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A surge in COVID-19 cases is further straining the already-depleted supply of prescription drugs in the U.S., according to researchers and doctors at the University of Minnesota."The supply lines are really stressed and stretched," said Dr. Stephen Schondelmeyer, a co-principal investigator for the Resilient Drug Supply Project at the University of Minnesota.Schondelmeyer's work focuses on critical drugs and their supply chains. He tracks the supply chain process for every drug on the marketplace — more than 100,000 in total.Most of the prescription drugs used by Americans are made outside of the country — meaning the U.S. is reliant on foreign companies to manufacture the drug and shipping companies to deliver them safely."We're identifying where it comes from — the first thing you need to know is about 70% of all the drugs that come into the U.S. marketplace are made outside of the US.," Schondelmeyer said.He and his team want to predict and identify when and where there will be failures in the system. Right now, the U.S. has a "fail and fix" system — and right now, there are some critical breakdowns in the supply chain."Seventy-five percent of the COVID-19 drugs are currently in shortage," Schondelmeyer said. "That means three-fourths of the drugs we're using for COVID-19 were already in shortage, and that's before we had this last surge we're seeing.""We should, as a matter of national policy, have a map like we're building of the global drug supply from the beginning all the way until the drug reaches the patient," Schondelmeyer said.But it's not just COVID-19 drugs that are in short supply. Dr. Beth Thielen, an assistant professor of pediatrics at the University of Minnesota Medical School and an infectious disease physician, says even some routine drugs are hard to come by."As a physician working in the hospital — the University of Minnesota — we're a big urban center and yet we're regularly dealing with this issue of shortages in routine things like antibiotics," Thielen said. "It's very concerning to think about the supply chain breaking down and seeing drugs not available in pharmacies or the hospital."Doctors say COVID-19 has unmasked a problem that's been a concern for decades. The pharmaceutical supply chain is complicated and dependent on other countries — and there are supply and demand dilemmas."Start the conversation now with your healthcare provider," Thielen said. "There might be some within class substitutions of medicines, so a drug that is related may not be the exact same drug but might fulfill the same purpose."Schondelmeyer adds that anyone with a regular prescription should ask their doctor about getting a 90-day supply of essential drugs — but adds that there's no reason to hoard medication."We shouldn't panic. We shouldn't treat drugs like we did toilet paper and stock up on so much that we're totally out — and that's an example of what can happen when there's rumors of shortages," Schondelmeyer said. "People act out of fear, and they hoard more than they really need."In the meantime, Schondelmeyer is pushing for a national stockpile of critical medications, so that the U.S. is covered should there be a complete breakdown in the supply chain. 3236

A plane dragging the Confederate flag was seen circling Bristol Motor Speedway prior to the NASCAR All-Star race Wednesday night.Videos shared to Twitter and other social media sites show the plane dragging the flag, along with the website for the Sons of Confederate Veterans.NASCAR banned the Confederate flag from racetracks in June, following the death of George Floyd and resulting weekslong protests against police brutality and systemic racism. 459

A telltale facial expression and anxious elevator behavior — both jumped out as odd signs to body language expert Dr. Jack Brown that something was not right with Stephen Paddock."There's not any one thing that says 'this guy's a killer,' or 'whoops, this is an absolute call the police right now kind of behavior,'" said Dr. Brown. "But there are definitely anxiety tells and abnormal behavior to the point where it depends on your screening level."RELATED: Video shows Stephen Paddock's actions at Mandalay Bay before shootingMeaning how much attention was being paid by those watching Paddock's movements at Mandalay Bay, if anyone was watching the high roller as he came and went over days, gambling all night long and carting in load after load of luggage."He seemed like he really went out of his way to make it look casual," said Dr. Brown. "Take up the luggage not all at once - multiple trips - he really planned it out."So calculated, Brown said it was spooky.And a spooky demeanor is part of what he sees in one of Paddock's facial expressions."That center forehead going up, a little bit of a mouth smile, that's a person with low empathy and low sincerity and that's also got a very high correlation with sociopathic behavior."It's an expression we all make once in a while, but Brown said those who do it a lot raise red flags.  He blogs about the expression on the faces of convicted serial killers and foreign leaders like Russian President Vladimir Putin.  Dr. Brown also noticed Paddock's elevator behavior."He's got his legs crossed and his center of gravity is way off," he said.He said that might not seem abnormal in the moment, but in hindsight it shows significant anxiety. In another video clip, Paddock's "got his hands in his pockets and he's doing this (rocking back and forth) at the elevator. That's significant for anxiety."And while the behavior itself isn't necessarily incriminating, Dr. Brown said it's all about the context."And that's particularly - the elevator thing was extremely out of context," he explained.Once inside the elevator, he noted how - multiple times - Paddock backs into the corner even though he's alone."And the corner he chose was the corner with the camera, such that the camera showed the top of his head and not his face," Dr. Brown said. "Even if there wasn't a camera, that's odd behavior. That might be something, if I was screening for potential nefarious behavior, that I would look for."MGM Resorts issued the following statement: 2586

A Virginia judge has extended the deadline for Virginians to register to vote for two days after a state-run website crashed.The Associated Press reports that U.S. District Judge John A. Gibney, Jr. announced Wednesday that Virginians can now register to vote through this Thursday.The state website where Virginians can register online crashed Tuesday when Gov. Ralph Northam said a fiber optic cable was accidentally cut in a roadside project.This story is breaking and will be updated. 496

A Mississippi school district has apologized and a high school band director has been suspended after the band staged a halftime skit that depicted police being held at gunpoint.The controversial skit came as the Forest Hill High School band from Jackson performed Friday during a football game against Brookhaven High School to the south. It shocked many at the game in Brookhaven, where just six days earlier two police officers were killed in a shootout with a suspect."I was sad because of what happened last weekend, and it felt like they were making fun of it," Sarah McDonald, a Brookhaven High School student, told CNN affiliate WJTV.A woman who said she was a graduate of Brookhaven High School found the performance insensitive."I was shocked by the halftime performance just because of everything that our community is going through," the woman told CNN affiliate WLBT. "No disrespect to Forest Hill, when they decided to do a performance, they should've took that into consideration that we were already going through a lot at this time. We are still trying to figure out what needs to be done about the situation." 1135