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Supporters of right-to-try argue that the legislation is needed because most terminal patients are too sick to be selected to participate in clinical trials and it takes too long for promising treatments to be approved.Joffe argued that the right-to-try approach to providing access to unapproved drugs early in their development could put patients in harm's way, as patients receiving the drug are often in very fragile health, doctors often lack the information needed to administer the drugs safely, and little may be known about their risks and benefits, he said.Joffe pointed to certain stem cell therapies as treatment approaches that appear promising but have turned dangerous when unregulated."Another thing I'm worried about is that there's going to be a bunch of shady actors that are going to pop up that are going to start to try to take advantage of the right-to-try law to say 'we can provide these sort of experimental therapies, if you want to call them that, to patients without needing to go through the FDA,'" Joffe said."We've already seen some of that in the stem cell clinics popping up around the country that try to provide stem cell treatments for a host of problems: eye problems, heart problems," he said. "While there are legitimate efforts to develop effective stem cell therapies, a lot of these clinics that are popping up around the country that are poorly regulated are taking people's money and they are hurting people."On the other hand, the treatments available under right-to-try laws are already in clinical trials, Coleman said, adding that "this law isn't replacing the existing FDA expanded access program; it's just opening up another avenue.""No person is going to be forced to take an investigational drug. No doctor is going to be forced to request an investigational drug, and no drug company is forced to provide an investigational drug, if they don't think it's the right fit for a patient," she said."It's only for people who say, 'I understand the risk. I know this drug is not fully approved. It may not help me, but my doctor and the drug company think it could, and I want to try,'" she said. "Basically, if the FDA says that a drug is safe enough to be used in trials on humans, then it's safe enough for a dying person to make their own choice about whether or not they would like to try it when they can't get into a clinical trial."  2395

Starting now through the holidays, hundreds of Kroger stores across the country will host "Geoffrey's Toy Box" -- a collection of toys put together for the holiday season that were exclusive to Toys "R" Us. 206

State and national emergency officials said they had no immediate reports of damage from the latest shake, but schools were cancelled across the state on Monday. 161

That includes woodland, modern options for baby boys and baby girls and a gender-neutral option. There are also boho chic and modern grey options in the registry.Parents may use their mobile phones to complete their registries with Walmart."To make sure parents can find everything they need, we’ve added thousands of new items to Walmart.com over the past year, including products from BOB, Jujube, nanobébé, Owlet and 420

That's all I said. But for me, it was the death of the hero. That was the death of my dream, she said. Going forward, she said she gave him only her cheek to kiss and no longer looked him in the eye. 199

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