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Trimble says he is planning a meeting with city staff to go over how to improve the program as it goes into its second, and potentially final, year.  154

This is really a law for people who are very sick, who have exhausted all treatment options and who cannot enroll in a clinical trial, said Starlee Coleman, senior policy adviser at the Goldwater Institute, a conservative public policy think tank based in Phoenix that supports right-to-try legislation."For people living in a state where right-to-try is already on the books, they already have the ability today to work with their doctors directly to approach a drug company with a drug in clinical trials and ask for the option to try that drug outside of the clinical trial," she said. "For people living in the 12 states without a right-to-try law, today they don't have this option, but if the federal law passes, they will have the option."Some opponents argue that the bill won't change much but could have a detrimental effect on how the FDA safeguards the health of the public.Dr. Steven Joffe, professor in medical ethics and health policy at the University of Pennsylvania's Perelman School of Medicine, co-authored a perspective paper about such concerns, published in the New England Journal of Medicine last month.The paper notes that the FDA already has expanded-access policies, sometimes called compassionate use, to give terminally ill patients without other options access to investigational medical products outside of clinical trials.About 99% of submitted applications for expanded access to almost 9,000 investigational drugs were allowed to proceed over a 10-year period between January 2005 and December 2014, according to a study by FDA researchers, published in the journal Therapeutic Innovation & Regulatory Science in 2016."Emergency requests for individual patients are usually granted immediately over the phone and non-emergency requests are generally processed within a few days," FDA Commissioner Dr. Scott Gottlieb said in a statement last year. 1885

These exceedances call into question the state's ability to protect the public and administer its SDWA programs in a manner consistent with federal requirements, he said. 170

They have been open and transparent and incredibly authentic with their apology, he said. "I think they're going to have more people wanting to go to KFC than less ... as a result of this." 189

This was important for us to observe. Nick has sincerely apologized and quickly taken steps to educate himself and make amends. On that basis and given a belief that this moment calls for dialogue, we will move forward with Nick and help him advance this important conversation, broadly. FOX condemns all forms of hate directed toward any community and we will combat bigotry of any kind,"" Fox concluded." 498