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SAN DIEGO (KGTV) — When you are out in public, it is virtually impossible to tell who has immunity to the coronavirus and who is susceptible.A San Diego-based company is trying to change that by developing two new COVID-19 monitoring systems that are as easy as checking someone’s forearm.Diomics is developing a device that looks like a nicotine patch that the company says can reveal the presence of SARS-CoV-2 antibodies in 24 to 36 hours. The patch is intended to be worn for one to two weeks, offering people a way to monitor -- and potentially display -- their infection status, according to CEO Anthony Zolezzi.When the patch, named Diocheck, detects antibodies circulating in the blood, it turns red.“We think this is an integral piece of getting things back to normal,” Zolezzi said. “This can get the country back operating and get us comfortable that the people around us aren’t infected.”A second device, made from thousands of tiny polymer beads, can be injected into the skin and offer COVID monitoring for six months to a year, Zolezzi said. The company is still testing how long the test can stay active before it’s safely absorbed by the body.The company plans to launch clinical trials at UC Irvine next month.Zolezzi envisions the tests would be useful for employees in numerous sectors, including the airline industry, the cruise industry, the gambling industry and the military, offering a new way to detect and rapidly quarantine infected individuals.Once a coronavirus vaccine is released, the tests could be a useful companion, he said, since it will likely take several weeks to develop protective antibodies after inoculation. An individual wearing the patch, for example, could find out when they have antibodies circulating in the blood.The tests could also show when a person begins to lose antibodies. Studies have show individuals with a mild coronavirus infection lose antibodies after a few months, and it’s common for vaccines to require multiple doses.“This patch will show you, when the color dissipates, it’s because your antibodies have dissipated,” Zolezzi said. “That’s the time when you need to get a boost, or some type of prophylaxis.”The small biotech firm with less than 20 employees is leveraging technology that’s more than 100 years old.In 1907, a French physician named Charles Mantoux developed an injection test for tuberculosis that produces a raised, red dot on the skin when the bacteria is detected. This is the standard test given today.“All we’re doing is modernizing it,” Zolezzi said. The company’s patented slow-release material allows for much longer monitoring, he added.Diomics was making skin care, wound care and diabetes products before the pandemic shifted the company’s focus. Their components are FDA approved individually, but will need new approval for this use, Zolezzi said.Zolezzi said production is underway, but the company is hoping to partner with a large drugmaker to rapidly scale up manufacturing. Their goal is to have products on the market by the end of the year. 3055

SAN DIEGO (KGTV) - Wedged in between the rush on malls of Black Friday and the online giants of Cyber Monday sits Small Business Saturday.San Diego’s independent retailers are hoping to win some of your holiday shopping dollars and earn recognition for what they do for their neighborhoods. Some areas are hosting street fairs while others will have deals and longer store hours.Small Business Saturday was created in 2010 by American Express to support small stores. An average of 67 cents for every dollar spent at a small business stays in the community, according to the company.NORTH COUNTY COASTALCardiff 101, Encinitas 101 and Leucadia 101 Main Street have teamed up for their biggest Small Business Saturday yet. Look for live music, sidewalk sales, limited edition art and a beer garden in Cardiff. Many stores have special offers and giveaways. Events run from 11 a.m. to 3 p.m.CHULA VISTAVisit jewelry stores and bakeries in Chula Vista before stopping at a restaurant or brewery along Third Avenue, the historic downtown area. Read moreOCEAN BEACHThe Ocean Beach Main Street Association is welcoming shoppers with a day of interactive arts and music pop-ups. The event, now in its ninth year, will feature a walk-through sculpture, magic show, and Instagram opportunities like a ‘Greetings from Ocean Beach’ giant postcard. The activities run from 10 a.m. to 4 p.m. in the Newport Avenue and Voltaire Street business districts. Read more LITTLE ITALYLittle Italy is known for its boutiques and art galleries along with fantastic food. The community association is welcoming shoppers to pick up a “Shop Small, Shop Little Italy” passport at local businesses. Expect big discounts and later hours at stores. Read moreNORTH PARKThe North Park Main Street association has freebies for shoppers on Small Business Saturday. Bring your receipts to the booth at the corner of University Avenue and Ray Street to receive a mug, t-shirt, or Bluetooth speaker. Many of the community’s popular restaurants also have discounts on gift cards. Read moreHILLCRESTSpending big at Hillcrest’s shops and restaurants? Anyone who has a receipt for a purchase of or more can receive a Shop Small gift bag filled with more than 0 in gift certificates and giveaways like beauty products, coffee drinks and meals at neighborhood restaurants. You can look for the Shop Small Welcome Station at the Rite Aid parking lot at Fifth Avenue and Robinson from 9 a.m. to 4 p.m. Read moreEL CAJONEast County takes Small Business Saturday to new heights with Holiday Lights on Main. You can see live music, go ice skating, or visit Santa’s Village in addition to shopping. Events run from 2 p.m. to 7 p.m. on Main Street. The Christmas tree lighting is at 6 p.m. Read moreESCONDIDOShop, eat, drink and play all day in downtown Escondido! You can pick up a free shopping bag with special offers at one of several welcome stations. You can also enter to win free tickets to a show at California Center for the Arts. Read moreOCEANSIDEShop and sip in downtown Oceanside, where wineries and breweries have ‘Sip Stops’ to enhance your holiday shopping experience. You can also enjoy live music and special offers at stores. The event runs from 2 to 5 p.m. with tickets available at the Oceanside Museum. Read moreLA JOLLAWave to the Children’s Pool seals and spend your Saturday enjoying La Jolla’s boutiques! Independent store owners have special offers for you at locations in downtown La Jolla and near the Cove from 10 a.m. to 6 p.m. Read moreFind other small businesses participating in Shop Small here. 3604

SAN DIEGO (KGTV) -- Two men are dead after a shooting near a Mountain View park Sunday afternoon. Two black men, ages 33 and 37, were shot in the upper body, San Diego Police said. Both men died at the hospital.The shooting happened around 1:20 p.m. Sunday near South 40th Street and Ocean View Boulevard. Police said the victims were standing near the Mountain View Community Center when they were shot.The suspect is described as a black man wearing dark clothing.South 40th Street was closed between Teak Street and Hemlock Street while police investigated the crime.The circumstances leading up to the shooting are not known.Anyone with information is asked to call the homicide unit at 619-531-2293 or Crime Stoppers at 888-580-8477. 776

SAN DIEGO (KGTV) -- While San Diego County remains in the red tier of California’s tiered reopening plan, many local gyms and fitness centers continue to struggle to operate at 10 percent capacity.For some, it’s just not enough to survive, and business owners have to make difficult decisions.“Our rent doesn’t change whether we have one person in class versus 25,” said Taylor Hollenkamp, owner of BarreBody Studios in Pacific Beach and Tierrasanta.Days ago, Hollenkamp sent a notice out to members of BarreBody Studios, announcing the fitness studio would be closing after nearly a decade in business.“With no end in sight of things going back to normal, I had to make the decision to close permanently because the business is just hemorrhaging money,” she said.Others in the San Diego fitness industry can relate to the pain Hollenkamp is experiencing.“You can’t run a business, you can’t advertise, you can’t bring in new clients,” said Matt Ceglie, a personal trainer, and co-creator of the Strongist app, which allows users to track and log workouts.He said he has not been able to train any of his clients in a private Carmel Valley gym since March.“I had about 25 clients that I worked with on a weekly basis, now I train about nine of those clients in their homes or remotely,” said Ceglie. “It’s almost impossible right now in the tier we’re in to run your gym at 10 percent capacity.”When it comes to California’s reopening tiers, San Diego is currently in the red tier, allowing gyms and fitness centers to operate at 10 percent capacity.If San Diego County’s COVID-19 numbers improve and we move to the orange tier, they could open inside at 25 percent capacity. In the yellow tier, which is considered the best, it’s 50 percent capacity.With no exact solutions to the loss of income or path to a full reopening, more small business owners have to say goodbye to the dreams they worked hard to make a reality.“I’ve been building this business for 25 years, and it goes away just like that,” said Ceglie.“I was so passionate about the fitness industry, and this has just caused such a heartache for me and so much stress that it’s not fun for me anymore,” said Hollenkamp. “This has been my career, and I don’t know what I’m going to do after this.” 2269

SAN DIEGO (KGTV)- A new technology just reached San Diego and Border Patrol agents say it’s going to help them do their jobs faster, easier and more efficiently. They’re called Mobile Video Surveillance Systems. Each unit is grounded to a Ford F150, the controls to operate the cameras mounted on a mast in the bed of the truck are inside. San Diego is the second place in the nation to have truck like these. Border Patrol says they’ll be rolling out in just a couple days. The first place to have Mobile Video Surveillance System trucks is Rio Grande Valley, Texas. Michael Scappechio is a supervisory with Border Patrol and he tells 10 News, “the looming threat of the migrant caravan in Tijuana and more people potentially on the way we need to make sure we’re prepared for that”. The two cameras allow the agents to see two pictures at all times, a daytime camera and an infrared camera. While Scappechio says the need for this kind of technology is needed in San Diego, it’s their increased rate of arrests that landed the trucks here, “nearly a 90 percent increase is significant, that’s going to get attention, that’s going to get resources, that’s going to get man power, infrastructure and technology”.Border Patrol tells 10 News these trucks won’t replace the border wall but instead, will go hand in hand with it. 1334

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