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LONDON (AP) — Oxford University says trials of a coronavirus vaccine that it is developing with pharmaceutical company AstraZeneca will resume, days after being paused due to a reported side-effect in a patient in the U.K. The university said in large trials such as this “it is expected that some participants will become unwell and every case must be carefully evaluated to ensure careful assessment of safety.” It said globally 18,000 people have received the vaccine so far. Oxford insisted that it is “committed to the safety of our participants.” Pauses in drug trials are commonplace. The Oxford-AstraZeneca vaccine is seen as one of the strongest contenders among the dozens of coronavirus vaccines being tested. 728
LOS ANGELES (AP) — Voters who hate resetting their clocks twice a year took the first step Tuesday to making daylight saving time year-round in California.With nearly 4.5 million ballots counted, Proposition 7 led by more than 62 percent. The measure permits the state Legislature to establish permanent daylight saving time. However, a change in federal law would be required before the initiative can take effect.The time-change issue was fresh on voters' minds when they went to the polls. California and most of the rest of the nation reset clocks last Sunday, falling back on standard time and seeing the day get dark one hour earlier.Democratic Rep. Kansen Chu of San Jose said last month that he sponsored Proposition 7 after his dentist called him to complain about springing forward when clocks are moved up an hour every March. That switch takes away an hour's sleep in the middle of the night as it shifts an hour of sunlight from the morning to the evening.Chu said he investigated the issue further and learned the original reason for implementing daylight saving — to save energy during World War I— no longer seemed to apply to the modern world.Chu said he also came across studies showing an increased risk of car accidents and heart attacks following the spring change when people lose an hour of sleep."It's a public safety measure," Chu said. "And I don't know anybody who really enjoys doing this adjustment of their schedule twice a year."Opponents argued that even if California voters and the Legislature approve year-round daylight saving, the hurdle of getting the federal government to agree is too high given the state's tense relationship with Washington.RELATED CONTENT 1706

LOS ANGELES, Calif. – Kim Kardashian West is speaking out about Kanye West’s mental health and asking the public for “compassion and empathy” as her husband struggles with bipolar disorder.Over the past several days, the self-declared presidential candidate has caused a stir with his comments at a campaign event in South Carolina, as well as on social media.At a rally, West delivered an eccentric campaign introduction speech in which he proposed a million payout to each new mother and decried Harriet Tubman for her work on the Underground Railroad. West's comments about one of the most respected figures in American history drew of opposition from some in the crowd and those who later heard his comments.In a series of rambling social media posts, West suggested he was resisting intervention efforts by his wife, her family and medical professionals. In a series of since-deleted Twitter posts Tuesday, West also wrote that he’s been considering divorcing his wife.The reality star and beauty mogul released a statement on social media Wednesday, saying she’s speaking out about West’s battle with bipolar disorder because of the stigma and misconceptions about mental health. 1196
LOS ANGELES (CNS) - Travelers coming through Los Angeles International and Van Nuys airports and Union Station beginning Wednesday will be required to sign a form acknowledging California's recommended 14-day self-quarantine in response to rising coronavirus rates.The form will be available at travel.lacity.org, Mayor Eric Garcetti said during a coronavirus briefing Monday.Garcetti urged people to not travel over the Thanksgiving holiday, not even to go across town because of how widespread COVID-19 cases have been and that it's too dangerous at this time.Garcetti said he is confident the Los Angeles County Board of Supervisors, which is slated at Tuesday's meeting to discuss coronavirus- related restrictions and closures, will make the right decisions."I know this is not popular with everybody, but if we don't take these actions now, when will we?" Garcetti said. "I know there may be some push and pull ... but I think the policies that (the county Department of Public Health) adopted are clear."Garcetti said when local government has hesitated implementing COVID- 19 restrictions, businesses have had to remain closed for longer because of the spread of the virus. But he also said he knows businesses are struggling."I've spoken with our City Council President (Nury Martinez), I've spoken with our county supervisors, and know that if those orders do come down, where we have to stop outdoor dining or limit the hours of other businesses, we will take the funds that we have in business assistance and surge them into those industries to get us through this period to keep those businesses alive to protect those jobs and to make sure that they can stand up again," Garcetti said.Garcetti said Los Angeles County could be out of hospital beds for coronavirus patients by Christmastime, if the rate of COVID-19 positive cases continues on its current trend.Field hospitals may have to be established if that happens, Garcetti said. However, Garcetti said he doesn't think the U.S. Navy's hospital ship Mercy will need to return. It docked at the Port of Los Angeles for use in non- coronavirus cases over the spring and summer as safeguard against a lack of hospital beds that did not materialize.Garcetti said he had a discussion Monday with President-elect Joe Biden and Vice President-elect Kamala Harris regarding the state of Los Angeles and its fight against COVID-19, telling them the virus will spread further if people don't follow health protocols."It doesn't matter what you've done last week or last month," Garcetti said he told Biden and Harris. "COVID doesn't care what we've done before today."COVID only cares how we are acting right now, and the moment we stop acting to protect lives, the moment we ignore the numbers or hope that somehow they will just go away is the moment lives are lost."COVID-19 testing sites in Los Angeles will be closed Thursday and Friday for Thanksgiving, but will reopen Saturday, Garcetti said. 2968
LOS ANGELES (KGTV) -- The glitz and the glamor are the talk of any award show night - especially on Oscars Sunday. This year, Rita Morena stole the show, making her moment in a dress she's worn on the red carpet before. The dress Rita Moreno wore to accept her best-supporting-actress Oscar in 1962 got another go-round on the #Oscars red carpet https://t.co/gKx0PJdUw7— VANITY FAIR (@VanityFair) March 4, 2018 433
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