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SAN DIEGO (KGTV) — As Pfizer’s COVID-19 vaccine rolls out to healthcare workers, at least four have had severe allergic reactions after getting the shot.The cases include two healthcare workers in Alaska and two in the UK. In the UK cases, both individuals carried epipens.“So these were people with a history of severe allergies and not just severe allergies like you got hives, but they had allergies where they encounter certain things in the environment and their body shuts down,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.All four have apparently recovered.At this point, doctors aren’t sure what caused the reactions. Generally speaking, allergies when your immune system overreacts to something harmless.Pfizer’s vaccine has 10 ingredients that fit into four categories.The active ingredient is mRNA. These are temporary genetic instructions for your cells to build a small, harmless fragment of the virus’ shell to train your immune system, similar to setting up a punching bag to train a boxer.Then there are fats to stabilize and transport the mRNA, salts to maintain the pH, and sugar to prevent the solution from degrading while freezing.All the ingredients are considered standard. Dr. Chin-Hong says he was struck by what’s not in the vaccine.“They didn't have egg products or any of those kinds of things that people might be allergic to,” he said. “They didn't have live virus, which might also elicit a response.”The only ingredient with a history of allergic reactions is polyethylene glycol, or PEG, one of the fats that acts as an oily bubble for the mRNA.PEG is also in Moderna’s vaccine and it’s common; it’s found in ultrasound gel, laxatives, injectable steroids and other products.Although PEG allergies are rare, the FDA says people who are allergic to any of the 10 ingredients should not get the vaccine.However, experts say people with common allergies should not worry.“A lot of people have minor food allergies or bee-sting allergies or peanut allergies or environmental allergies,” said Dr. Christian Ramers of Family Health Centers of San Diego. “They may even carry an epi-pen because sometimes it gets severe. Those people would not be excluded from getting this vaccine.”The American College of Allergy, Asthma and Immunology issued guidance saying people with those common allergies, including to latex and medications, “are no more likely than the general public to have an allergic reaction” to the vaccine.After every shot, people who get vaccinated have to wait 15 minutes so healthcare workers can monitor them for a reaction. Should one occur, interventions like epi-pens are very effective.The FDA said people with a history of allergic reactions to vaccines or injectable drugs can still get the shot, but they should wait 30 minutes for slightly longer monitoring.The odds of having a severe allergic reaction to any vaccine is about 1 in 760,000. That means you’re more likely to be struck by lightning in a given year, which the CDC estimates is about 1 in 500,000. 3048

SAN DIEGO (KGTV) — County health officials say a dead Cooper's hawk found in Ramona has tested positive for West Nile Virus.The hawk is the second bird to test positive for the virus in San Diego County in 2019. Two county residents have also tested positive for the virus this year, but officials say both were bitten and contracted the virus in other counties. Across the state, 184 people have tested positive for the virus and five people have died this year.County health officials are now reminding the public to protect themselves from mosquitoes that may be carrying the potentially deadly virus.West Nile virus is mainly a bird disease but can be transmitted to humans via mosquitoes who feed off an infected animal. Symptoms include headache, fever, nausea, fatigue, skin rash or swollen glands.Locals can prevent mosquitoes from breeding by removing any water that is sitting outside of homes or by using mosquito fish to control the bugs in stagnant water sources, like pools, ponds, or fountains. Mosquito repellent that contains DEET, picaridin, oil of lemon eucalyptus, or IR3535 is also recommended. 1123

SAN DIEGO (KGTV) – As more people are being hospitalized with COVID-19 across Southern California, some health care systems worry that lack of hospital staffing could become a big issue.“We’ve got to take care of our health care workers, or we’re not going to have them to take care of the patients,” said Meghan Jaremczuk, a registered nurse and the Director of Progressive and Acute Care at Palomar Medical Center in Escondido.Like many health care workers this year, Jaremczuk hasn’t had a break. She’s been taking care of COVID-19 patients throughout the pandemic.“Other people have been working from home, we're not, we're here, we're in it,” she said. “It’s been hard because this has been going on for a long time and people are tired, but they're still showing up. You're seeing people that can't be with their loved ones, visitors are very, very restricted. They can Facetime with their families and things like that, but it’s not the same.”The County of San Diego reported an additional 15 deaths related to COVID-19 on Wednesday and a 62 percent increase in the number of COVID-19 hospitalized patients in a two week period.The Federal Medical Station set up at Palomar Medical Center in Escondido has 202 beds for non-ICU patients ready to go when needed, according to Palomar Health CEO Diane Hansen.Hansen said the health care system has the ability to expand the dedicated 48 ICU beds to 110 ICU beds if needed, but said making sure enough health care workers are available is one of the bigger issues at this point.“We do have capacity. We're seeing on average about 50 patients per day less than what we normally see this time of year,” said Hansen. “While we have capacity, my biggest concern is our ability to staff beds should the pandemic surge become greater.”“Staffing is a concern because not every nurse can take care of every kind of patient,” said Jaremczuk.Jaremczuk is most worried about the rapid rate of community spread. She said if nurses become sick, hospital operations could be disrupted.While she understands many people are tired of constantly being told to mask up, wash their hands and avoid gatherings, she’s urging everyone to continue to follow the health guidelines to protect those who are giving their all to save lives.“The patients also make an impact on our lives, we make connections and it's meaningful,” she said. “If we get exposed, if we get sick, we can't come to work and take care of patients.” 2459

SAN DIEGO (KGTV) -- As the nation continues to process what happened during the first presidential debate, many are expressing frustration about what didn’t happen.Local and national Latino American leaders are calling out the moderator and the candidates for making no mention of the millions of Latinos in the country.Just moments after the debate ended Tuesday night, organizations like the National Association of Hispanic Journalists shared a series of tweets highlighting that Latinos were not mentioned during the debate.According to the Pew Research Center, more than 32 million Latino voters are eligible to vote in November.Voters like Denisse Roldan Newell wanted to hear more from both candidates about their policies on a range of issues.“It's not just immigration, it's not just the border wall, it's having to do with economics, with smalls business development, with affordable health care, with education,” said Roldan Newell.Roberto Alcantar with the Chicano Federation told ABC 10News it was concerning that the candidates made no mention about COVID-19 and it’s disproportionate affect on the Latino community.In San Diego, Latinos make up 34% of the population but 65% of COVID-19 cases."These are not just Latino issues, these are issues for all of us as American. While, yes, we are Latinos, we are American and our issues are America’s issues," said Alcantar. Locally, Latino leaders like Roldan Newell and Alcantar hope the debate organizers and moderators to make a change before the next debate.The next debate is between the vice presidential candidates on Wednesday, October 7th. 1616

SAN DIEGO (KGTV) — At least six companies are working on COVID-19 vaccine candidates in San Diego, all within a 1.5-mile radius of where the I-5 and I-805 split.Locally, the farthest along appears to be Inovio Pharmaceuticals, which plans to launch a Phase 2 trial next month, potentially with a simultaneous Phase 3 trial. A Phase 3 trial is the final step in vaccine testing, with thousands of participants.The company is developing the vaccine using a DNA technique that isn’t used in any other vaccines on the market, although some are in the final stages of testing, said Dr. Kate Broderick, who leads Inovio’s vaccine program.To ensure the DNA enters a person’s cells, the company uses a proprietary device about the size of a toothbrush to deliver doses into the skin rather than a needle and syringe. The company announced Tuesday it secured a million grant from the Department of Defense to speed up production of the devices.Just down the street, TriLink Biotechnologies is working with researchers in London on a vaccine candidate that replicates itself in the body. It just started a Phase 1 trial this month.Nearby, Sorrento Therapeutics is working on both a COVID-19 vaccine and a treatment, but it hasn’t advanced yet to human trials. 10News previously featured the company’s efforts, which are based on techniques developed to fight cancer.On the other side of the 805, Arcturus Therapeutics is working with Duke University on a vaccine based on RNA, which acts as a messenger for DNA. There are no vaccines approved for humans that use this RNA approach. Trials are expected to begin in August, according to a tracker by the Milken Institute.UC San Diego is developing a vaccine using plant virus nanotechnology, leveraging an approach that’s used in vaccines against Hepatitis B and shingles. The university is also taking part in research on a COVID treatment.A spokeswoman for San Francisco-based Vir Biotechnology says the company is using its San Diego satellite office to help crunch data for the work on its vaccine, which is a collaboration with GlaxoSmithKline (GSK).GSK, Janssen, and Pfizer each have vaccine candidates of their own and offices near the 5-805 split, but 10News was not able to immediately confirm if any of those companies were conducting COVID research locally. 2318

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