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As questions arise over when a coronavirus vaccine should be granted FDA approval, the leaders of several major pharmaceutical companies announced they have signed a pledge not to rush the development of a vaccine.The companies, AstraZeneca, BioNTech, GlaxoSmithKline, Johnson, Merck, Moderna, Novavax, Pfizer and Sanofi, released a joint statement on Tuesday confirming the pledge.The pledge includes the following points:Always make the safety and well-being of vaccinated individuals our top priority.Continue to adhere to high scientific and ethical standards regarding the conduct of clinical trials and the rigor of manufacturing processes.Only submit for approval or emergency use authorization after demonstrating safety and efficacy through a Phase 3 clinical study that is designed and conducted to meet requirements of expert regulatory authorities such as FDA.Work to ensure a sufficient supply and range of vaccine options, including those suitable for global access.There has been pressure on both the FDA and manufactures to develop and approve a vaccine for the coronavirus. There have been more than 190,000 coronavirus-related deaths in the US since March, and the economic impact of the virus has cost millions of jobs.While most developed countries have not had the same public health pain as the US, the economic impact of the virus has been felt worldwide. The International Monetary Fund estimates a nearly 5% loss in global GDP in 2020.In Russia, the country claimed to begin distributing a coronavirus vaccine despite US-based vaccine candidates likely being months away from being able to demonstrate efficacy.The pressure domestically has also ratcheted up as President Donald Trump has suggested a vaccine could be ready by this fall’s presidential election."We're going to have a vaccine very soon... maybe even before a very special date, you know what date I'm talking about,” Trump said on Monday.In late August, the CDC told states to begin to prepare distributing a vaccine by Nov. 1. But Surgeon General Jerome Adams said that just because states will be ready to help distribute a vaccine on Nov. 1 does not mean a vaccine will be ready by then."We've always said that we're hopeful for a vaccine by the end of this year or the beginning of next year,” Adams told Good Morning America."We want to make sure states are available to distribute it," he added.The companies signing on the pledge said that the FDA has strict protocols for vaccine candidates. A typical vaccine trial takes one to three years, but the companies believe only a safe and effective vaccine will be granted approval.“FDA has established clear guidance for the development of COVID-19 vaccines and clear criteria for their potential authorization or approval in the US,” the companies wrote in the pledge. “FDA’s guidance and criteria are based on the scientific and medical principles necessary to clearly demonstrate the safety and efficacy of potential COVID-19 vaccines. More specifically, the agency requires that scientific evidence for regulatory approval must come from large, high quality clinical trials that are randomized and observer-blinded, with an expectation of appropriately designed studies with significant numbers of participants across diverse populations.” 3296

At least 8 major hotel-casinos are currently undergoing renovations and the cost is half a billion dollars.Some of the resorts involved include Monte Carlo, Caesars Palace, Flamingo, Planet Hollywood and Harrahs.They are hoping the renovations will attract more guests and that those guests will be willing to pay more to stay at upgraded properties.  364

As screen time becomes a bigger part of students’ lives, preserving their vision is something to keep an eye on.Dr. Lauren Schneider, an ophthalmologist who has been treating patients in New York and Connecticut for six years warned screen time can cause a number of symptoms, including squinting and eye-crossing.“We do know that prolonged near work can place some children at risk for progressive myopia, which is worsening nearsightedness,” Dr. Schneider said.Doctors say tips on preserving your kids' vision during remote learning include making sure they keep a safe distance from their devices — at least 15 inches away from the screen is recommended — having them take screen breaks every 20 minutes and investing in a blue light blocker, which can be put on devices or glasses.“Some of our data suggests blue light emitted from our electronic devices may potentially be harmful long term to the center of the retina,” said Schneider Sunday.As school districts in the tri-state area continue to reopen this fall with full remote or hybrid learning models that include screen-based instruction, eye protection is another safety measure doctors say parents should have their sights on.“We want to make sure that while our students are hard at work which is going to require a lot of time in front of the computer that we’re avoiding unnecessary eye strain," Schneider said.According to medical experts, the full long term impacts on the eyes from remote learning are still being looked at, regular eye exams are highly recommended.For more tips and resources:www.visiontolearn.orgwww.childrenseyefoundation.orgwww.kidshealth.orgThis story was first reported by Jennifer Bisram at PIX11 in New York City, New York. 1726

ATLANTA — President-elect Joe Biden is thanking Georgia voters for delivering him the state in last month’s election and asking them to follow up by electing Democratic Senate candidates Jon Ossoff and Raphael Warnock.Biden traveled to Atlanta for a post-election rally Tuesday to help the Democrats looking to knock off incumbent Republican Sens. Kelly Loeffler and David Perdue in Jan. 5 runoffs. It's the president-elect’s second foray outside the Wilmington, Delaware, area since last month’s election.Biden is the first Democratic presidential candidate to win Georgia since 1992. He'll return to the state Tuesday to campaign alongside Jon Ossoff and Raphael Warnock ahead of the Jan. 5 runoff elections that will determine Senate control.As it stands, the Republicans hold a 50-48 majority in the upper chamber. But if both Ossoff and Warnock win their January runoff elections, Democrats would take control of the Senate by virtue of vice president-elect Kamala Harris' tiebreak vote.WATCH RECAP:A day after the Electoral College affirmed his victory, Biden used his remarks to call for unity. But he also made the case that he badly needed “doers and not roadblocks" once he takes office next month.“We can get so much done, so much that can make the lives of the people of Georgia and the whole country so much better,” Biden said. “And we need senators who are willing to do it, for God’s sake.”If the Democrats win both Georgia runoffs, Biden would enter office with Democratic control of both chambers of Congress, giving him far more leverage to push his agenda.“Are you ready to vote for two United States senators who know how to say the word ‘yes’ and not just ‘no’?” Biden said at the drive-in rally.According to the Associated Press, Warnock and Ossoff could benefit from riding Biden's coattails. Biden finished with more votes than any candidate during the 2020 election — but Ossoff ran about 88,000 votes behind President Donald Trump and about 100,000 votes behind Biden.Trump campaigned for Republican candidates, Sen. Kelly Loeffler and Sen. David Perdue, earlier this month. 2109

As the nation mourns the passing of Sen. John McCain, Arizona Republicans are holding a Senate primary Tuesday in which one of the candidates suggested the announcement that McCain was stopping medical treatment was timed to hurt her campaign.Kelli Ward, a former state senator who has courted the far-right during her campaign, suggested on Facebook Saturday that McCain's family released its statement saying the senator was ending medical treatment for brain cancer was timed to hurt her chances of winning Tuesday's primary.Ward staffer Jonathan Williams posted that he wondered whether McCain's statement was released "to take media attention off" Ward's campaign, which was beginning a statewide bus tour. "I'm not saying it was on purpose but it's quite interesting," Williams wrote."I think they wanted to have a particular narrative that they hope is negative to me," Ward responded, according to a screenshot posted by the The Arizona Republic.The news broke that McCain had died hours after Ward's comment. Ward's campaign did not respond to a request for comment on the Facebook post.On Monday, less than two days after McCain died of brain cancer, Ward tweeted, "Political correctness is like a cancer!"The attacks and insensitive remarks about McCain are just the latest in a heated primary race that has seen all three candidates align themselves with President Donald Trump, who attacked McCain relentlessly for three years, rather than McCain or retiring Sen. Jeff Flake, whose seat they are seeking to fill.Their decisions show how the path McCain cut through the Trump era -- breaking with the President on foreign policy, health care, immigration and more -- complicated his relationship with diehard Republicans in a state where the GOP electorate is now demanding fealty to Trump.Ward faces Rep. Martha McSally and former Maricopa County Sheriff Joe Arpaio in Tuesday's primary for Arizona's other Senate seat. McSally is seen as the strongest general election candidate to face likely Democratic nominee, Rep. Kyrsten Sinema.McCain fended off Ward's challenge in a 2014 primary. Since then, she's made a series of insensitive comments as McCain battled brain cancer.She called on McCain to step down last year, calling him old and near "the end of life" before his diagnosis and said afterward he should resign "as quickly as possible."Ward closed the race barnstorming the state on a bus tour with right-wing media personalities Mike Cernovich and Tomi Lahren, as well as Rep. Paul Gosar."Are we going to elect another senator cut from the same cloth as Jeff Flake and John McCain?" Ward asked the crowd at a campaign event Friday, eliciting shouts of "No!"After McCain's death, Ward tweeted: "We are saddened to hear of the passing of @SenJohnMcCain. His decades of service will not be forgotten by the men & women of Arizona. May God grant the McCain family comfort and peace during this difficult time."McSally, the Republican establishment's preference in the race, has mostly remained silent on McCain during the primary.But McSally's omission of McCain's name when touting her support for the National Defense Authorization Act, which was named in McCain's honor, when McSally joined Trump at a signing ceremony at Fort Drum in New York, angered McCain's daughter Meghan McCain.McSally's "inability to even mention my father's name when discussing the bill named in his honor is disgraceful (just as it was with Trump)," Meghan McCain tweeted. "I had such higher hopes for the next generation of leadership in my home state."Throughout the campaign, McSally has sought to avoid any distance between herself and Trump.On Thursday, McSally sought to dodge last-minute controversy that could undercut her primary campaign, repeatedly avoiding reporters' questions about whether she considers Trump honest and trustworthy. The questions came after Trump attorney Michael Cohen's guilty plea and claim that Trump knew about hush payments to alleged mistresses during the 2016 campaign. McSally refused to address Trump, saying only that Cohen was "all over the map, contradicting himself, lying in order to save his ass."After McCain's passing, McSally tweeted, "John McCain was one of Arizona's greatest Senators, one of our country's finest statesmen, and an American hero who risked his life to defend this great nation. He loved this state, and he loved this country."I pray that God comforts Cindy and the entire McCain family. My heart is with them, and Arizona grieves with them."Arpaio, who was pardoned by Trump last year after being convicted of criminal contempt related to his hardline immigration tactics, complained in a since-deleted tweet on Friday that Cindy McCain had blocked him on Twitter."I tweeted out my thoughts & prayers for" McCain, his campaign account tweeted, and Cindy "BLOCKS me on twitter?"Arpaio tagged Trump and several news outlets in the tweet.The-CNN-Wire 4934

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