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SAN DIEGO (KGTV) -- In one San Diego neighborhood alone, around a half dozen residents have reported seeing rattlesnakes dangerously close to their front doors.The Department of Fish and Wildlife says avoid tall grasses and heavy brush if you can. And if your kids are playing in snake country — ditch sandals for a pair of boots.RELATED: Warm temps brings rattlesnake sightings across San Diego 408
SAN DIEGO (KGTV) — It’s one of the few drugs shown to help fight the novel coronavirus, and a large federal study on remdesivir just entered a new phase.Previous research sponsored by the National Institute for Allergy and Infectious Disease showed remdesivir shortened recovery time in hospitalized COVID-19 patients on average from 15 days to 11 days.Now scientists and doctors are racing to find the perfect cocktail against COVD-19 by blending remdesivir with other drugs.California-based Gilead Sciences originally developed the drug to fight Ebola, but remdesivir was never approved. Gilead Sciences has offices in Oceanside.The drug works by interrupting the virus’ ability to replicate.“Remdesivir acts by shutting down virus production,” said Dr. Peter Chin-Hong, an infectious disease expert at University of California San Francisco. “It just forces the virus to stop making virus children.”Dr. Chin-Hong is studying remdesivir as part of the NIAID research.The problem is that stopping the virus from replicating isn’t enough for some severely ill patients. They suffer from a second problem: massive inflammation from the immune system’s war with the virus.That’s why scientists are trying a cocktail approach.“You have the virus to take care of, but you also have the body's response to the virus, which is inflammation, that you also have to take care of,” said Dr. Chin-Hong.Researchers started testing the first drug cocktail in May, using an arthritis drug called baricitinib that tames inflammation.But as the data on that part of the study gets crunched, researchers began testing the second cocktail this month, a combination of remdesivir and interferon beta.“Interferon beta is something we produce naturally to fight viruses,” said Dr. Chin-Hong. He said studies have shown people who don’t produce enough interferon beta struggle to fight off the virus.Researchers selected interferon beta after two small studies showed promising results against the coronavirus.Interferon beta can both reduce inflammation and kill viruses, so doctors are hoping it will be a potent one-two punch with remdesivir.Dr. Chin-Hong said he and other researchers started administering the new cocktail this month.Some patients will receive the cocktail, some will receive a placebo, and some will get remdesivir only. This kind of clinical trial is called an adaptive trial, which the FDA started encouraging in 2004. After each phase, the winning drug or cocktail will be tested against a new challenger.Dr. Chin-Hong said the eventual cocktail may include three or more drugs, similar to HIV medication. 2617

SAN DIEGO (KGTV) — If there's one thing Californians know, it's that guacamole is always extra.Expect this weekend! National Chip and Dip Day comes on Saturday, but the fun starts Friday. Rubio's is giving away free chips and guacamole with any purchase on Friday and Saturday in celebration of the delicious event. Just present this coupon with any purchase and dip into some delicious freebies.At the very least, break open a bag at home and kick back with a handful of chips and side of dip. 502
SAN DIEGO (KGTV) -- It's almost time for back to school and that means it's time to go shopping and gather all those essentials. While some items may be obvious on your shopping list, others are more obscure. We've compiled a list of back to school tech as you prepare to make that back to school shopping list. Check out the items below for more: Livescribe – 3.5 stars on AmazonThis nifty little gadget will come in handy for those long, note-taking days. With Livescribe, you can record everything you write and hear so you don’t miss a thing, according to Amazon. Then, replay your meetings or lectures simply by tapping on your notes. Native Union Key Cable – 5 stars on AmazonAlways losing that phone charger? The Native Union Key Cable attaches to your keychain so you never have that problem again (unless you can’t find your keys, of course.) The charger is compatible with most devices, according to Amazon. Casio Touchscreen with Stylus Graphing Calculator – 4 stars on AmazonTime for upper-level math classes? This graphing calculator has a 4.8 inch touchscreen with a stylus. The calculator also has an advanced computer algebra system for all those tough-to-solve math problems. iHome IBT29 Bluetooth alarm clock – 4 stars on AmazonDoes your student have a hard time waking up? The iHome Bluetooth dual alarm clock radio with speakerphone may be the solution (and it changes colors, which is just cool.) The alarm can be set to Bluetooth audio, FM radio or built-in tone. Pixie (4-pack) – 3 stars on AmazonDoes your student lose things often (who doesn’t?) The Pixie shows you at a glance the exact distance in feet and inches to the lost item, according to Amazon. Click here to scroll through a slideshow of the items listed above. 1756
SAN DIEGO (KGTV) - If you're driving along I-5 in Logan Heights, you might see Frankie Ortiz in a mariachi costume on the bridge above you.He told 10News Photojournalist Zach Wonderlie, he just wants to make San Diego smile!Ortiz said he gets encouragement on social media from people who enjoyed seeing him dance. 332
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