t come in?” The planning board did not take any action on the issue. Prince says he’s not making any plans to vacate. He is getting legal help to fight the eviction. 1350

SAN DIEGO (KGTV) - Inside an MCAS Miramar courtroom Thursday, the military held a preliminary hearing for a Navy corpsman who's charged in connection with the death of a fellow Navy corpsman, HM3 Michael Vincent De Leon. A corpsman is a type of medic.ABC 10News' cameras were not allowed inside, where accused corpsman HM1 Ryan Dini appeared in his military fatigues alongside his private counsel."A cover-up is what I felt [happened] from the get-go," Jose De Leon told ABC 10News just after the hearing. He has suspected a possible cover-up since his 30-year-old son died on the Twentynine Palms military base last year.At Thursday's hearing, the prosecution argued that HM1 Dini should face additional charges related to negligence. He's already charged in part with dereliction of duty resulting in death and drunk and disorderly conduct. HM1 Dini has 19 years of service with the military.The prosecution stated that HM1 Dini and a handful of others service members including Michael were at a house party on-base where alcohol was flowing, and guns were being dry-fired the night of the death.HM1 Dini's defense denied any wrongdoing."[HM1 Dini] being the most senior individual at this going-away party failed to protect not just Michael but everyone there because they were in danger when these firearms came out," said Jose De Leon. He told us in September, "We know that the firearm was dry-fired at Michael. The firearm was put away and it came out again and according to some statements they were horsing around, and the firearm came out again and that's when Michael was killed."He said that the shooting was first called in as a suicide but ABC 10News then learned from a source with close military ties that the death was being investigated as a homicide.A prosecutor named three other service members in the hearing. Their involvement remains unknown.The prosecution told ABC 10News that in about three weeks a judge will determine whether HM1 Dini's charges will be sustained and whether he'll face additional charges.Naval Criminal Investigative Service wrote to ABC 10News on Thursday that the investigation is still open. 2149

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