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HENRICO COUNTY, Va. -- Scores of family, friends and even a lawmaker or two helped a Virginia woman celebrate a milestone birthday over the weekend.Ms. Annie Pie turned 100 years old Sunday and the Henrico County community turned out to help her celebrate.Because of the COVID-19 pandemic, Ms. Pie was honored with a drive-by parade with plenty of waves, well-wishes and lots of honks."The Lord is good, honey... to let me live this long to see this day," Ms. Pie said. "I never had a day like this before and I always love people and I think they love me, too."Happy Birthday, Ms. Pie!This story was originally published by Todd Haas and the web staff at WTVR. 669

Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

From the 2001 anthrax attacks?to the Unabomber case, using the mail or other services to deliver deadly weapons has a long and frightening history in the United States.Wednesday's suspicious packages that were sent to several Democratic leaders -- including former Presidents Obama and the Clintons -- and the explosive device that triggered the evacuation of CNN's New York bureau were the latest in a long list of similar incidents, some that proved deadly.There have been no reports of injuries or deaths in the latest incidents.Here are some of the more notable examples of how criminals have weaponized US mail or package delivery services: 663

Here is when the driver first pulled up to the protesters tonight in Denver, you can hear people urging him to turn around. During the next few minutes, I saw the driver shaking his head in apparent disbelief and using his cell phone, perhaps to take pictures. pic.twitter.com/TSAzfipida— Shelly Bradbury (@ShellyBradbury) September 24, 2020 349

From the International Space Station: I voted today— Kate Rubins pic.twitter.com/DRdjwSzXwy— NASA Astronauts (@NASA_Astronauts) October 22, 2020 152